- 专利标题： N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO
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申请号： US16755779申请日： 2018-12-07
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公开(公告)号： US20200276219A1公开(公告)日： 2020-09-03
- 发明人: George R. PAINTER , Gregory R. BLUEMLING , Michael G. NATCHUS , David GUTHRIE
- 申请人： EMORY UNIVERSITY
- 国际申请： PCT/US2018/064503 WO 20181207
- 主分类号： A61K31/7068
- IPC分类号： A61K31/7068 ; A61P31/12
摘要：
This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds.
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