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公开(公告)号：US12006504B2
公开(公告)日：2024-06-11
申请号：US17669945
申请日：2022-02-11
发明人： Terence A. Walsh , Daniel Gachotte , Ann Owens Merlo , Paul G. Roessler , James George Metz , Scott Bevan , Jerry M. Kuner
IPC分类号： C12N15/82 , C12P7/6427 , C12N9/10 , C12N9/12
CPC分类号： C12N15/8247 , C12P7/6427 , C12N9/1029 , C12N9/1288
摘要： The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).
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公开(公告)号：US10669554B2
公开(公告)日：2020-06-02
申请号：US15825107
申请日：2017-11-29
发明人： Terence A. Walsh , Daniel Gachotte , Ann Owens Merlo , Paul Gordon Roessler , James Metz , Scott Bevan , Jerry Kuner
摘要： The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).
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公开(公告)号：US20190010510A1
公开(公告)日：2019-01-10
申请号：US16139534
申请日：2018-09-24
发明人： Terence A WALSH , Daniel Gachotte , Ann Owens Merlo , Paul G. Roessler , James Metz , Scott Bevan , Jerry Kuner
摘要： The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).
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公开(公告)号：US20150320003A1
公开(公告)日：2015-11-12
申请号：US14726285
申请日：2015-05-29
发明人： Terence A. Walsh , Daniel Gachotte , Ann Owens Merlo , Dayakar Reddy Pareddy , James Metz , Scott Bevan , Jerry Kuner
CPC分类号： C12N15/8247 , A01H5/10 , A23L11/07 , A23V2002/00 , A61K31/202 , C12N9/1029 , C12N9/1288 , C12P7/6427 , C12P7/6472 , C12Y203/01085
摘要： The invention provides recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms as well as products obtained from such organisms.
摘要翻译： 本发明提供了用多不饱和脂肪酸（PUFA）合成酶遗传修饰的重组宿主生物体，以及允许和/或改善宿主生物体中PUFA生产的一种或多种辅助蛋白质。 本发明还涉及制造和使用这些生物体以及从这些生物获得的产品的方法。
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公开(公告)号：US11168332B2
公开(公告)日：2021-11-09
申请号：US16890740
申请日：2020-06-02
发明人： Terence A. Walsh , Daniel Gachotte , Ann Owens Merlo , Paul Gordon Roessler , James Metz , Scott Bevan , Jerry Kuner
摘要： The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).
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公开(公告)号：US20180310512A9
公开(公告)日：2018-11-01
申请号：US14726285
申请日：2015-05-29
发明人： Terence A. Walsh , Daniel Gachotte , Ann Owens Merlo , Dayakar Reddy Pareddy , James Metz , Scott Bevan , Jerry Kuner
CPC分类号： C12N15/8247 , A01H5/10 , A23L11/07 , A23V2002/00 , A61K31/202 , C12N9/1029 , C12N9/1288 , C12P7/6427 , C12P7/6472 , C12Y203/01085
摘要： The invention provides recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms as well as products obtained from such organisms.
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公开(公告)号：US20180073036A1
公开(公告)日：2018-03-15
申请号：US15825107
申请日：2017-11-29
发明人： Terence A. Walsh , Daniel Gachotte , Ann Owens Merlo , Dayakar Reddy Pareddy , James Metz , Scott Bevan , Jerry Kuner
摘要： The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed),
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公开(公告)号：US11053511B2
公开(公告)日：2021-07-06
申请号：US14726285
申请日：2015-05-29
发明人： Terence A. Walsh , Daniel Gachotte , Ann Owens Merlo , Dayakar Reddy Pareddy , James Metz , Scott Bevan , Jerry Kuner
摘要： The invention provides recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms as well as products obtained from such organisms.
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公开(公告)号：US11237100B2
公开(公告)日：2022-02-01
申请号：US15601157
申请日：2017-05-22
申请人： Dow AgroSciences LLC
摘要： Provided are methods and/or systems having advantages of cost effective, time saving, and informative user-friendly characteristics to accomplish trait introgression. The methods provided comprise determining presence of omega-3 fatty acids (for example docosahexaenoic acid or DHA; docosapentaenoic acid or DPA; Alpha linolenic acid or ALA; and eicosapentaenoic acid or EPA) using Fourier Transformed infra Red (FTIR) spectrum. The use of FTIR enables analysis of the oil contained in the seeds using a multivariate-based Mid-FTIR model. The methods and/or systems provided advantages of non-destructive analysis to provide information to facilitate trait introgression and other breeding applications.
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公开(公告)号：US20170356019A1
公开(公告)日：2017-12-14
申请号：US15601157
申请日：2017-05-22
申请人： Dow AgroSciences LLC
IPC分类号： C12P7/64 , A23L33/105 , G01N21/35 , C12N15/82
CPC分类号： C12P7/6472 , A23L33/105 , A23L33/12 , C12N15/8234 , C12P7/64 , G01N21/35 , G01N2021/3595
摘要： Provided are methods and/or systems having advantages of cost effective, time saving, and informative user-friendly characteristics to accomplish trait introgression. The methods provided comprise determining presence of omega-3 fatty acids (for example docosahexanoic acid or DHA; docosapentaenoic acid or DPA; Alpha linolenic acid or ALA; and eicosapentaenoic acid or EPA) using Fourier Transformed Infra Red (FTIR) spectrum. The use of FTIR enables analysis of the oil contained in the seeds using a multivariate-based Mid-FTIR model. The methods and/or systems provided advantages of non-destructive analysis to provide information to facilitate trait introgression and other breeding applications.
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