公开(公告)号：US09758457B2

公开(公告)日：2017-09-12

申请号：US15243980

申请日：2016-08-23

申请人： Dexlechem GMBH

发明人： Sonja Jost

IPC分类号： C07C29/143 ,  B01J31/24 ,  C07C29/145 ,  C07C67/31 ,  C07F15/00

CPC分类号： C07C29/143 ,  B01J31/2409 ,  B01J31/2457 ,  B01J2231/643 ,  B01J2531/0266 ,  B01J2531/821 ,  B01J2531/90 ,  B01J2531/96 ,  C07B2200/07 ,  C07C29/145 ,  C07C67/31 ,  C07F15/0046 ,  C07C31/205 ,  C07C31/20 ,  C07C69/675

摘要： The invention relates to a method for converting a precatalyst complex to an active catalyst complex, wherein the precatalyst complex and the active catalyst complex comprise a ruthenium atom and an optically active ligand that is insoluble in water, and the active catalyst complex furthermore comprises a monohydride and a water molecule. The method comprises the steps of providing water as an activation solvent system with a pH value equal or below 2, and solving said precatalyst complex, an acid, and hydrogen therein. The invention further relates to a method for manufacturing a catalyst composition, a method for hydrogenating a substrate molecule and a reaction mixture.

公开(公告)号：US09433937B2

公开(公告)日：2016-09-06

申请号：US14772393

申请日：2014-03-05

申请人： Dexlechem GMBH

发明人： Sonja Jost

IPC分类号： C07C29/145 ,  B01J31/24 ,  C07C67/31 ,  C07F15/00

CPC分类号： C07C29/143 ,  B01J31/2409 ,  B01J31/2457 ,  B01J2231/643 ,  B01J2531/0266 ,  B01J2531/821 ,  B01J2531/90 ,  B01J2531/96 ,  C07B2200/07 ,  C07C29/145 ,  C07C67/31 ,  C07F15/0046 ,  C07C31/205 ,  C07C31/20 ,  C07C69/675

摘要： The invention relates to a method for converting a precatalyst complex to an active catalyst complex, wherein the precatalyst complex and the active catalyst complex comprise a ruthenium atom and an optically active ligand that is insoluble in water, and the active catalyst complex furthermore comprises a monohydride and a water molecule. The method comprises the steps of providing water as an activation solvent system with a pH value equal or below 2, and solving said precatalyst complex, an acid, and hydrogen therein. The invention further relates to a method for manufacturing a catalyst composition, a method for hydrogenating a substrate molecule and a reaction mixture.

摘要翻译： 本发明涉及一种将预催化剂复合物转化为活性催化剂络合物的方法，其中预催化剂络合物和活性催化剂络合物包含不溶于水的钌原子和光学活性配体，并且活性催化剂络合物还包含一价酐 和水分子。 该方法包括提供水作为pH值等于或小于2的活化溶剂体系，并且在其中求解所述预催化剂络合物，酸和氢。 本发明还涉及一种制备催化剂组合物的方法，一种用于氢化底物分子和反应混合物的方法。