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公开(公告)号：US4893631A
公开(公告)日：1990-01-16
申请号：US160146
申请日：1988-02-25
IPC分类号： A61B5/0245 , A61B5/021 , A61B5/022
CPC分类号： A61B5/021 , A61B5/02116
摘要： A method for monitoring a transducer array of individual pressure or force sensitive elements and for selecting the element within the array which most tracks the actual pulse waveform in an underlying artery, thus providing the most accurate measurement of the patient's blood pressure. The outputs of all of the transducer elements are employed in locating the particular element which is centrally located over the artery. A limited number of elements exhibiting local minima of diastolic pressure is first chosen. Then, pulse amplitude outputs from the limited number of transducer elements are employed in selecting that element within the limited-number group which is to be used for obtaining blood pressure measurements. The method provided by the present invention selects from the limited-number group of elements that element about which is centered the greatest spatially weighted average of a predetermined number of pulse amplitude values.
摘要翻译： 用于监测各个压力或力敏感元件的换能器阵列并用于选择阵列内的元件的方法，其大部分跟踪潜在动脉中的实际脉搏波形，从而提供对患者血压的最准确的测量。 所有换能器元件的输出用于定位位于动脉上方的特定元件。 首先选择显示局部舒张压最小值的有限数量的元件。 然后，采用有限数量的换能器元件的脉冲振幅输出来选择用于获得血压测量的有限数量组内的元件。 本发明提供的方法从有限数量的元素组中选择元素，该元素以以预定数量的脉冲振幅值的最大空间加权平均为中心的元素。
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2.发明授权
公开(公告)号：US4836213A
公开(公告)日：1989-06-06
申请号：US160134
申请日：1988-02-25
IPC分类号： A61B5/0245 , A61B5/021 , A61B5/022
CPC分类号： A61B5/021
摘要： A method for computing optimal hold down pressure for a transducer comprising an array of pressure sensing elements for generation of electrical waveforms indicative of blood pressure in an artery. Using the selected pressure sensing element that is determined to be positioned substantially over the center of the underlying artery, a set of data corresponding to the diastolic pressure and the pulse amplitude pressure is collected and stored. The diastolic pressures and pulse amplitude pressures are taken as a function of hold down pressure over a range of hold down pressures between the pressure at which the artery is unflattened and the pressure at which the artery is occluded. First and second polynomials are fitted to the diastolic pressure data set and the pulse amplitude data set, respectively. The hold-down pressure at the point of minimum slope of the first polynomial fitted to the diastolic versus hold-down pressures values provides one estimate of the correct hold-down pressure. Another estimate of the correct hold-down pressure using the pulse amplitude measurements is provided by locating the point where the slope of the second polynomial is zero. In another embodiment of the method of the present invention, the two above described estimates are combined into a single estimate.
摘要翻译： 一种用于计算换能器的最佳压紧压力的方法，包括用于产生指示动脉血压的电波形的压力感测元件阵列。 使用被确定为基本上位于下面的动脉中心的所选择的压力感测元件，收集并存储对应于舒张压和脉搏幅度压力的一组数据。 舒张压和脉搏幅度压力作为在动脉未平坦的压力与动脉闭塞的压力之间的压紧压力范围内的压紧压力的函数。 第一和第二多项式分别拟合到舒张压数据集和脉冲幅度数据集。 拟合到舒张压降压力值的第一个多项式的最小斜率点处的压紧压力提供了正确压紧压力的一个估计值。 通过定位第二多项式的斜率为零的点来提供使用脉冲幅度测量值的正确压紧压力的另一估计。 在本发明方法的另一个实施例中，将上述两个估计值组合成单个估计值。
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公开(公告)号：US5555880A
公开(公告)日：1996-09-17
申请号：US190322
申请日：1994-01-31
IPC分类号： A61M16/00
CPC分类号： A61M16/0096 , A61M16/0069 , A61M2016/0039
摘要： A high frequency oscillatory ventilator for infants and adults using feedback control to maintain either the desired tidal volume or pressure delivered to the subject. The inspiratory to expiratory time ratio of the ventilator is variable. The ventilator corrects the measured pressure for arbitrarily-sized endotracheal tubes and calculates the actual pressure or tidal volume delivered to the subject. The ventilator also separates the source of the tidal volume oscillations from the patient circuit with a flexible membrane or diaphragm, allowing transmission of oscillating tidal volumes while blocking mean airway pressures. The patient circuit is flexible, but fabricated from low-compliance material to minimize the loss of tidal volume. The ventilator uses feedback control of the exhaust flow to maintain mean airway pressure in the presence of an independently controlled bias flow. Further, a respiratory impedance measurement system is built into or connected to the patient circuit which monitors changes in lung mechanics while the patient is connected to the high frequency ventilator without changing mean airway pressure or removing the patient from the ventilator.
摘要翻译： 用于婴儿和成年人的高频振荡呼吸机，使用反馈控制来保持传递给受试者的所需潮气量或压力。 呼吸机吸气与呼气时间的比值是可变的。 呼吸机校正任意尺寸的气管插管的测量压力，并计算输送给受试者的实际压力或潮气量。 呼吸机还通过柔性膜或隔膜将潮气量振荡源与患者回路分开，允许振荡潮气量的传播，同时阻止平均气道压力。 患者电路是柔性的，但由低顺应性材料制成，以尽量减少潮气量的损失。 呼吸机使用排气流的反馈控制来在存在独立控制的偏流的情况下维持平均气道压力。 此外，呼吸阻抗测量系统内置或连接到患者电路，其在病人连接到高频呼吸机而不改变平均气道压力或从呼吸机移除患者时监测肺力学变化。
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4.发明授权
公开(公告)号：US4924871A
公开(公告)日：1990-05-15
申请号：US160573
申请日：1988-02-26
申请人： Kevin S. Honeyager
发明人： Kevin S. Honeyager
CPC分类号： A61B5/021 , A61B2562/0247 , A61B2562/046 , A61B5/7207
摘要： A method for detecting motion artifacts in data obtained from a blood pressure monitoring transducer is provided which prevents erroneous data related to such artifacts from interfering with the accuracy of the blood pressure measurement by way of continuously monitoring the pressure control source which maintains the transducer hold down pressure, and temporarily delaying data acquisition in the event the hold down pressure changes in excess of a predetermined limit.
摘要翻译： 提供了一种用于检测从血压监测换能器获得的数据中的运动伪影的方法，其通过连续监视维持换能器压力的压力控制源来防止与这些伪影有关的错误数据干扰血压测量的精度 在压力压力变化超过预定极限的情况下暂时延迟数据采集。
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公开(公告)号：US06480111B2
公开(公告)日：2002-11-12
申请号：US09758840
申请日：2001-01-10
IPC分类号： G08B2300
摘要： A method and system for physiological monitoring using a microprocessor-enhanced magnetic field sensor to measure the mechanical effects of body motion is described. The measurements may be used for a variety of applications, such as detection of respiration, cardiac rhythms, and blood pressure. The source or detector may be made sufficiently small so as to be implantable. The system is sufficiently sensitive to provide output data for very small movements.
摘要翻译： 描述了使用微处理器增强型磁场传感器来测量身体运动的机械效应的用于生理监测的方法和系统。 测量可用于各种应用，例如呼吸检测，心律和血压。 源或检测器可以制成足够小以便可植入。 该系统足够敏感以提供非常小的运动的输出数据。
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6.发明授权
公开(公告)号：US5005581A
公开(公告)日：1991-04-09
申请号：US160790
申请日：1988-02-25
申请人： Kevin S. Honeyager
发明人： Kevin S. Honeyager
IPC分类号： A61B5/0245 , A61B5/0225 , G06F17/00
CPC分类号： A61B5/0225
摘要： A method and apparatus is provided for detecting motion artifacts in data obtained from a blood pressure monitoring transducer and for preventing erroneous data related to such artifacts from interfering with the accuracy of the blood pressure measurement. Operation includes the steps of monitoring the amplitude of a pulse waveform from a first pulse to a next successive pulse and determining if the output signal changes by more than a predetermined percentage, thus indicating a motion condition.
摘要翻译： 提供一种用于检测从血压监测换能器获得的数据中的运动伪影并防止与这种假象相关的错误数据干扰血压测量精度的方法和装置。 操作包括以下步骤：监视从第一脉冲到下一个连续脉冲的脉搏波形的幅度，并确定输出信号是否改变超过预定百分比，从而指示运动状态。
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公开(公告)号：US07137955B2
公开(公告)日：2006-11-21
申请号：US10418207
申请日：2003-04-18
IPC分类号： A61B5/04
CPC分类号： A61B5/02125 , A61B5/02 , A61B5/024 , A61B5/0285 , A61B5/0816 , A61B5/6817 , A61B5/7221 , A61B7/023 , A61B7/04
摘要： Methods and systems for determining cardiovascular parameters of a patient. In an exemplary embodiment, the method includes placing a phonocardiogram sensor on a patient's body at a first distal location to the heart, and a blood-pressure waveform sensor at a second distal location to the heart. Then, a first set and a second set of waveforms is obtained from the phonocardiogram sensor and the blood-pressure waveform sensor, respectively. A signal processing or conditioning operation may optionally be performed using the first and second sets of waveforms. Then, a time delay between a dicrotic notch signal and an S2 signal is determined. A blood pressure pulse transit time value is calculated by adding S2D, representing a time delay between a patient's heart valve closure time and an arrival time of the S2 signal at the first distal location, to the time delay between a dicrotic notch signal and an S2 signal. Cardiovascular parameters are then determined using the determined blood pressure pulse transit time and at least one physical parameter representative of a arterial distance between a location of the aortic valve and a location of the blood-pressure waveform sensor.
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公开(公告)号：US06656135B2
公开(公告)日：2003-12-02
申请号：US09789832
申请日：2001-02-20
申请人： Susan W. Zogbi , Larry D. Canady , Jerome A. Helffrich , Stephen A. Cerwin , Kevin S. Honeyager , Armando de los Santos , Christopher B. Catterson
发明人： Susan W. Zogbi , Larry D. Canady , Jerome A. Helffrich , Stephen A. Cerwin , Kevin S. Honeyager , Armando de los Santos , Christopher B. Catterson
IPC分类号： A61B5103
CPC分类号： A61B5/4504 , A61B5/0031 , A61B5/103 , A61B5/1121 , A61B5/1126 , A61B5/6878 , A61B5/6883 , A61B17/88 , A61B90/06
摘要： A system that remotely measures displacement between two objects. A passive sensor is affixed between the objects. The internal sensor uses magnetic coupling between two sensor elements to measure their relative displacement. The sensors are either a) a permeable rod and a complimentary coil in parallel with a tuning capacitor; or b) two permeable rods, each having its own surrounding coil and a tuning capacitor. One of the sensor elements is affixed to each object which is to be monitored. When an interrogating device is placed near the sensors, a resonance can be measured whose frequency characteristics change in a reproducible manner with the relative displacement of the sensors. The resulting resonance characteristics can be calibrated in such a way as to enable the displacement of the objects to be determined.
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公开(公告)号：US6111501A
公开(公告)日：2000-08-29
申请号：US339593
申请日：1999-06-24
IPC分类号： A61B5/0205 , A61B5/022 , A61B5/024 , G01W1/17 , G08B19/00
CPC分类号： G01W1/17 , A61B5/02055 , A61B2560/0242 , A61B5/022 , A61B5/02438
摘要： A hand-held monitor (10) for monitoring environmental or physiological conditions affecting the user. The monitor (10) has a main housing (10a) and a sensor module (10b). The sensor module (10b) has a plurality of sensors (33-36) extending from it. The sensor module (10b) is generally cylindrical in shape and rests in a curved cradle (14c) of the main housing (10a). This permits the sensor module (10b) to rotate between a position in which the sensors are deployed and extend outwardly from the main housing (10a), and a position in which the sensors rest in the main housing (10a). The main housing (10a) contains processor-based electronics circuitry (50) for processing the data acquired by the sensors. The sensor module (10b) contains sensor electronics circuitry (60), including all circuitry unique to the sensors, and is easily detachable from the main housing (10a). This permits sensor modules having the same or different sensors to be easily interchanged.
摘要翻译： 一种用于监测影响用户的环境或生理状况的手持式监视器（10）。 监视器（10）具有主壳体（10a）和传感器模块（10b）。 传感器模块（10b）具有从其延伸的多个传感器（33-36）。 传感器模块（10b）通常为圆柱形，并且位于主壳体（10a）的弯曲的支架（14c）中。 这允许传感器模块（10b）在传感器展开的位置和从主壳体（10a）向外延伸的位置之间旋转，以及传感器处于主壳体（10a）中的位置。 主壳体（10a）包含用于处理由传感器获取的数据的基于处理器的电子电路（50）。 传感器模块（10b）包含传感器电子电路（60），其包括传感器独有的所有电路，并且易于从主壳体（10a）拆卸。 这允许具有相同或不同传感器的传感器模块易于互换。
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