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    Polymeric microfibrous filter sheet, preparation and use
    1.
    发明授权
    Polymeric microfibrous filter sheet, preparation and use 失效
    聚合微纤维过滤片，制备和使用

    公开(公告)号：US4617124A

    公开(公告)日：1986-10-14

    申请号：US397762

    申请日：1982-07-13

    申请人： David B. Pall ,  Peter J. Degen ,  Thomas C. Gsell

    发明人： David B. Pall ,  Peter J. Degen ,  Thomas C. Gsell

    IPC分类号： A61L2/02 ,  B01D39/08 ,  B01D39/16 ,  C02F1/28 ,  D06M15/00 ,  D06M101/00 ,  D06M101/16 ,  B01D13/00

    CPC分类号： C02F1/285 ,  A61L2/022 ,  B01D39/163 ,  B01D2239/04 ,  B01D2239/0421 ,  B01D2239/0471 ,  B01D2239/08 ,  B01D2239/10 ,  B01D2239/1216 ,  B01D2239/1233 ,  B01D2239/1291

    摘要： Microfibrous, polymeric filter sheets and filter elements prepared therefrom comprised of a normally hydrophobic, microfibrous, polymeric web, wherein the surfaces of the microfibers making up the web are coated with a cured, precipitated, cationic, thermosetting binder resin or polymer. The filter sheet is further characterized by being hydrophilic and having a positive zeta potential.The process for preparing such filter sheets comprises four steps:(1) applying a first solution or dispersion of a precipitating agent to a hydrophobic web to at least partially wet the web;(2) applying a second solution of the binder resin or polymer to the wetted web of step (1);(3) working the wetted web of step (2) to mix the first and second solutions, thereby facilitating the precipitation of the binder resin or polymer and the distribution of the precipitated binder resin or polymer as a coating on the surface of the microfibers making up the worked web; and(4) drying and curing the coated web of step (3) to form the desired filter sheets.The filter sheets have enhanced mechanical strength, are hydrophilic, have positive zeta potentials over the pH range of from about 3 to about 10 and typically have absolute pore ratings of from about 0.5 to about 80 micrometers.

    摘要翻译： 微纤维，聚合物过滤片和由其制备的过滤元件由通常疏水的微纤维聚合物纤维网组成，其中构成网的微纤维的表面涂覆有固化的，沉淀的阳离子型热固性粘合剂树脂或聚合物。 该滤纸的特征还在于亲水性并具有正的ζ电位。 制备这种过滤片的方法包括四个步骤：（1）将沉淀剂的第一溶液或分散体施加到疏水性网状物上以至少部分地润湿网; （2）将粘合剂树脂或聚合物的第二溶液施加到步骤（1）的润湿网上; （3）加工步骤（2）的湿纸幅以混合第一和第二溶液，从而促进粘合剂树脂或聚合物的沉淀和沉淀的粘合剂树脂或聚合物作为涂层在微细纤维表面上的分布 上网; 和（4）干燥和固化步骤（3）的涂布网以形成所需的过滤片。 过滤片具有增强的机械强度，亲水性，在约3至约10的pH范围内具有正ζ电位，并且通常具有约0.5至约80微米的绝对孔径。

    Fibrous structure and method of manufacture
    2.
    发明授权
    Fibrous structure and method of manufacture 失效
    纤维结构和制造方法

    公开(公告)号：US4702947A

    公开(公告)日：1987-10-27

    申请号：US846803

    申请日：1986-04-01

    申请人： David B. Pall ,  Peter J. Degen ,  Thomas C. Gsell ,  Eleni C. Yanakis

    发明人： David B. Pall ,  Peter J. Degen ,  Thomas C. Gsell ,  Eleni C. Yanakis

    IPC分类号： D04H1/56 ,  D04H1/64 ,  B32B27/00

    CPC分类号： D04H1/56 ,  D04H1/587 ,  D04H1/64 ,  Y10S261/72 ,  Y10S428/903 ,  Y10T428/1372 ,  Y10T442/614

    摘要： Polymeric microfibrous structures comprised of normally hydrophobic microfibers coated with a cured, precipitated, cationic, thermosetting binder resin or polymer and characterized by being hydrophilic and having a positive zeta potential with enhanced capability for the removal of negatively-charged particulate material in a fluid medium are prepared by a process comprising the steps:(1) combining in a controlled manner a first solution of a water-soluble, non-colloidal, cationic, thermosetting binder resin or polymer and a second solution or dispersion of a precipitating agent to form a stable emulsion or suspension;(2) impregnating the microfibrous structure of normally hydrophobic microfibers with the stable emulsion or suspension to form a fibrous structure wetted with the stable emulsion or suspension; and(3) drying the wetted microfibrous structure and curing the binder resin or polymer.

    摘要翻译： 聚合物微纤维结构包括用固化，沉淀，阳离子，热固性粘合剂树脂或聚合物涂覆的通常疏水的微纤维，其特征在于亲水性并具有增强的在流体介质中去除带负电荷的颗粒材料的能力的正ζ电位， 通过包括以下步骤的方法制备：（1）以受控的方式组合水溶性非胶体阳离子热固性粘合剂树脂或聚合物的第一溶液和沉淀剂的第二溶液或分散体以形成稳定的 乳液或悬浮液; （2）用稳定的乳液或悬浮液浸渍通常疏水的微纤维的微纤维结构，以形成用稳定的乳液或悬浮液润湿的纤维结构; 和（3）干燥湿润的微纤维结构并固化粘合剂树脂或聚合物。

    Method of reducing the adhesion of bubbles in medical equipment
    3.
    发明授权
    Method of reducing the adhesion of bubbles in medical equipment 失效
    减少医疗设备中气泡粘附的方法

    公开(公告)号：US4861617A

    公开(公告)日：1989-08-29

    申请号：US075658

    申请日：1987-07-20

    申请人： David B. Pall ,  Peter J. Degen ,  Vlado I. Matkovich ,  Thomas C. Gsell

    发明人： David B. Pall ,  Peter J. Degen ,  Vlado I. Matkovich ,  Thomas C. Gsell

    IPC分类号： A61L29/08 ,  A61M5/36

    CPC分类号： A61M5/36 ,  A61L29/085

    摘要： A method of reducing the adhesion of bubbles to the surfaces of a medical administration set with which a parenteral liquid comes in contact prior to its introduction into a patient by treating the surfaces of the medical administration set with which the liquid comes in contact to increase the critical surface tension thereof prior to contacting the surfaces of the medical administration set with the liquid, preferably by radiation grafting with a solution of a monofunctional monomer compound.

    摘要翻译： 通过对与液体接触的医疗管理装置的表面进行处理而将气泡粘附到肠胃外液体在其被引入患者体内之前与其接触的医疗管理装置的表面的方法， 在将药物给药装置的表面与液体接触之前，优选通过用单官能单体化合物的溶液进行辐射接枝之前，其临界表面张力。

    Charge-modified microfiber filter sheets
    4.
    发明授权
    Charge-modified microfiber filter sheets 失效
    充电改性微纤维过滤片

    公开(公告)号：US4734208A

    公开(公告)日：1988-03-29

    申请号：US716970

    申请日：1985-03-28

    申请人： David B. Pall ,  Peter J. Degen ,  Irving B. Joffee ,  Warren M. Foss ,  Thomas C. Gsell

    发明人： David B. Pall ,  Peter J. Degen ,  Irving B. Joffee ,  Warren M. Foss ,  Thomas C. Gsell

    IPC分类号： B01D39/20 ,  B01D13/00

    CPC分类号： B01D39/2024 ,  B01D2239/0471

    摘要： Filter media comprised of charge modified, resin coated inorganic microfibers are prepared by mixing inorganic microfibers with an aqueous solution of a water soluble, noncolloidal cationic thermosetting binder resin to form a dispersion, following which a precipitating agent is added to precipitate the binder resin and coat the microfibers. The coated microfibers may be used in the dispersed or suspended form as a filter aid. Preferably they are formed into a filter sheet which is then dried and cured to form a filter sheet of narrowly distributed pore size, pore sizes as small as one-half micron, and having a positive zeta potential in alkaline media. Glass is the preferred microfiber and polyamine-epichlorohydrins the preferred resins. By providing the normally negative zeta potential microfibers with a positive zeta potential the binder resins used to coat the microfibers substantially enhance particulate removal capabilities of the microfiber filter sheet.

    摘要翻译： 通过将无机微纤维与水溶性非胶体阳离子热固性粘合剂树脂的水溶液混合以形成分散体来制备由电荷改性的树脂涂覆的无机微纤维组成的过滤介质，形成分散体，随后加入沉淀剂以沉淀粘合剂树脂和涂层 微纤维。 涂覆的微纤维可以以分散或悬浮形式用作助滤剂。 优选地，它们被形成为过滤片，然后将其干燥和固化以形成窄分布孔径，孔径小至半微米，并且在碱性介质中具有正ζ电位的滤片。 玻璃是优选的超细纤维，多胺 - 表氯醇是优选的树脂。 通过提供具有正ζ电位的正负ζ电位微纤维，用于涂覆微纤维的粘合剂树脂基本上增强了微纤维过滤片的微粒去除能力。

    Charge-modified microfiber filter sheets
    5.
    发明授权
    Charge-modified microfiber filter sheets 失效

    公开(公告)号：US4523995A

    公开(公告)日：1985-06-18

    申请号：US312723

    申请日：1981-10-19

    申请人： David B. Pall ,  Peter J. Degen ,  Irving B. Joffee ,  Warren M. Foss ,  Thomas C. Gsell

    发明人： David B. Pall ,  Peter J. Degen ,  Irving B. Joffee ,  Warren M. Foss ,  Thomas C. Gsell

    IPC分类号： B01D39/14 ,  B01D39/20 ,  B01J20/28 ,  B01J20/30 ,  B01D13/00

    CPC分类号： B01D39/2024 ,  B01D2239/0471

    摘要： Filter media comprised of charge modified, resin coated inorganic microfibers are prepared by mixing inorganic microfibers with an aqueous solution of a water soluble, noncolloidal cationic thermosetting binder resin to form a dispersion, following which a precipitating agent is added to precipitate the binder resin and coat the microfibers. The coated microfibers may be used in the dispersed or suspended form as a filter aid. Preferably they are formed into a filter sheet which is then dried and cured to form a filter sheet of narrowly distributed pore size, pore sizes as small as one-half micron, and having a positive zeta potential in alkaline media. Glass is the preferred microfiber and polyamine-epichlorohydrins the preferred resins. By providing the normally negative zeta potential microfibers with a positive zeta potential the binder resins used to coat the microfibers substantially enhance particulate removal capabilities of the microfiber filter sheet.

    Device for depletion of the leucocyte content of blood and blood components
    10.
    发明授权
    Device for depletion of the leucocyte content of blood and blood components 失效
    用于消除血液和血液成分的白细胞含量的装置

    公开(公告)号：US5501795A

    公开(公告)日：1996-03-26

    申请号：US277426

    申请日：1994-07-18

    申请人： David B. Pall ,  Thomas C. Gsell

    发明人： David B. Pall ,  Thomas C. Gsell

    IPC分类号： A61M1/36 ,  B01D39/14 ,  B01D39/16 ,  B01D27/02 ,  B01D39/02

    CPC分类号： B01D39/14 ,  A61M1/3633 ,  A61M1/3679 ,  B01D39/1623 ,  A61M2202/0413 ,  A61M2202/0439

    摘要： A high efficiency leucocyte-depletion filter for use with packed red cell concentrate derived from freshly drawn blood comprises a fibrous filter medium with a pore size of from about 0.5 to less than 3.6 .mu.m and a CWST of from 53 to about 80. The filter is preferably used in conjunction with a gel prefilter and, optionally, a microaggregate filter so as to minimize clogging. In a preferred embodiment, the voids volume is about 60% to about 85%.

    摘要翻译： 用于来自新鲜抽取的血液的包装红细胞浓缩物的高效白细胞消耗过滤器包括孔径为约0.5至小于3.6μm的纤维过滤介质和约53至约80的CWST。过滤器 优选与凝胶预过滤器和任选的微团聚过滤器结合使用以最小化堵塞。 在优选的实施方案中，空隙体积为约60％至约85％。