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公开(公告)号:US12091395B2
公开(公告)日:2024-09-17
申请号:US18501481
申请日:2023-11-03
Applicant: Daiichi Sankyo Company, Limited
Inventor: Keiji Saito , Katsuyoshi Nakajima , Toru Taniguchi , Osamu Iwamoto , Satoshi Shibuya , Yasuyuki Ogawa , Kazumasa Aoki , Nobuya Kurikawa , Shinji Tanaka , Momoko Ogitani , Eriko Kioi , Kaori Ito , Natsumi Nishihama , Tsuyoshi Mikkaichi , Wataru Saitoh
IPC: C07D307/94 , A61K31/343 , A61K31/4155 , A61K31/4245 , C07D405/04 , C07D405/10 , C07D407/12 , C07D413/04 , C07D413/10 , C07D413/14
CPC classification number: C07D307/94 , A61K31/343 , A61K31/4155 , A61K31/4245 , C07D405/04 , C07D405/10 , C07D407/12 , C07D413/04 , C07D413/10 , C07D413/14
Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof.
The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof.
wherein the symbols in the formula are defined below: R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.-
公开(公告)号:US11834427B2
公开(公告)日:2023-12-05
申请号:US18046270
申请日:2022-10-13
Applicant: Daiichi Sankyo Company, Limited
Inventor: Keiji Saito , Katsuyoshi Nakajima , Toru Taniguchi , Osamu Iwamoto , Satoshi Shibuya , Yasuyuki Ogawa , Kazumasa Aoki , Nobuya Kurikawa , Shinji Tanaka , Momoko Ogitani , Eriko Kioi , Kaori Ito , Natsumi Nishihama , Tsuyoshi Mikkaichi , Wataru Saitoh
IPC: C07D307/94 , C07D405/04 , C07D405/10 , C07D407/12 , C07D413/04 , C07D413/14 , A61K31/343 , A61K31/4155 , A61K31/4245 , C07D413/10
CPC classification number: C07D307/94 , A61K31/343 , A61K31/4155 , A61K31/4245 , C07D405/04 , C07D405/10 , C07D407/12 , C07D413/04 , C07D413/10 , C07D413/14
Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof.
The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof.
wherein the symbols in the formula are defined below:
R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group;
A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.-
公开(公告)号:US20190092741A1
公开(公告)日:2019-03-28
申请号:US16088696
申请日:2017-03-29
Applicant: Daiichi Sankyo Company, Limited
Inventor: Keiji Saito , Katsuyoshi Nakajima , Toru Taniguchi , Osamu Iwamoto , Satoshi Shibuya , Yasuyuki Ogawa , Kazumasa Aoki , Nobuya Kurikawa , Shinji Tanaka , Momoko Ogitani , Eriko Kioi , Kaori Ito , Natsumi Nishihama , Tsuyoshi Mikkaichi , Wataru Saitoh
IPC: C07D307/94 , C07D413/14 , C07D413/10 , C07D405/10 , C07D407/12
Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof.The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.
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公开(公告)号:US10654821B2
公开(公告)日:2020-05-19
申请号:US16561459
申请日:2019-09-05
Applicant: Daiichi Sankyo Company, Limited
Inventor: Keiji Saito , Katsuyoshi Nakajima , Toru Taniguchi , Osamu Iwamoto , Satoshi Shibuya , Yasuyuki Ogawa , Kazumasa Aoki , Nobuya Kurikawa , Shinji Tanaka , Momoko Ogitani , Eriko Kioi , Kaori Ito , Natsumi Nishihama , Tsuyoshi Mikkaichi , Wataru Saitoh
IPC: C07D307/94 , C07D405/10 , C07D413/14 , C07D413/10 , C07D407/12
Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof.The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.
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公开(公告)号:US20200002302A1
公开(公告)日:2020-01-02
申请号:US16561459
申请日:2019-09-05
Applicant: Daiichi Sankyo Company, Limited
Inventor: Keiji Saito , Katsuyoshi Nakajima , Toru Taniguchi , Osamu Iwamoto , Satoshi Shibuya , Yasuyuki Ogawa , Kazumasa Aoki , Nobuya Kurikawa , Shinji Tanaka , Momoko Ogitani , Eriko Kioi , Kaori Ito , Natsumi Nishihama , Tsuyoshi Mikkaichi , Wataru Saitoh
IPC: C07D307/94 , C07D405/10 , C07D407/12 , C07D413/10 , C07D413/14
Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof.The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.
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公开(公告)号:US11981686B2
公开(公告)日:2024-05-14
申请号:US17425520
申请日:2020-01-23
Applicant: DAIICHI SANKYO COMPANY, LIMITED
Inventor: Junya Kawai , Osamu Iwamoto , Yuma Umezaki , Katsuyoshi Nakajima , Hiroyuki Tsuruoka , Keiji Saito , Nobuya Kurikawa , Natsumi Nishihama , Shinji Tanaka , Momoko Ogitani , Tomohiro Honda , Wataru Saitoh , Tsuyoshi Soneda , Nobuyuki Ohkawa
IPC: C07D513/18 , C07D513/04
CPC classification number: C07D513/18 , C07D513/04
Abstract: An object of the present invention is to provide a compound that has a specific chemical structure having an activation effect on SIRT6 and is useful as an active component for preventing and treating inflammatory diseases, and the present invention relates to a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof,
where each symbol in Formula (1) has the same definition as that described in the specification.-
公开(公告)号:US20210292292A1
公开(公告)日:2021-09-23
申请号:US17212373
申请日:2021-03-25
Applicant: Daiichi Sankyo Company, Limited
Inventor: Keiji Saito , Katsuyoshi Nakajima , Toru Taniguchi , Osamu Iwamoto , Satoshi Shibuya , Yasuyuki Ogawa , Kazumasa Aoki , Nobuya Kurikawa , Shinji Tanaka , Momoko Ogitani , Eriko Kioi , Kaori Ito , Natsumi Nishihama , Tsuyoshi Mikkaichi , Wataru Saitoh
IPC: C07D307/94 , C07D405/04 , C07D413/04 , A61K31/4155 , A61K31/4245 , A61K31/343 , C07D405/10 , C07D407/12 , C07D413/10 , C07D413/14
Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof.
The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.-
公开(公告)号:US10975052B2
公开(公告)日:2021-04-13
申请号:US16844621
申请日:2020-04-09
Applicant: Daiichi Sankyo Company, Limited
Inventor: Keiji Saito , Katsuyoshi Nakajima , Toru Taniguchi , Osamu Iwamoto , Satoshi Shibuya , Yasuyuki Ogawa , Kazumasa Aoki , Nobuya Kurikawa , Shinji Tanaka , Momoko Ogitani , Eriko Kioi , Kaori Ito , Natsumi Nishihama , Tsuyoshi Mikkaichi , Wataru Saitoh
IPC: C07D307/94 , C07D405/04 , C07D405/10 , C07D407/12 , C07D413/04 , C07D413/10 , C07D413/14 , A61K31/343 , A61K31/4155 , A61K31/4245
Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof.
The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.-
公开(公告)号:US20230136988A1
公开(公告)日:2023-05-04
申请号:US18046270
申请日:2022-10-13
Applicant: Daiichi Sankyo Company, Limited
Inventor: Keiji Saito , Katsuyoshi Nakajima , Toru Taniguchi , Osamu Iwamoto , Satoshi Shibuya , Yasuyuki Ogawa , Kazumasa Aoki , Nobuya Kurikawa , Shinji Tanaka , Momoko Ogitani , Eriko Kioi , Kaori Ito , Natsumi Nishihama , Tsuyoshi Mikkaichi , Wataru Saitoh
IPC: C07D307/94 , C07D405/04 , C07D413/04 , A61K31/4155 , A61K31/4245 , A61K31/343 , C07D405/10 , C07D407/12 , C07D413/10 , C07D413/14
Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof.
The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.-
公开(公告)号:US11472784B2
公开(公告)日:2022-10-18
申请号:US17212373
申请日:2021-03-25
Applicant: Daiichi Sankyo Company, Limited
Inventor: Keiji Saito , Katsuyoshi Nakajima , Toru Taniguchi , Osamu Iwamoto , Satoshi Shibuya , Yasuyuki Ogawa , Kazumasa Aoki , Nobuya Kurikawa , Shinji Tanaka , Momoko Ogitani , Eriko Kioi , Kaori Ito , Natsumi Nishihama , Tsuyoshi Mikkaichi , Wataru Saitoh
IPC: C07D307/94 , C07D405/04 , C07D405/10 , C07D407/12 , C07D413/04 , C07D413/10 , C07D413/14 , A61K31/343 , A61K31/4155 , A61K31/4245
Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof.
The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.
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