-
公开(公告)号:US11110037B2
公开(公告)日:2021-09-07
申请号:US16554695
申请日:2019-08-29
申请人: DENTSPLY SIRONA Inc.
发明人: Xiaoming Jin , Bassam Usta , Christian Scheufler , Joachim E. Klee , Thomas Tigges , Kira Neuhaus , Jörg Brenneisen , Hui Lu
摘要: The present disclosure relates to methods and compositions to stabilize a nanogel and use of such nanogel as additives in dental compositions.
-
公开(公告)号:US10646409B2
公开(公告)日:2020-05-12
申请号:US15904919
申请日:2018-02-26
申请人: DENTSPLY SIRONA Inc.
发明人: Xiaoming Jin
IPC分类号: A61K6/083 , A61K6/887 , A61K6/17 , A61K6/61 , A61K6/62 , A61K6/77 , A61K6/838 , A61K6/871 , A61K6/891
摘要: Described is a stable, two-component low viscosity composite that is capable to achieve excellent adaptation to walls/substrates due to its intrinsic flow ability and is also capable of rapid viscosity increasing and being manipulated prior to cure by light upon mixing of such a two-paste composite due to one distinguished reaction promoting partial network formation thus to allow a practitioner further manipulate a firm composite. Upon a completed manipulation by the practitioner, such a mixed material should be readily cured into final solid form by using conventional curing light.
-
公开(公告)号:US10849831B2
公开(公告)日:2020-12-01
申请号:US16237983
申请日:2019-01-02
申请人: DENTSPLY SIRONA Inc.
发明人: Caroline Renn , Florian Szillat , Joachim E. Klee , Christian Scheufler , Oliver Elsner , Thomas Tigges , Mattias Worm , Helmut Ritter , Xiaoming Jin
摘要: A dental composition comprising a polymerizable acidic compound of the following formula (I): wherein R1 which may be the same or different when more than one R1 is present, represents a hydrogen atom or a methyl group; R2 which may be the same or different when more than one R2 is present, represents a hydrogen atom, a straight-chain or branched C1-6 alkyl group, a C3-8 cycloalkyl group or a straight-chain or branched C2-6 alkenyl group; R3 which may be the same or different when more than one R3 is present, represents a monovalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; or R2 and R3 form together a divalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; L represents a (m+n+1)-valent organic linker group; X represents a hydrogen atom or a group selected from —COOM, —PO3M, —O—PO3M2 or —SO3M, wherein M independently is a hydrogen atom or a metal atom; m is an integer of 0 to 6; n is an integer of 0 to 6; wherein (m+n) is at least 2; provided that when n is 0, then X cannot be a hydrogen atom.
-
公开(公告)号:US10272017B2
公开(公告)日:2019-04-30
申请号:US15486342
申请日:2017-04-13
申请人: DENTSPLY SIRONA Inc.
发明人: Caroline Renn , Oliver Elsner , Florian Szillat , Joachim Klee , Christoph Weber , Uwe Walz , Christian Scheufler , Andrew Lichkus , Xiaoming Jin
摘要: An aqueous dental glass ionomer composition comprising (A) a reactive particulate glass, (B) a water-soluble polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, (C) a water-soluble, hydrolysis-stable monomer having a single polymerizable double bond and optionally a carboxylic acid group or hydroxyl group; (D) a water-soluble, hydrolysis-stable polymerizable crosslinker having at least two polymerizable carbon-carbon double bonds; and (E) a polymerization initiator system.
-
公开(公告)号:US20170296441A1
公开(公告)日:2017-10-19
申请号:US15486335
申请日:2017-04-13
申请人: DENTSPLY SIRONA Inc.
发明人: Caroline RENN , Oliver Elsner , Maximilian Maier , Florian Szillat , Joachim Klee , Christoph Weber , Uwe Walz , Christian Scheufler , Helmut Ritter , Andrew Lichkus , Xiaoming Jin
IPC分类号: A61K6/083
CPC分类号: A61K6/0835 , C08L33/00 , C08L33/10 , C08L33/08
摘要: The present disclosure relates to an aqueous dental glass ionomer composition comprising a reactive particulate glass, a water-soluble, polymerizable polymer which is reactive with the particulate glass in a cement reaction, a hydrolysis-stable, water-soluble monomer having a single polymerizable double bond and optionally a carboxylic acid group or hydroxyl group; and a polymerization initiator system, wherein the polymerizable polymer is obtainable by a process comprising a step of polymerizing a mixture comprising a first polymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and optionally a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary hydroxyl and/or amino group(s) and a second polymerizable organic moiety, for obtaining an water-soluble polymer; a step of coupling to the water-soluble polymer a compound having a olymerizable moiety and a functional group reactive with an optionally protected carboxylic acid group of repeating units derived from the first polymerizable monomer or an optionally protected hydroxyl and/or amino group of repeating units derived from the second copolymerizable monomer in the water-soluble polymer obtained in step a), wherein the optionally protected carboxylic acid group and the optionally protected hydroxyl and/or amine group are deprotected, so that polymerizable pendant groups are linked to the backbone by ester groups, urethane groups and/or amide groups, and, optionally, a step of deprotecting the protected carboxylic acid group for obtaining a polymerizable polymer.
-
公开(公告)号:US11446215B2
公开(公告)日:2022-09-20
申请号:US16415229
申请日:2019-05-17
申请人: DENTSPLY SIRONA Inc.
发明人: Xiaoming Jin , Yi Liu , Stefano Gulmini , Stefano Cavaliere , Zhaonan Zhang
IPC分类号: A61K6/90 , C08F283/12 , C08G77/20 , C08G77/26
摘要: A light-curable dental impression material comprising
(a) a polymerizable polysiloxane resin composition comprising compounds of formula (I) E−(L1−Z)n−L2−E (I) (b) a particulate filler; and (c) a photoinitiator.-
公开(公告)号:US11319392B2
公开(公告)日:2022-05-03
申请号:US16555217
申请日:2019-08-29
申请人: DENTSPLY SIRONA Inc.
发明人: Xiaoming Jin , Christian Scheufler , Joachim E. Klee , Hui Lu
IPC分类号: C08F220/60 , A61K6/887 , C08F293/00 , C08J3/075 , B82Y30/00
摘要: Described herein are a polymerizable antibacterial nanogel and hydrolytically stable antibacterial nanogel composition and methods of preparing such compositions, use of polymerizable antibacterial nanogels and hydrolytically stable antibacterial nanogels as additives to a dental product, such as a resin monomer, a cement, an adhesive and composite formulations. Methods and compositions for forming hydrolytically stable antibacterial monomers are also described.
-
公开(公告)号:US11110039B2
公开(公告)日:2021-09-07
申请号:US16414986
申请日:2019-05-17
申请人: DENTSPLY SIRONA Inc.
发明人: Xiaoming Jin , Christos Angeletakis , Yi Liu , Joachim E. Klee , Christoph Weber , Xin Huo
IPC分类号: A61K6/90 , C08F283/12 , C08G77/20 , C08G77/26
摘要: A light-curable dental impression material comprising
(a) a polymerizable polysiloxane resin composition comprising compounds of formula (I) E-(L1-Z)n-L2-E (I) (b) a particulate filler; and (c) a photoinitiator.-
公开(公告)号:US20190201297A1
公开(公告)日:2019-07-04
申请号:US16237983
申请日:2019-01-02
申请人: DENTSPLY SIRONA Inc.
发明人: Caroline Renn , Florian Szillat , Joachim E. Klee , Christian Scheufler , Oliver Elsner , Thomas Tigges , Mattias Worm , Helmut Ritter , Xiaoming Jin
CPC分类号: A61K6/0835 , A61K6/0017 , A61K6/0023 , A61K6/0038 , A61K6/0052 , C08L33/26 , C08L33/10 , C08L33/08
摘要: A dental composition comprising a polymerizable acidic compound of the following formula (I): wherein R1 which may be the same or different when more than one R1 is present, represents a hydrogen atom or a methyl group; R2 which may be the same or different when more than one R2 is present, represents a hydrogen atom, a straight-chain or branched C1-6 alkyl group, a C3-8 cycloalkyl group or a straight-chain or branched C2-6 alkenyl group; R3 which may be the same or different when more than one R3 is present, represents a monovalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; or R2 and R3 form together a divalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; L represents a (m+n+1)-valent organic linker group; X represents a hydrogen atom or a group selected from —COOM, —PO3M, —O—PO3M2 or —SO3M, wherein M independently is a hydrogen atom or a metal atom; m is an integer of 0 to 6; n is an integer of 0 to 6; wherein (m+n) is at least 2; provided that when n is 0, then X cannot be a hydrogen atom.
-
公开(公告)号:US09944611B2
公开(公告)日:2018-04-17
申请号:US15352772
申请日:2016-11-16
申请人: DENTSPLY SIRONA INC.
发明人: Xiaoming Jin
IPC分类号: A61K6/083 , C07D251/04 , C07D211/06 , C07F9/6521 , C07F9/6558
CPC分类号: C07D251/04 , A61K6/083 , C07D211/06 , C07F9/6521 , C07F9/65583
摘要: Disclosed herein are methods of making polymerizable resins containing a 1,3,5-hexahydro-1,3,5-triazine moiety and dental compositions comprising such novel hydrolytically-stable, polymerizable resins derived from a 1,3,5-hexahydro-1,3,5-triazine.
-
-
-
-
-
-
-
-
-