-
公开(公告)号:US20190201297A1
公开(公告)日:2019-07-04
申请号:US16237983
申请日:2019-01-02
申请人: DENTSPLY SIRONA Inc.
发明人: Caroline Renn , Florian Szillat , Joachim E. Klee , Christian Scheufler , Oliver Elsner , Thomas Tigges , Mattias Worm , Helmut Ritter , Xiaoming Jin
CPC分类号: A61K6/0835 , A61K6/0017 , A61K6/0023 , A61K6/0038 , A61K6/0052 , C08L33/26 , C08L33/10 , C08L33/08
摘要: A dental composition comprising a polymerizable acidic compound of the following formula (I): wherein R1 which may be the same or different when more than one R1 is present, represents a hydrogen atom or a methyl group; R2 which may be the same or different when more than one R2 is present, represents a hydrogen atom, a straight-chain or branched C1-6 alkyl group, a C3-8 cycloalkyl group or a straight-chain or branched C2-6 alkenyl group; R3 which may be the same or different when more than one R3 is present, represents a monovalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; or R2 and R3 form together a divalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; L represents a (m+n+1)-valent organic linker group; X represents a hydrogen atom or a group selected from —COOM, —PO3M, —O—PO3M2 or —SO3M, wherein M independently is a hydrogen atom or a metal atom; m is an integer of 0 to 6; n is an integer of 0 to 6; wherein (m+n) is at least 2; provided that when n is 0, then X cannot be a hydrogen atom.
-
公开(公告)号:US20170296442A1
公开(公告)日:2017-10-19
申请号:US15486342
申请日:2017-04-13
申请人: DENTSPLY SIRONA Inc.
发明人: Caroline RENN , Oliver Elsner , Florian Szillat , Joachim Klee , Christoph Weber , Uwe Walz , Christian Scheufler , Andrew Lichkus , Xiaoming Jin
CPC分类号: A61K6/0835 , A61K6/0052 , A61K6/0091 , A61K6/083 , C08L33/00 , C08L33/08 , C08L33/10
摘要: An aqueous dental glass ionomer composition comprising (A) a reactive particulate glass, (B) a water-soluble polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, (C) a water-soluble, hydrolysis-stable monomer having a single polymerizable double bond and optionally a carboxylic acid group or hydroxyl group; (D) a water-soluble, hydrolysis-stable polymerizable crosslinker having at least two polymerizable carbon-carbon double bonds; and (E) a polymerization initiator system.
-
公开(公告)号:US10899861B2
公开(公告)日:2021-01-26
申请号:US15754303
申请日:2016-09-09
申请人: DENTSPLY SIRONA inc.
发明人: Joachim Klee , Caroline Renn , Florian Szillat , Oliver Elsner , Christian Scheufler , Ulrich Lampe , Helmut Ritter
IPC分类号: A61F2/00 , C08F220/56 , C08F8/30 , C08F290/12 , C08F220/06 , C07C233/20
摘要: The present invention relates to a polymerizable polyacidic polymer and to a process for preparing the polymerizable polyacidic polymer. Furthermore, the present invention relates to an aqueous dental composition comprising the polymerizable polyacidic polymer, to a use of the polymerizable polyacidic polymer for the preparation of a dental composition and to an acrylic acid derivative copolymer.
-
公开(公告)号:US10449125B2
公开(公告)日:2019-10-22
申请号:US15951319
申请日:2018-04-12
申请人: DENTSPLY SIRONA Inc.
发明人: Joachim E. Klee , Helmut Ritter , Maximilliam Maier , Julia Gansel , Andreas Facher , Oliver Elsner , Sven Pohle
摘要: A process for producing a water-soluble, hydrolysis-stable, polymerizable polymer, comprising a) a step of copolymerizing a mixture comprising (i) a first copolymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and (ii) a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary amino groups and a second polymerizable organic moiety, for obtaining an amino group containing copolymer; b) a step of coupling to the amino group containing copolymer a compound having a polymerizable moiety and a functional group reactive with an amino group of repeating units derived from the second copolymerizable monomer in the amino group containing copolymer obtained in the first step wherein the optionally protected amino group is deprotected, so that polymerizable pendant groups are linked to the backbone by hydrolysis-stable linking groups, and, optionally, a step of deprotecting the protected carboxylic acid group after step (a) or step (b), for obtaining a polymerizable polymer.
-
公开(公告)号:US20180237567A1
公开(公告)日:2018-08-23
申请号:US15754303
申请日:2016-09-09
申请人: DENTSPLY SIRONA inc.
发明人: Joachim KLEE , Caroline RENN , Florian SZILLAT , Oliver Elsner , Christian Scheufler , Ulrich Lampe , Helmut RITTER
IPC分类号: C08F220/56 , C08F290/12 , C08F8/30
CPC分类号: C08F220/56 , C07C233/20 , C08F8/30 , C08F220/06 , C08F290/126 , C08F2800/10 , C08F2800/20 , C08F2810/30 , C08F2810/50 , C08F220/58 , A61K6/0835 , C08L33/10 , A61K6/0023 , C08L33/26
摘要: The present invention relates to a polymerizable polyacidic polymer and to a process for preparing the polymerizable polyacidic polymer. Furthermore, the present invention relates to an aqueous dental composition comprising the polymerizable polyacidic polymer, to a use of the polymerizable polyacidic polymer for the preparation of a dental composition and to an acrylic acid derivative copolymer
-
公开(公告)号:US10849831B2
公开(公告)日:2020-12-01
申请号:US16237983
申请日:2019-01-02
申请人: DENTSPLY SIRONA Inc.
发明人: Caroline Renn , Florian Szillat , Joachim E. Klee , Christian Scheufler , Oliver Elsner , Thomas Tigges , Mattias Worm , Helmut Ritter , Xiaoming Jin
摘要: A dental composition comprising a polymerizable acidic compound of the following formula (I): wherein R1 which may be the same or different when more than one R1 is present, represents a hydrogen atom or a methyl group; R2 which may be the same or different when more than one R2 is present, represents a hydrogen atom, a straight-chain or branched C1-6 alkyl group, a C3-8 cycloalkyl group or a straight-chain or branched C2-6 alkenyl group; R3 which may be the same or different when more than one R3 is present, represents a monovalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; or R2 and R3 form together a divalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; L represents a (m+n+1)-valent organic linker group; X represents a hydrogen atom or a group selected from —COOM, —PO3M, —O—PO3M2 or —SO3M, wherein M independently is a hydrogen atom or a metal atom; m is an integer of 0 to 6; n is an integer of 0 to 6; wherein (m+n) is at least 2; provided that when n is 0, then X cannot be a hydrogen atom.
-
公开(公告)号:US10272017B2
公开(公告)日:2019-04-30
申请号:US15486342
申请日:2017-04-13
申请人: DENTSPLY SIRONA Inc.
发明人: Caroline Renn , Oliver Elsner , Florian Szillat , Joachim Klee , Christoph Weber , Uwe Walz , Christian Scheufler , Andrew Lichkus , Xiaoming Jin
摘要: An aqueous dental glass ionomer composition comprising (A) a reactive particulate glass, (B) a water-soluble polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, (C) a water-soluble, hydrolysis-stable monomer having a single polymerizable double bond and optionally a carboxylic acid group or hydroxyl group; (D) a water-soluble, hydrolysis-stable polymerizable crosslinker having at least two polymerizable carbon-carbon double bonds; and (E) a polymerization initiator system.
-
公开(公告)号:US20170296441A1
公开(公告)日:2017-10-19
申请号:US15486335
申请日:2017-04-13
申请人: DENTSPLY SIRONA Inc.
发明人: Caroline RENN , Oliver Elsner , Maximilian Maier , Florian Szillat , Joachim Klee , Christoph Weber , Uwe Walz , Christian Scheufler , Helmut Ritter , Andrew Lichkus , Xiaoming Jin
IPC分类号: A61K6/083
CPC分类号: A61K6/0835 , C08L33/00 , C08L33/10 , C08L33/08
摘要: The present disclosure relates to an aqueous dental glass ionomer composition comprising a reactive particulate glass, a water-soluble, polymerizable polymer which is reactive with the particulate glass in a cement reaction, a hydrolysis-stable, water-soluble monomer having a single polymerizable double bond and optionally a carboxylic acid group or hydroxyl group; and a polymerization initiator system, wherein the polymerizable polymer is obtainable by a process comprising a step of polymerizing a mixture comprising a first polymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and optionally a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary hydroxyl and/or amino group(s) and a second polymerizable organic moiety, for obtaining an water-soluble polymer; a step of coupling to the water-soluble polymer a compound having a olymerizable moiety and a functional group reactive with an optionally protected carboxylic acid group of repeating units derived from the first polymerizable monomer or an optionally protected hydroxyl and/or amino group of repeating units derived from the second copolymerizable monomer in the water-soluble polymer obtained in step a), wherein the optionally protected carboxylic acid group and the optionally protected hydroxyl and/or amine group are deprotected, so that polymerizable pendant groups are linked to the backbone by ester groups, urethane groups and/or amide groups, and, optionally, a step of deprotecting the protected carboxylic acid group for obtaining a polymerizable polymer.
-
-
-
-
-
-
-