DENTAL COMPOSITION
    1.
    发明申请
    DENTAL COMPOSITION 审中-公开

    公开(公告)号:US20190201297A1

    公开(公告)日:2019-07-04

    申请号:US16237983

    申请日:2019-01-02

    IPC分类号: A61K6/083 A61K6/00

    摘要: A dental composition comprising a polymerizable acidic compound of the following formula (I): wherein R1 which may be the same or different when more than one R1 is present, represents a hydrogen atom or a methyl group; R2 which may be the same or different when more than one R2 is present, represents a hydrogen atom, a straight-chain or branched C1-6 alkyl group, a C3-8 cycloalkyl group or a straight-chain or branched C2-6 alkenyl group; R3 which may be the same or different when more than one R3 is present, represents a monovalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; or R2 and R3 form together a divalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; L represents a (m+n+1)-valent organic linker group; X represents a hydrogen atom or a group selected from —COOM, —PO3M, —O—PO3M2 or —SO3M, wherein M independently is a hydrogen atom or a metal atom; m is an integer of 0 to 6; n is an integer of 0 to 6; wherein (m+n) is at least 2; provided that when n is 0, then X cannot be a hydrogen atom.

    Polymer for a glass ionomer cement

    公开(公告)号:US10449125B2

    公开(公告)日:2019-10-22

    申请号:US15951319

    申请日:2018-04-12

    摘要: A process for producing a water-soluble, hydrolysis-stable, polymerizable polymer, comprising a) a step of copolymerizing a mixture comprising (i) a first copolymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and (ii) a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary amino groups and a second polymerizable organic moiety, for obtaining an amino group containing copolymer; b) a step of coupling to the amino group containing copolymer a compound having a polymerizable moiety and a functional group reactive with an amino group of repeating units derived from the second copolymerizable monomer in the amino group containing copolymer obtained in the first step wherein the optionally protected amino group is deprotected, so that polymerizable pendant groups are linked to the backbone by hydrolysis-stable linking groups, and, optionally, a step of deprotecting the protected carboxylic acid group after step (a) or step (b), for obtaining a polymerizable polymer.

    Dental composition
    6.
    发明授权

    公开(公告)号:US10849831B2

    公开(公告)日:2020-12-01

    申请号:US16237983

    申请日:2019-01-02

    摘要: A dental composition comprising a polymerizable acidic compound of the following formula (I): wherein R1 which may be the same or different when more than one R1 is present, represents a hydrogen atom or a methyl group; R2 which may be the same or different when more than one R2 is present, represents a hydrogen atom, a straight-chain or branched C1-6 alkyl group, a C3-8 cycloalkyl group or a straight-chain or branched C2-6 alkenyl group; R3 which may be the same or different when more than one R3 is present, represents a monovalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; or R2 and R3 form together a divalent organic moiety substituted by a group selected from —COOM, —PO3M, —O—PO3M2 and —SO3M, wherein M independently represents a hydrogen atom or a metal atom; L represents a (m+n+1)-valent organic linker group; X represents a hydrogen atom or a group selected from —COOM, —PO3M, —O—PO3M2 or —SO3M, wherein M independently is a hydrogen atom or a metal atom; m is an integer of 0 to 6; n is an integer of 0 to 6; wherein (m+n) is at least 2; provided that when n is 0, then X cannot be a hydrogen atom.

    AQUEOUS DENTAL GLASS IONOMER COMPOSITION
    8.
    发明申请

    公开(公告)号:US20170296441A1

    公开(公告)日:2017-10-19

    申请号:US15486335

    申请日:2017-04-13

    IPC分类号: A61K6/083

    摘要: The present disclosure relates to an aqueous dental glass ionomer composition comprising a reactive particulate glass, a water-soluble, polymerizable polymer which is reactive with the particulate glass in a cement reaction, a hydrolysis-stable, water-soluble monomer having a single polymerizable double bond and optionally a carboxylic acid group or hydroxyl group; and a polymerization initiator system, wherein the polymerizable polymer is obtainable by a process comprising a step of polymerizing a mixture comprising a first polymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and optionally a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary hydroxyl and/or amino group(s) and a second polymerizable organic moiety, for obtaining an water-soluble polymer; a step of coupling to the water-soluble polymer a compound having a olymerizable moiety and a functional group reactive with an optionally protected carboxylic acid group of repeating units derived from the first polymerizable monomer or an optionally protected hydroxyl and/or amino group of repeating units derived from the second copolymerizable monomer in the water-soluble polymer obtained in step a), wherein the optionally protected carboxylic acid group and the optionally protected hydroxyl and/or amine group are deprotected, so that polymerizable pendant groups are linked to the backbone by ester groups, urethane groups and/or amide groups, and, optionally, a step of deprotecting the protected carboxylic acid group for obtaining a polymerizable polymer.