公开(公告)号：US11859010B2

公开(公告)日：2024-01-02

申请号：US17930143

申请日：2022-09-07

申请人： CytomX Therapeutics, Inc.

发明人： Leila Marie Boustany ,  Sherry L. La Porte ,  Bryan A. Irving ,  Jeanne Grace Flandez

IPC分类号： G01N31/00 ,  G01N33/53 ,  C07K16/40 ,  C07K16/28 ,  A61P35/00 ,  C12N15/62 ,  A61K39/00

CPC分类号： C07K16/40 ,  A61P35/00 ,  C07K16/2809 ,  C07K16/2863 ,  C12N15/62 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/52 ,  C07K2317/622 ,  C07K2317/64 ,  C07K2317/71 ,  C07K2317/73

摘要： Provided herein antibodies, activatable antibodies (AAs), bispecific antibodies, and bispecific activatable antibodies (BAAs). Also provided herein are methods of making and methods of use of these antibodies, AAs, bispecific antibodies, and BAAs.

公开(公告)号：US20190135943A1

公开(公告)日：2019-05-09

申请号：US16159451

申请日：2018-10-12

申请人： CytomX Therapeutics, Inc.

发明人： Leila Marie Boustany ,  Sherry L. La Porte ,  Bryan A. Irving ,  Jeanne Grace Flandez

IPC分类号： C07K16/40 ,  A61P35/00 ,  C12N15/62

摘要： Provided herein antibodies, activatable antibodies (AAs), bispecific antibodies, and bispecific activatable antibodies (BAAs). Also provided herein are methods of making and methods of use of these antibodies, AAs, bispecific antibodies, and BAAs.

公开(公告)号：US11472889B2

公开(公告)日：2022-10-18

申请号：US16159451

申请日：2018-10-12

申请人： CytomX Therapeutics, Inc.

发明人： Leila Marie Boustany ,  Sherry L. La Porte ,  Bryan A. Irving ,  Jeanne Grace Flandez

IPC分类号： G01N31/00 ,  G01N33/53 ,  C07K16/40 ,  C07K16/28 ,  A61P35/00 ,  C12N15/62 ,  A61K39/00

摘要： Provided herein antibodies, activatable antibodies (AAs), bispecific antibodies, and bispecific activatable antibodies (BAAs). Also provided herein are methods of making and methods of use of these antibodies, AAs, bispecific antibodies, and BAAs.