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    STABILIZATION OF RESORCINOL COMPOUNDS IN COSMETIC COMPOSITIONS
    3.
    发明申请
    STABILIZATION OF RESORCINOL COMPOUNDS IN COSMETIC COMPOSITIONS 有权

    公开(公告)号：US20220362120A1

    公开(公告)日：2022-11-17

    申请号：US17623394

    申请日：2020-06-23

    申请人： Conopco, Inc., d/b/a UNILEVER

    发明人： Jose Guillermo ROSA ,  Teanoosh MOADDEL

    IPC分类号： A61K8/34 ,  A61K8/44 ,  A61Q19/02

    摘要： Topical cosmetic compositions containing a 4-substituted resorcinol derivative along with N-acetyl methionine exhibit improved storage stability and oxidative stability. A method of stabilizing 4-ethyl resorcinol or 4-hexyl resorcinol in a composition comprising a cosmetically acceptable vehicle by adding to the composition Acetyl Methionine in an amount sufficient to stabilize said 4-ethyl resorcinol or 4-hexyl resorcinol. Use of the N-Acetyl Methionine and stabilized 4-substituted resorcinol derivatives in the manufacture of a topical cosmetic composition.

    PROCESS OF MAKING N,N'-DIACETYL-L-CYSTINE
    7.
    发明公开
    PROCESS OF MAKING N,N'-DIACETYL-L-CYSTINE 审中-公开

    公开(公告)号：US20230183176A1

    公开(公告)日：2023-06-15

    申请号：US17919908

    申请日：2021-04-14

    申请人： Conopco, Inc., d/b/a UNILEVER

    发明人： Jose Guillermo ROSA ,  Bijan HARICHIAN

    IPC分类号： C07C323/59

    CPC分类号： C07C323/59

    摘要： An effective process of making N,N′-diacetyl-L-Cystine (“NDAC”), which process is fast, green, does not require labor-intensive isolation or purification of the product, by yielding products in desired ratio, and has improved yield and purity. The process comprising the steps of Forming a reaction mixture, starting with a cystine derivative di-tert- butyl-L-cystine as the dihydrochloride form; Acetylating said di-tert-butyl-L-cystine to obtain N,N′-diacetyl-di-tert- butyl-L-cystine; followed by Removing said tert- butyl groups from said N,N′-diacetyl-di-tert-butyl- L-cystine to obtain N,N′-diacetyl-L-cystine product; and Isolating said N,N′-diacetyl-L-Cystine product from said reaction mixture; wherein said acetylating agent is acetic anhydride.

    BIOENERGETIC COMBINATIONS AND METHODS OF USING SAME
    9.
    发明申请
    BIOENERGETIC COMBINATIONS AND METHODS OF USING SAME 有权

    公开(公告)号：US20220362127A1

    公开(公告)日：2022-11-17

    申请号：US17623390

    申请日：2020-06-23

    申请人： Conopco, Inc., d/b/a UNILEVER

    发明人： Sheila Alves ROCHA ,  Chung-Yi CHIANG ,  Jose Guillermo ROSA ,  John Chun-Sing NIP

    IPC分类号： A61K8/67 ,  A61Q19/08 ,  A61K8/46

    摘要： Topical personal care compositions for improving cellular energy efficiency by protecting skin from mitochondrial fragmentation that takes place in the cells of an aging individual in need thereof. Use of a topical personal care composition comprising niacinamide and of one or more cooperative skin benefit agents for reducing cellular mitochondrial fragmentation, which cooperative agents are selected from the group consisting of 1-methylnicotinamide chloride, N-acetylmethionine, mixtures thereof, and derivatives thereof. Use of niacinamide and cooperative skin benefit agent selected from 1-methylnicotinamide chloride, N-acetylmethionine, mixtures thereof, and derivatives thereof in the manufacture of a topical personal care composition for decreasing or preventing mitochondrial fragmentation in skin cells and for increasing skin cellular energy.