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公开(公告)号:US20200113794A1
公开(公告)日:2020-04-16
申请号:US16708646
申请日:2019-12-10
发明人: Aarti REGE , Michael PRENCIPE
摘要: An oral care composition comprising high water oral care compositions comprising an orally acceptable carrier, zinc phosphate, a first stannous ion source (i.e., stannous fluoride), and a second stannous ion source (i.e., stannous chloride). Methods and uses for this composition are also described throughout.
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公开(公告)号:US20190336417A1
公开(公告)日:2019-11-07
申请号:US16515182
申请日:2019-07-18
发明人: Kavita VEMISHETTI , Linh FRUGE , Michael PRENCIPE
摘要: The present disclosure provides low water dentifrice compositions comprising an effective amount of a zinc ion source, a stannous ion source, a polyphosphate and an acid in a calcium pyrophosphate base. The acid lowers the pH of the composition to enable stabilization of the metal ions and extend shelf-life of the composition.
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公开(公告)号:US20180221259A1
公开(公告)日:2018-08-09
申请号:US15749541
申请日:2017-06-23
发明人: Andrei POTANIN , Tilo POTH , Amit AHUJA , Claude BLANVALET , Betty WON , Lisa MANUS , Michael STRANICK , Xiao Yi HUANG , Michael PRENCIPE , Amy RUSSO , Hansruedi STETTLER , Peng YAN , Chengkang TAN , Vyoma PATEL , Andre MORGAN
CPC分类号: A61K8/44 , A61K8/042 , A61K8/21 , A61K8/24 , A61K8/25 , A61K8/27 , A61K8/34 , A61K8/365 , A61K8/37 , A61K8/442 , A61K8/73 , A61K8/731 , A61K2800/28 , A61K2800/48 , A61K2800/52 , A61Q11/00
摘要: Described herein are oral care compositions comprising a basic amino acid; a combination of zinc ion sources; and a thickening system comprising a nonionic cellulose ether having a viscosity, measured at 2% in water at 25° C., of 4500 to 7500 cps; and a polysaccharide gum; along with methods of making and using same.
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公开(公告)号:US20180168977A1
公开(公告)日:2018-06-21
申请号:US15674034
申请日:2017-08-10
发明人: Aarti REGE , Michael PRENCIPE , Marc ESTRIPLET
摘要: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.
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公开(公告)号:US20180168956A1
公开(公告)日:2018-06-21
申请号:US15708556
申请日:2017-09-19
发明人: Aarti REGE , Michael PRENCIPE , Paul THOMSON
CPC分类号: A61K8/24 , A61K8/19 , A61K8/21 , A61K8/27 , A61K8/345 , A61K8/362 , A61K8/365 , A61K8/8164 , A61Q11/00
摘要: This invention relates to oral care compositions comprising a zinc source comprising zinc oxide and zinc citrate; a stannous source comprising stannous pyrophosphate; a fluoride ion source comprising sodium fluoride; and an organic buffer, as well as to methods of using and of making these compositions.
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公开(公告)号:US20180015016A1
公开(公告)日:2018-01-18
申请号:US15548468
申请日:2016-06-24
发明人: Xiaoyi HUANG , Michael PRENCIPE , Amy RUSSO , Hansruedi STETTLER , Vyoma PATEL , Betty WON , Peng YAN , Andre MORGAN
CPC分类号: A61K8/44 , A61K8/21 , A61K8/25 , A61K8/27 , A61K8/345 , A61K8/362 , A61K8/365 , A61K2800/28 , A61K2800/92 , A61Q11/00
摘要: An oral care composition comprises arginine or lysine, zinc citrate and zinc oxide, a fluoride source, and glycerin, as well as to methods of using and of making the composition.
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公开(公告)号:US20170367953A1
公开(公告)日:2017-12-28
申请号:US15629097
申请日:2017-06-21
发明人: Dandan Chen , Ying YANG , Robert D'AMBROGIO , Paul THOMSON , Harsh Mahendra TRIVEDI , Michael PRENCIPE , James MASTERS , Stanislav JARACZ
摘要: This invention relates to oral care compositions comprising zingerone, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.
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公开(公告)号:US20170128329A1
公开(公告)日:2017-05-11
申请号:US15320093
申请日:2014-06-20
发明人: Kavita VEMISHETTI , Linh FRUGE , Michael PRENCIPE
摘要: An oral care composition containing a stannous ion source, a zinc ion source, a polyphosphate, and a thickening agent. The thickening agent contains polyvinylpyrrolidone, a polysaccharide gum and carboxymethyl cellulose. The compositions have excellent rheology properties.
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公开(公告)号:US20220331211A1
公开(公告)日:2022-10-20
申请号:US17853788
申请日:2022-06-29
发明人: Aarti REGE , Michael PRENCIPE , Madhuleena BHADRA
摘要: An oral care composition comprising zinc phosphate, stannous fluoride and an organic acid buffer system, as well as methods of using the same.
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公开(公告)号:US20210244633A1
公开(公告)日:2021-08-12
申请号:US17302084
申请日:2021-04-23
发明人: James BROWN , Linh FRUGE , Tao XU , Michael PRENCIPE
IPC分类号: A61K8/21 , A61K8/03 , A61K8/19 , A61K8/20 , A61K8/24 , A61K8/81 , A61Q11/00 , A61K8/55 , A61K8/69 , A61K8/25
摘要: Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1% of the compositions. Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) immediately prior to dental care usage.
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