公开(公告)号：US11668653B2

公开(公告)日：2023-06-06

申请号：US15776649

申请日：2016-11-16

Applicant: ChemImage Corporation

Inventor： Patrick Treado ,  Shona Stewart ,  Aaron Smith ,  Heather Gomer

IPC: G01N21/65 ,  G01J3/44 ,  G01N21/17 ,  G01J3/02 ,  G01J3/28 ,  G16H50/20 ,  G01N33/53

CPC classification number: G01N21/65 ,  G01J3/0218 ,  G01J3/0291 ,  G01J3/2823 ,  G01J3/44 ,  G01N21/17 ,  G01N33/53 ,  G16H50/20 ,  G01N2201/0833 ,  G01N2800/50 ,  G01N2800/52 ,  G01N2800/56 ,  G01N2800/60

Abstract: This disclosure is directed to systems and methods for fusing Raman data with biomarker data to identify a disease and/or the progression of the disease. The system disclosed herein may include an illumination source for generating interacted photons from a biological sample and a detector for detecting the interacted photons to generate a Raman data set. A processor is included to fuse the Raman data set with a biomarker data set to identify a disease and/or a disease progression. The instant disclosure further includes a method comprising illuminating a biological sample to generate interacted photons, and detecting the interacted photons to generate a Raman data set. A biomarker data set is obtained from the biological sample, and the Raman data set is fused with the biomarker data set to generate an index score. The index score correlates with one or more of a disease and a disease progression.

公开(公告)号：US12295743B2

公开(公告)日：2025-05-13

申请号：US16781610

申请日：2020-02-04

Applicant: CHEMIMAGE CORPORATION

Inventor： Jeffrey K. Cohen ,  J. Christopher Post ,  Shona Stewart ,  Patrick J. Treado ,  Heather Gomer ,  Aaron Smith

IPC: A61B5/00 ,  G01J3/02 ,  G01J3/28 ,  G01J3/42

Abstract: Systems and methods of detecting and monitoring edema in a subject are described. The systems and methods include light sources, image detectors, filters, and processors that determine whether a subject has edema and the degree of severity. In some embodiments, the processor fuses data from more than one imaging modality.

公开(公告)号：US11980349B2

公开(公告)日：2024-05-14

申请号：US16244845

申请日：2019-01-10

Applicant: CHEMIMAGE CORPORATION

Inventor： Patrick Treado ,  Charles Gardner ,  Shona Stewart ,  Aaron Smith

IPC: A61B1/05 ,  A61B1/00 ,  A61B1/04 ,  A61B1/06 ,  A61B1/07 ,  H04N23/11 ,  H04N23/45 ,  H04N23/55 ,  H04N23/56 ,  H04N23/50

CPC classification number: A61B1/051 ,  A61B1/0005 ,  A61B1/00096 ,  A61B1/00167 ,  A61B1/046 ,  A61B1/0607 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0676 ,  A61B1/07 ,  H04N23/11 ,  H04N23/45 ,  H04N23/55 ,  H04N23/56 ,  A61B1/00009 ,  H04N23/555

Abstract: An endoscope has an improved chip-on-tip configuration that includes both a first configuration of source illumination fibers and a second plurality of source illumination fibers, along with a camera chip. The combination of the camera chip and the source illumination fibers on the tip of the endoscope results in endoscopes with reduced size and weight.