公开(公告)号：US20240270825A1

公开(公告)日：2024-08-15

申请号：US18237817

申请日：2023-08-24

Applicant: Centivax, Inc.

Inventor： Jacob Glanville ,  Shahrad Daraeikia ,  I-Chieh Wang ,  Sindy Andrea Liao Chan ,  Jean-Philippe Bürckert ,  Sawsan Youssef

IPC: C07K16/10 ,  A61P31/14 ,  G01N33/569

CPC classification number: C07K16/1003 ,  A61P31/14 ,  G01N33/56983 ,  C07K2317/622 ,  C07K2317/76 ,  C07K2317/92 ,  G01N2333/165 ,  G01N2469/10

Abstract: This disclosure provides antibodies and that can be administered to an individual that is infected with a virus. Antibodies herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to several weeks. Antibodies herein can be used to diagnose a SARS-CoV-2 infection.

公开(公告)号：US20240294618A1

公开(公告)日：2024-09-05

申请号：US18481129

申请日：2023-10-04

Applicant: Centivax, Inc.

Inventor： Jacob E. Glanville ,  Timothy Paul Friede ,  David Tsao ,  Sindy Andrea Liao Chan ,  I-Chieh Wang

IPC: C07K16/18 ,  A61K31/404 ,  A61K39/00 ,  A61P39/02 ,  G01N33/68

CPC classification number: C07K16/18 ,  A61K31/404 ,  A61P39/02 ,  G01N33/6857 ,  A61K2039/505 ,  C07K2317/565 ,  C07K2317/76 ,  G01N2333/4616 ,  G01N2333/4646

Abstract: This disclosure provides antibodies and antigen-binding fragments that can be administered to a subject that has been bitten by a venomous snake. Antibodies and antigen-binding fragments herein can be capable of treating or curing the subject and may provide protection against snake venom for up to several weeks. A combination or population of antibodies and antigen-binding fragments can be administered to the subject where the type of snake is not known or where a subject has been bitten by more than one species of snake. This disclosure further provides methods for identification of such broadly-neutralizing antibodies.

公开(公告)号：US11028150B1

公开(公告)日：2021-06-08

申请号：US15931642

申请日：2020-05-14

Applicant: Centivax, Inc.

Inventor： Jacob Glanville ,  Shahrad Daraeikia ,  I-Chieh Wang ,  Sindy Andrea Liao Chan ,  Jean-Philippe Bürckert ,  Sawsan Youssef

IPC: C07K16/10 ,  A61K39/42 ,  G01N33/569 ,  A61P31/14 ,  A61K39/00

Abstract: This disclosure provides antibodies and antigen-binding fragments that are derived from 2dd8 and that can be administered to an individual that is infected or suspected of being infected with a virus. Antibodies and antigen-binding fragments herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to several weeks. Antibodies and antigen-binding fragments herein can be used to diagnose a SARS CoV-2 infection.

公开(公告)号：US20230272051A1

公开(公告)日：2023-08-31

申请号：US17934785

申请日：2022-09-23

Applicant: Centivax, Inc.

Inventor： Jacob Glanville ,  Shahrad Daraeikia ,  I-Chieh Wang ,  Sindy Andrea Liao Chan ,  Jean-Philippe Bürckert ,  Sawsan Youssef

IPC: C07K16/10

CPC classification number: C07K16/1018 ,  C07K2317/565

Abstract: This disclosure provides antibodies and antigen-binding fragments that can be administered to an individual that is infected or suspected of being infected with a virus. Antibodies and antigen-binding fragments herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to several weeks. Antibodies and antigen-binding fragments herein can be used to diagnose a SARS-CoV-2 infection.

公开(公告)号：US11053304B1

公开(公告)日：2021-07-06

申请号：US15931648

申请日：2020-05-14

Applicant: Centivax, Inc.

Inventor： Jacob Glanville ,  Shahrad Daraeikia ,  I-Chieh Wang ,  Sindy Andrea Liao-Chan ,  Jean-Philippe Bürckert ,  Sawsan Youssef

IPC: C07K16/10 ,  A61K39/42 ,  G01N33/569 ,  A61P31/14 ,  A61K39/00

Abstract: This disclosure provides antibodies and antigen-binding fragments that are derived from 6nb6 and that can be administered to an individual that is infected or suspected of being infected with a virus. Antibodies and antigen-binding fragments herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to several weeks. Antibodies and antigen-binding fragments herein can be used to diagnose a SARS CoV 2 infection.

公开(公告)号：US11034762B1

公开(公告)日：2021-06-15

申请号：US15931649

申请日：2020-05-14

Applicant: Centivax, Inc.

Inventor： Jacob Glanville ,  Shahrad Daraeikia ,  I-Chieh Wang ,  Sindy Andrea Liao Chan ,  Jean-Philippe Bürckert ,  Sawsan Youssef

IPC: A61K39/42 ,  C07K16/28 ,  G01N33/569 ,  C07K16/10 ,  A61K39/00

Abstract: This disclosure provides antibodies that are derived from CFR3022 and that can be administered to an individual that is infected with a virus. Antibodies herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to several weeks. Antibodies herein can be used to diagnose a SARS CoV 2 infection.

公开(公告)号：US11028167B1

公开(公告)日：2021-06-08

申请号：US15931652

申请日：2020-05-14

Applicant: Centivax, Inc.

Inventor： Jacob Glanville ,  Shahrad Daraeikia ,  I-Chieh Wang ,  Sindy Andrea Liao Chan ,  Jean-Philippe Bürckert ,  Sawsan Youssef

IPC: C07K16/28 ,  C07K16/10 ,  G01N33/569 ,  A61K39/00

Abstract: This disclosure provides antibodies and antigen-binding fragments that are derived from 3bgf and that can be administered to an individual that is infected or suspected of being infected with a virus. Antibodies and antigen-binding fragments herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to several weeks. Antibodies and antigen-binding fragments herein can be used to diagnose a SARS CoV-2 infection.

公开(公告)号：US11021532B1

公开(公告)日：2021-06-01

申请号：US15931654

申请日：2020-05-14

Applicant: Centivax, Inc.

Inventor： Jacob Glanville ,  Shahrad Daraeikia ,  I-Chieh Wang ,  Sindy Andrea Liao-Chan

IPC: A61K39/42 ,  C07K16/10 ,  G01N33/68 ,  A61P31/14 ,  A61K39/00 ,  A61K45/06

Abstract: This disclosure provides superhuman antibodies and antigen-binding fragments that can be administered to an individual that is infected or suspected of being infected with a virus. Superhuman antibodies and antigen-binding fragments provided herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to at least several weeks. Superhuman antibodies and antigen-binding fragments provided herein can be used to diagnose a SARS Cov-2 infection.

公开(公告)号：US11021531B1

公开(公告)日：2021-06-01

申请号：US15931643

申请日：2020-05-14

Applicant: Centivax, Inc.

Inventor： Jacob Glanville ,  Shahrad Daraeikia ,  I-Chieh Wang ,  Sindy Andrea Liao-Chan ,  Jean-Philippe Bürckert ,  Sawsan Youssef

IPC: A61K39/42 ,  C07K16/10 ,  A61P31/14 ,  A61K39/00

Abstract: This disclosure provides antibodies and antigen-binding fragments that are derived from 2ghw and that can be administered to an individual that is infected or suspected of being infected with a virus. Antibodies and antigen-binding fragments provided herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to several weeks. Antibodies and antigen-binding fragments provided herein can be used to diagnose a SARS-Cov-2 infection.