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1.发明授权Methods, devices and systems for cardiac rhythm management using an electrode arrangement 有权使用电极装置进行心律管理的方法，装置和系统公开(公告)号：US09008768B2
公开(公告)日：2015-04-14
申请号：US13862776
申请日：2013-04-15
CPC分类号： A61N1/371 , A61N1/3627
摘要： Various embodiments of the present invention are directed to systems, methods and devices for cardiac applications. One such device is directed to a catheter, and uses thereof, for capturing myocardium of a heart by delivering pacing signals to a location in the heart. The location is near a His Bundle of the heart. The catheter has a proximal end for interfacing with an electrical pacing signal source and a distal end. The distal end includes a fixation mechanism that attaches the catheter to heart tissue. First and second electrodes are also located at the distal end. Each electrode is individually addressable for providing pacing signals to the heart tissue and also arranged to physically contact the heart tissue when the fixation mechanism is attached to the heart tissue.
摘要翻译： 本发明的各种实施例涉及用于心脏应用的系统，方法和装置。 一种这样的装置被引导到导管并用于通过将起搏信号传送到心脏中的位置来捕获心脏的心肌。 位置靠近他的心脏的束缚。 导管具有用于与电起搏信号源和远端接合的近端。 远端包括将导管附接到心脏组织的固定机构。 第一和第二电极也位于远端。 每个电极单独地可寻址以用于向心脏组织提供起搏信号，并且还布置成当固定机构附接到心脏组织时物理接触心脏组织。
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2.发明申请ADVANCED PATIENT MANAGEMENT FOR DEFINING, IDENTIFYING AND USING PREDETERMINED HEALTH-RELATED EVENTS 有权定义，鉴定和使用预防性健康相关活动的高级患者管理公开(公告)号：US20130158416A1
公开(公告)日：2013-06-20
申请号：US13769737
申请日：2013-02-18
IPC分类号： A61B5/0205
CPC分类号： A61B5/0205 , A61N1/08
摘要： Systems, devices and methods for defining, identifying and using health-related significant events are disclosed. One aspect is a programmable device having machine executable instructions for performing a method to assist with managing a patient's health. In various embodiments, at least one previously-defined event is detected based on a number of acquired health-related parameters. The at least one detected event is recorded with an associated time when the at least one detected significant event occurred. An action is triggered based on the at least one detected event. The at least one detected event is displayed with at least one trended health-related parameter in a single display area. Other aspects and embodiments are provided herein.
摘要翻译： 公开了用于定义，识别和使用健康相关重要事件的系统，设备和方法。 一个方面是具有用于执行帮助管理患者健康的方法的机器可执行指令的可编程设备。 在各种实施例中，基于所获取的健康相关参数的数量来检测至少一个先前定义的事件。 当发生至少一个检测到的有害事件时，相关联的时间记录至少一个检测到的事件。 基于至少一个检测到的事件触发动作。 至少一个检测到的事件在单个显示区域中与至少一个趋势健康相关的参数显示。 本文提供了其它方面和实施例。
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公开(公告)号：US20170035297A1
公开(公告)日：2017-02-09
申请号：US15332609
申请日：2016-10-24
CPC分类号： A61B5/0031 , A61B5/0022 , A61B5/0205 , A61B5/0537 , A61B5/0816 , A61B5/091 , A61B5/1118 , A61B7/04 , A61B2560/0247 , A61B2560/0252 , A61B2560/0257 , A61N1/37252 , A61N1/37282 , G06F19/00 , G06F19/3418 , G16H40/63 , G16H50/30
摘要： Systems, devices and methods for using environmental data to manage health care are disclosed. One aspect is an advanced patient management system. In various embodiments, the system includes at least one implantable medical device (IMD) to acquire at least one IMD parameter indicative of patient wellness, means to acquire at least one environmental parameter from at least one external source, and means to correlate the at least one parameter indicative of patient wellness and the at least one environmental parameter to assist with patient health care decisions. Other aspects and embodiments are provided herein.
摘要翻译： 公开了使用环境数据来管理医疗保健的系统，设备和方法。 一个方面是先进的患者管理系统。 在各种实施例中，系统包括至少一个可植入医疗装置（IMD），以获取指示患者健康的至少一个IMD参数，从至少一个外部源获取至少一个环境参数的手段，以及至少将 指示患者健康的一个参数和用于协助患者医疗保健决定的至少一个环境参数。 本文提供了其它方面和实施例。
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4.发明授权Endocardial pacing devices and methods useful for resynchronization and defibrillation 有权用于再同步和除颤的心内起搏装置和方法公开(公告)号：US09031648B2
公开(公告)日：2015-05-12
申请号：US14029588
申请日：2013-09-17
CPC分类号： A61N1/3962 , A61N1/3627
摘要： According to one aspect, various methods and apparatus are used for treating a condition of a patient's heart, and for monitoring cardiac operation. In one approach consistent therewith, an electrode arrangement is placed in a right ventricle of the heart. The electrode arrangement is used to capture the myocardium for re-synchronization of the left and right ventricles by providing first and second signal components having opposite polarity on respective electrodes. The electrode arrangement is connected to an implantable CRM device that has the capability of pacing/sensing atrium, pacing/sensing ventricles, and deliver defibrillation therapy from the right side of the heart. The CRM device captures ventricular contractions to treat conduction abnormalities in one or more of the ventricles.
摘要翻译： 根据一个方面，使用各种方法和装置来治疗患者心脏的状况，并用于监测心脏手术。 在与其一致的一种方法中，将电极装置放置在心脏的右心室中。 电极装置用于通过在相应的电极上提供具有相反极性的第一和第二信号分量来捕获心肌以重新同步左心室和右心室。 电极装置连接到具有起搏/感测心房，起搏/感测心室的能力的可植入CRM装置，并且从心脏的右侧输送除颤疗法。 CRM设备捕获心室收缩以治疗一个或多个心室中的传导异常。
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公开(公告)号：US08934969B2
公开(公告)日：2015-01-13
申请号：US14027568
申请日：2013-09-16
CPC分类号： A61N1/36592 , A61N1/3627
摘要： Various systems, methods, devices and arrangements are implemented for use in pacing of the heart. One implementation is directed to methods and systems for determining a pacing location in the right ventricle of a heart and near the His bundle. A pacing signal is delivered to the location in the right ventricle. The pacing signal produces a capture of a left ventricle. Properties of the capture are monitored. Results of the monitored capture are used to assess the effectiveness of the delivered pacing signal as a function of heart function. The heart function can be, for example, at least one of a QRS width, fractionation and a timing of electrical stimulation of a late activation site of a left ventricle relative to the QRS.
摘要翻译： 实施各种系统，方法，装置和布置以用于心脏起搏。 一种实现涉及用于确定心脏右心室和His束附近的起搏位置的方法和系统。 起搏信号传送到右心室的位置。 起搏信号产生左心室的捕获。 捕获的属性被监视。 监测捕获的结果用于评估所输送的起搏信号作为心脏功能的函数的有效性。 心脏功能可以是例如左心室相对于QRS的晚期激活部位的QRS宽度，分割和电刺激的定时中的至少一个。
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6.发明授权Methods, devices and systems for single-chamber pacing using a dual-chamber pacing device 有权使用双室起搏装置的单室起搏方法，装置和系统公开(公告)号：US08903489B2
公开(公告)日：2014-12-02
申请号：US13650444
申请日：2012-10-12
CPC分类号： A61N1/3627 , A61N1/3752
摘要： Various embodiments of the present invention are directed to systems, methods and devices for cardiac applications including those relating to pacing devices. One such device is directed to a cardiac rhythm therapy (CRT) device designed for dual chamber pacing using two pacing signals each having a positive and negative component that has been modified for single chamber pacing. The device comprises a first output that connects to a pacing lead; a second output that connects to the pacing lead; a third output that connects to a reference point; and electrical circuitry connecting the second electrical connection to the first output, the third electrical connection to the second output, and the first and fourth electrical connections to the third output.
摘要翻译： 本发明的各种实施例涉及用于心脏应用的系统，方法和装置，包括与起搏装置相关的那些。 一种这样的装置被引导到设计用于双室起搏的心律治疗（CRT）装置，其使用两个起搏信号，每个起搏信号具有已被修改用于单室起搏的正和负分量。 该装置包括连接到起搏引线的第一输出端; 连接到起搏引线的第二输出; 连接到参考点的第三输出; 以及将第二电连接与第一输出连接的电路，到第二输出的第三电连接以及到第三输出的第一和第四电连接。
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7.发明授权Devices and methods for steering electrical stimulation in cardiac rhythm management 有权用于在心律管理中转向电刺激的装置和方法公开(公告)号：US08825159B2
公开(公告)日：2014-09-02
申请号：US13688859
申请日：2012-11-29
IPC分类号： A61N1/362
CPC分类号： A61N1/37 , A61N1/3627
摘要： Tools and methods are particularly suited for certain cardiac conditions involving use of a catheter for pacing of the right and left ventricles from a lead in the right ventricle, e.g., to facilitate mechanically and/or electrically synchronous contractions for resynchronization. Certain aspects involve pacing and/or mapping by delivering pulses to a cardiac site useful for improving heart function as measured, e.g., by QRS width, fractionation, late LV activation timing, mechanical synchronicity of free wall and septal wall, effective throughput/pressure, or a combination thereof. In one embodiment, a catheter arrangement includes a fixation mechanism to attach the catheter arrangement to heart tissue, individually-addressable electrodes for providing pacing signals to the heart tissue, and an elongated structure that supports the fixation mechanism and the electrodes. The elongated structure is used to direct an end thereof to the target region in the right ventricle, and deliver an electrical pacing signal to different portions within the target region of the heart when the fixation mechanism is operative to attach to heart tissue and also when the fixation mechanism is not attaching the catheter arrangement to heart tissue.
摘要翻译： 工具和方法特别适合于某些心脏状况，包括使用导管将右心室和左心室从右心室中的引线起搏，例如为了促进用于再同步的机械和/或电同步收缩。 某些方面涉及通过将脉搏递送到心脏位置，用于改善心脏功能，例如通过QRS宽度，分级，晚期LV激活时间，游离壁和间隔壁的机械同步性，有效吞吐量/压力， 或其组合。 在一个实施例中，导管装置包括用于将导管装置附接到心脏组织的固定机构，用于向心脏组织提供起搏信号的单独寻址电极，以及支撑固定机构和电极的细长结构。 细长结构用于将其末端引导到右心室中的目标区域，并且当固定机构可操作地附接到心脏组织时，以及当心脏组织工作时，将电起搏信号递送到心脏的目标区域内的不同部分 固定机构不将导管装置附接到心脏组织。
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公开(公告)号：US20150088005A1
公开(公告)日：2015-03-26
申请号：US14559069
申请日：2014-12-03
发明人： Avram Scheiner , Qingsheng Zhu , Arthur L. Olive , Don Villalta
IPC分类号： A61B7/04 , A61B5/00 , A61B5/11 , A61B5/0402 , A61B5/04
CPC分类号： A61B7/04 , A61B5/0002 , A61B5/0031 , A61B5/04012 , A61B5/04014 , A61B5/0402 , A61B5/042 , A61B5/044 , A61B5/0452 , A61B5/1118 , A61B5/742 , A61B7/00 , A61B7/023
摘要： An apparatus for outputting heart sounds includes an implantable system and an external system. The implantable system includes a sensor for generating sensed signals representing detected heart sounds, an interface circuit and a control circuit for receiving the sensed signals, generating data representing the heart sounds therefrom, and transmitting the data to the external system via the interface circuit. The external system includes an interface circuit for communicating with the implantable system, and a control circuit for receiving the data representing the heart sounds and for generating control signals that cause an output device to generate outputs representing the sounds. The implantable system may also include a sensor(s) for detecting cardiac electrical signals. in this case, outputs representing the cardiac electrical signals are also output.
摘要翻译： 用于输出心音的装置包括可植入系统和外部系统。 可植入系统包括用于产生表示检测到的心音的感测信号的传感器，接口电路和用于接收感测信号的控制电路，产生表示心音的数据，以及经由接口电路将数据发送到外部系统。 外部系统包括用于与可植入系统进行通信的接口电路，以及用于接收表示心脏声音的数据的控制电路，以及用于产生使输出设备产生表示声音的输出的控制信号。 可植入系统还可以包括用于检测心脏电信号的传感器。 在这种情况下，也输出表示心电信号的输出。
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公开(公告)号：US08838238B2
公开(公告)日：2014-09-16
申请号：US13645464
申请日：2012-10-04
IPC分类号： A61N1/362
CPC分类号： A61N1/371 , A61N1/362 , A61N1/3627 , A61N1/3962
摘要： A method and apparatus are disclosed for treating a condition of a patient's heart includes placing a first electrode and/or a second electrode in a right ventricle of the heart. In one example, a reference electrode is placed within the patient and internal or external to the heart. A pacing signal is generated including a first signal component, a second signal component and a reference component with the first and second signal components having opposite polarity and with both of the first and second components having a potential relative to the reference component. The pacing signal and the placement of the electrodes are selected to alter a contraction of a left ventricle of the heart.
摘要翻译： 公开了一种用于治疗患者心脏状况的方法和装置，包括将第一电极和/或第二电极放置在心脏的右心室中。 在一个示例中，将参考电极放置在患者体内并在心脏内部或外部。 生成包括第一信号分量，第二信号分量和参考分量的起搏信号，其中第一和第二信号分量具有相反的极性，并且第一和第二分量都具有相对于参考分量的电势。 选择起搏信号和放置电极以改变心脏左心室的收缩。
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公开(公告)号：US20140073980A1
公开(公告)日：2014-03-13
申请号：US14080454
申请日：2013-11-14
发明人： Avram Scheiner , Qingsheng Zhu , Arthur L. Olive , Don Villalta
CPC分类号： A61B7/04 , A61B5/0002 , A61B5/0031 , A61B5/04012 , A61B5/04014 , A61B5/0402 , A61B5/042 , A61B5/044 , A61B5/0452 , A61B5/1118 , A61B5/742 , A61B7/023 , G06F19/00
摘要： An apparatus for outputting heart sounds includes an implantable system and an external system. The implantable system includes a sensor for generating sensed signals representing detected heart sounds, an interface circuit and a control circuit for receiving the sensed signals, generating data representing the heart sounds therefrom, and transmitting the data to the external system via the interface circuit. The external system includes an interface circuit for communicating with the implantable system, and a control circuit for receiving the data representing the heart sounds and for generating control signals that cause an output device to generate outputs representing the sounds. The implantable system may also include a sensor(s) for detecting cardiac electrical signals. In this case, outputs representing the cardiac electrical signals are also output.
摘要翻译： 用于输出心音的装置包括可植入系统和外部系统。 可植入系统包括用于产生表示检测到的心音的感测信号的传感器，接口电路和用于接收感测信号的控制电路，产生表示心音的数据，以及经由接口电路将数据发送到外部系统。 外部系统包括用于与可植入系统进行通信的接口电路，以及用于接收表示心脏声音的数据的控制电路，以及用于产生使输出设备产生表示声音的输出的控制信号。 可植入系统还可以包括用于检测心脏电信号的传感器。 在这种情况下，还输出表示心电信号的输出。
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