FLOW CELLS WITH STABLE POLYMER COATING AND THEIR USES FOR GENE SEQUENCING

    公开(公告)号:US20210301335A1

    公开(公告)日:2021-09-30

    申请号:US17266245

    申请日:2019-08-05

    摘要: A flow cell article is provided where the flow cell article includes a substrate having one or more layers; a fluidic channel disposed in the substrate wherein the fluidic channel includes at least one reactive surface comprising: a coupling agent having a first functional group covalently attached to the substrate of the fluidic channel and a second imide functional group covalently attached to a polymer of formula (I), where R1 is a residue of an unsaturated monomer that has been copolymerized with maleic anhydride; R2 is H, an alkyl group, an oligo(ethylene glycol), and/or a dialkyl amine; m, n, and o are each from 1 to 10,000; X is a divalent NH, O, and/or S; and Z is the first functional group.

    FLOW CELLS HAVING REACTIVE SURFACES FOR NUCLEIC ACID SEQUENCE ANALYSIS

    公开(公告)号:US20190085390A1

    公开(公告)日:2019-03-21

    申请号:US16127617

    申请日:2018-09-11

    IPC分类号: C12Q1/6874

    摘要: A flow cell article including: a chamber; and at least one surface of the chamber comprising: a solid substrate having a reactive surface comprising: a coupling agent covalently attached to the solid substrate; a polymer of the formula (I) as defined herein, covalently attached to the coupling agent; anda nucleic acid probe covalently attached to the polymer. Also disclosed is a method of making the article and a method of using the article.

    ANTIMICROBIAL ARTICLES WITH SILVER-CONTAINING ALKALI SILICATE COATING AND METHODS OF MAKING THEREOF
    9.
    发明申请
    ANTIMICROBIAL ARTICLES WITH SILVER-CONTAINING ALKALI SILICATE COATING AND METHODS OF MAKING THEREOF 审中-公开
    具有含银碱金属硅酸盐涂料的抗微生物物品及其制备方法

    公开(公告)号:US20170036949A1

    公开(公告)日:2017-02-09

    申请号:US15305155

    申请日:2015-04-22

    IPC分类号: C03C17/25 C03C21/00

    摘要: An antimicrobial article having a substrate, and a coating on a surface of the substrate. The coating includes a silver-containing alkali silicate. The antimicrobial article has an antimicrobial efficacy of greater than or equal to about 90.0% according to EPA Test Method for Efficacy of Copper Alloy Surfaces as a Sanitizer. The coating may further include at least one of a boron-containing compound and an aluminum-containing compound. A method for forming antimicrobial articles includes coating a substrate with a mixture comprising an alkali silicate; curing the coating at a temperature from greater than or equal to about 300° C. to less than or equal to about 620° C. for a duration of greater than or equal to about 15 minutes to less than or equal to about 120 minutes; and contacting the coating with an antimicrobial medium comprising silver nitrate and an alkali nitrate.

    摘要翻译: 具有底物的抗微生物制品,以及在该基材的表面上的涂层。 涂层包括含银的碱性硅酸盐。 根据EPA“铜合金表面作为消毒剂的功效的测试方法”,抗微生物制品具有大于或等于约90.0%的抗菌功效。 该涂层还可包括含硼化合物和含铝化合物中的至少一种。 用于形成抗微生物制品的方法包括用包含碱性硅酸盐的混合物涂覆底物; 在大于或等于约300℃至小于或等于约620℃的温度下固化涂层,持续时间大于或等于约15分钟至小于或等于约120分钟; 并使涂层与包含硝酸银和硝酸碱金属的抗微生物培养基接触。

    Antimicrobial Composite Material
    10.
    发明申请
    Antimicrobial Composite Material 审中-公开
    抗菌复合材料

    公开(公告)号:US20140212467A1

    公开(公告)日:2014-07-31

    申请号:US14342615

    申请日:2012-09-07

    IPC分类号: A01N59/20 A01N25/34

    摘要: The present disclosure is directed to an antimicrobial composite material, and more particularly to an antimicrobial composite material comprising particles having a metal or metal alloy core and a porous inorganic material shell, coatings including the antimicrobial composite material, and methods of making the same. In some embodiments, Cu—SiO2 core-shell particles are disclosed in which the Cu core provides antimicrobial activity and the porous SiO2 shell functions as a barrier for the Cu core, thus preventing the Cu core from being directly exposed to air or moisture.

    摘要翻译: 本公开涉及抗微生物复合材料,更具体地涉及包含具有金属或金属合金芯和多孔无机材料壳的颗粒的抗微生物复合材料,包括抗微生物复合材料的涂层及其制备方法。 在一些实施方案中,公开了Cu-SiO2核 - 壳颗粒,其中Cu芯提供抗微生物活性,并且多孔SiO 2壳体用作Cu芯的屏障,从而防止Cu芯直接暴露于空气或水分。