公开(公告)号：US20240270941A1

公开(公告)日：2024-08-15

申请号：US18643241

申请日：2024-04-23

Applicant: CORNING INCORPORATED

Inventor： Andrew Charles Antony ,  Theresa Chang ,  Sushmit Sunil Kumar Goyal ,  Shrisudersan Jayaraman ,  Rui Qi ,  Vinalia Tjong ,  Shu Yuan

IPC: C08K13/02 ,  A01N25/08 ,  A01N59/20 ,  C08J5/18 ,  C08K3/40 ,  C08K5/00 ,  C08K5/315 ,  C08K5/521 ,  C08K5/524 ,  C08K5/5313 ,  C08K5/5333 ,  C09D5/14 ,  C09D7/20 ,  C09D7/48 ,  C09D7/61 ,  C09D7/63 ,  C09D125/06 ,  C09D133/12 ,  C09D179/08

CPC classification number: C08K13/02 ,  A01N25/08 ,  A01N59/20 ,  C08J5/18 ,  C09D5/14 ,  C09D7/20 ,  C09D7/48 ,  C09D7/61 ,  C09D7/63 ,  C09D125/06 ,  C09D133/12 ,  C09D179/08 ,  C08J2325/06 ,  C08J2333/12 ,  C08J2379/08 ,  C08K3/40 ,  C08K5/0091 ,  C08K5/315 ,  C08K5/521 ,  C08K5/524 ,  C08K5/5313 ,  C08K5/5333

Abstract: A method of forming an antimicrobial film, including providing a substrate with a polymer coating disposed thereon, the polymer coating including: an antimicrobial material, an inner surface contacting the substrate, and an outer surface opposite the inner surface; and extracting ions from the antimicrobial material toward the outer surface, such that the outer surface interacts with surface microorganisms. A composition, including a polymer; an antimicrobial material; and at least one of an organic solvent and an additive. The antimicrobial material comprises at least one of copper-containing glass particles, copper oxide particles, copper metal particles, copper salts, copper coordination complexes, cuprite crystals, and a combination thereof. Further, the additive can be selected to increase the oxidation resistance of the antimicrobial material.

公开(公告)号：US20240336885A1

公开(公告)日：2024-10-10

申请号：US18293676

申请日：2022-07-21

Applicant: CORNING INCORPORATED

Inventor： Yujian Sun ,  Vinalia Tjong ,  Yue Zhou

IPC: C12M1/12 ,  C12M1/00

CPC classification number: C12M25/18 ,  C12M25/02 ,  C12M29/10

Abstract: A bioreactor system for culturing cells is provided having a cell culture vessel with an interior reservoir, and an inlet and outlet connected to the reservoir. The system also includes a cell culture matrix in the reservoir for adhering cells thereto. The cell culture matrix maintains a uniform flow of liquid media through the cell culture matrix, such that the uniform flow satisfies the following expressions: wherein P is greater than or equal to at least one of 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, and 0.95, and wherein N is less than or equal to at least one of 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, and 1.0.

公开(公告)号：US20230357541A1

公开(公告)日：2023-11-09

申请号：US18218790

申请日：2023-07-06

Applicant: CORNING INCORPORATED

Inventor： Andrew Charles Antony ,  Theresa Chang ,  Sushmit Sunil Kumar Goyal ,  Shrisudersan Jayaraman ,  Rui Qi ,  Vinalia Tjong ,  Shu Yuan

IPC: C08K13/02 ,  C09D5/14 ,  C09D7/20 ,  C09D7/61 ,  C09D7/48 ,  C09D7/63 ,  C09D125/06 ,  C09D133/12 ,  C09D179/08 ,  C08J5/18 ,  A01N59/20 ,  A01N25/08

CPC classification number: C08K13/02 ,  C09D5/14 ,  C09D7/20 ,  C09D7/61 ,  C09D7/48 ,  C09D7/63 ,  C09D125/06 ,  C09D133/12 ,  C09D179/08 ,  C08J5/18 ,  A01N59/20 ,  A01N25/08 ,  C08K3/40

Abstract: A method of forming an antimicrobial film, including providing a substrate with a polymer coating disposed thereon, the polymer coating including: an antimicrobial material, an inner surface contacting the substrate, and an outer surface opposite the inner surface; and extracting ions from the antimicrobial material toward the outer surface, such that the outer surface interacts with surface microorganisms. A composition, including a polymer; an antimicrobial material; and at least one of an organic solvent and an additive. The antimicrobial material comprises at least one of copper-containing glass particles, copper oxide particles, copper metal particles, copper salts, copper coordination complexes, cuprite crystals, and a combination thereof. Further, the additive can be selected to increase the oxidation resistance of the antimicrobial material.

公开(公告)号：US11993692B2

公开(公告)日：2024-05-28

申请号：US18218790

申请日：2023-07-06

Applicant: CORNING INCORPORATED

Inventor： Andrew Charles Antony ,  Theresa Chang ,  Sushmit Sunil Kumar Goyal ,  Shrisudersan Jayaraman ,  Rui Qi ,  Vinalia Tjong ,  Shu Yuan

IPC: C08K13/02 ,  A01N25/08 ,  A01N59/20 ,  C08J5/18 ,  C08K3/40 ,  C08K5/00 ,  C08K5/315 ,  C08K5/521 ,  C08K5/524 ,  C08K5/5313 ,  C08K5/5333 ,  C09D5/14 ,  C09D7/20 ,  C09D7/48 ,  C09D7/61 ,  C09D7/63 ,  C09D125/06 ,  C09D133/12 ,  C09D179/08

CPC classification number: C08K13/02 ,  A01N25/08 ,  A01N59/20 ,  C08J5/18 ,  C09D5/14 ,  C09D7/20 ,  C09D7/48 ,  C09D7/61 ,  C09D7/63 ,  C09D125/06 ,  C09D133/12 ,  C09D179/08 ,  C08J2325/06 ,  C08J2333/12 ,  C08J2379/08 ,  C08K3/40 ,  C08K5/0091 ,  C08K5/315 ,  C08K5/521 ,  C08K5/524 ,  C08K5/5313 ,  C08K5/5333

Abstract: A method of forming an antimicrobial film, including providing a substrate with a polymer coating disposed thereon, the polymer coating including: an antimicrobial material, an inner surface contacting the substrate, and an outer surface opposite the inner surface; and extracting ions from the antimicrobial material toward the outer surface, such that the outer surface interacts with surface microorganisms. A composition, including a polymer; an antimicrobial material; and at least one of an organic solvent and an additive. The antimicrobial material comprises at least one of copper-containing glass particles, copper oxide particles, copper metal particles, copper salts, copper coordination complexes, cuprite crystals, and a combination thereof. Further, the additive can be selected to increase the oxidation resistance of the antimicrobial material.

公开(公告)号：US20230365907A1

公开(公告)日：2023-11-16

申请号：US18030665

申请日：2021-10-07

Applicant: CORNING INCORPORATED

Inventor： Theresa Chang ,  Paula Jean Dolley-Sonneville ,  Paul Ernest Gagnon, Jr. ,  Vinalia Tjong ,  Yue Zhou

IPC: C12M1/00 ,  C12M1/12

CPC classification number: C12M23/20 ,  C12M25/14

Abstract: A cell culture substrate is provided that includes a substrate lattice having an ordered array of fibers and pores disposed between the fibers. The ordered array of fibers includes a cell culture surface to support adherent or semi-adherent cells during cell culture. The cell culture substrate further includes a positive charge coating disposed on the cell culture surface to promote adhesion of cells to the cell culture surface.