公开(公告)号：US11104924B2

公开(公告)日：2021-08-31

申请号：US16473941

申请日：2017-10-20

Applicant: CJ Cheiljedang Corporation

Inventor： Ji Hye Lee ,  Byeong Cheol Song ,  Ae Ji Jeon ,  Jong Hyun Kim ,  Hye Won Kim

IPC: C12N9/00 ,  C12P13/06 ,  C12N9/10 ,  C12N15/52 ,  C12N15/77

Abstract: A novel modified polypeptide having an isopropylmalate synthase activity, a polynucleotide encoding the same, a microorganism comprising the polypeptide, and a method of producing L-leucine by culturing the microorganism.

公开(公告)号：US10457919B2

公开(公告)日：2019-10-29

申请号：US16195157

申请日：2018-11-19

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ae Ji Jeon ,  Byeong Cheol Song ,  Jong Hyun Kim ,  Hye Won Kim ,  Ji Hye Lee

IPC: C12P13/08 ,  C12N9/10 ,  C12N9/88 ,  C12R1/15

Abstract: The present disclosure relates to an acetohydroxy acid synthase variant in which the feedback inhibition to L-valine is released, a polynucleotide encoding the acetohydroxy acid synthase variant, an expression vector including the polynucleotide, a microorganism producing L-valine including the acetohydroxy acid synthase variant, and a method for producing L-valine using the microorganism.

公开(公告)号：US10316297B2

公开(公告)日：2019-06-11

申请号：US15501645

申请日：2015-08-05

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ae Ji Jeon ,  Byeong Cheol Song ,  Jong Hyun Kim ,  Hye Won Kim ,  Ji Hye Lee

IPC: C12P13/08 ,  C12N9/10 ,  C12N9/88 ,  C12R1/15

Abstract: The present disclosure relates to an acetohydroxy acid synthase variant in which the feedback inhibition to L-valine is released, a polynucleotide encoding the acetohydroxy acid synthase variant, an expression vector including the polynucleotide, a microorganism producing L-valine including the acetohydroxy acid synthase variant, and a method for producing L-valine using the microorganism.

公开(公告)号：US09885093B2

公开(公告)日：2018-02-06

申请号：US14898099

申请日：2013-06-11

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hye Won Kim ,  Ji Hye Lee ,  Jong Hyun Kim ,  Han Hyoung Lee ,  Ae Ji Jeon

IPC: C12P13/06 ,  C12N1/20 ,  C12R1/15 ,  C12P13/08 ,  C12N15/01

CPC classification number: C12R1/15 ,  C12N1/20 ,  C12P13/06 ,  C12P13/08

Abstract: The present invention relates to a microorganism having an enhanced ability to produce L-isoleucine and a method of producing L-isoleucine using the same. More specifically, the present invention relates to a Corynebacterium glutamicum mutant strain, which is resistant to L-isoleucine and L-threonine derivatives and has an enhanced ability to produce L-isoleucine, and to a method of producing L-isoleucine using the mutant strain.

公开(公告)号：US11085029B2

公开(公告)日：2021-08-10

申请号：US17076057

申请日：2020-10-21

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ae Ji Jeon ,  Byeong Cheol Song ,  Ji Hye Lee ,  Jong Hyun Kim ,  Hye Won Kim

IPC: C12N9/10 ,  C12P13/06 ,  C12P13/08

Abstract: The present disclosure relates to a novel acetohydroxy acid synthase, a microorganism comprising the same, or a method for producing an L-branched-chain amino acid using the same.

公开(公告)号：US20190233859A1

公开(公告)日：2019-08-01

申请号：US15758248

申请日：2016-09-09

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Sol Kim ,  Min Gyeong Kang ,  In Hwa Yoo ,  Jong Hyun Kim ,  Hye Won Kim

IPC: C12P13/12 ,  C07K14/245 ,  C12N9/10 ,  C12N9/16 ,  C12N15/70

CPC classification number: C12P13/12 ,  C07K14/245 ,  C12N9/10 ,  C12N9/16 ,  C12N15/70

Abstract: The present disclosure relates to a novel polypeptide having O-phosphoserine (OPS) exporting activity, a polynucleotide encoding the polypeptide, a microorganism expressing the polypeptide, a method for producing OPS using the microorganism, and a method for producing cysteine or a derivative thereof comprising reacting the O-phosphoserine produced by the same with a sulfide, in the presence of O-phosphoserine sulfhydrylase (OPSS) or a microorganism expressing the same.

公开(公告)号：US11905539B2

公开(公告)日：2024-02-20

申请号：US17156998

申请日：2021-01-25

Applicant: CJ Cheiljedang Corporation

Inventor： Ji Hye Lee ,  Byeong Cheol Song ,  Ae Ji Jeon ,  Jong Hyun Kim ,  Hye Won Kim

IPC: C12P13/06 ,  C12N9/10 ,  C12N15/52 ,  C12N15/77 ,  C12N15/74

CPC classification number: C12P13/06 ,  C12N9/1025 ,  C12N15/52 ,  C12N15/74 ,  C12N15/77 ,  C12Y203/03013

Abstract: A novel modified polypeptide having an isopropylmalate synthase activity, a polynucleotide encoding the same, a microorganism including the polypeptide, and a method of producing L-leucine by culturing the microorganism.

公开(公告)号：US11345901B2

公开(公告)日：2022-05-31

申请号：US17357196

申请日：2021-06-24

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ae Ji Jeon ,  Byeong Cheol Song ,  Ji Hye Lee ,  Jong Hyun Kim ,  Hye Won Kim

IPC: C12N9/10 ,  C12P13/06 ,  C12P13/08

Abstract: The present disclosure relates to a novel acetohydroxy acid synthase, a microorganism comprising the same, or a method for producing an L-branched-chain amino acid using the same.

公开(公告)号：US11248220B2

公开(公告)日：2022-02-15

申请号：US17225756

申请日：2021-04-08

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ae Ji Jeon ,  Byeong Cheol Song ,  Ji Hye Lee ,  Jong Hyun Kim ,  Hye Won Kim

IPC: C12N9/88 ,  C12P13/06 ,  C12P13/08 ,  C12N15/77 ,  C12N9/10

Abstract: The present disclosure relates to a novel acetohydroxy acid synthase, a microorganism comprising the same, or a method for producing an L-branched-chain amino acid using the same.

公开(公告)号：US10351859B2

公开(公告)日：2019-07-16

申请号：US15754903

申请日：2016-08-25

Applicant: CJ Cheiljedang Corporation

Inventor： Byeong Cheol Song ,  Ji Hye Lee ,  Ae Ji Jeon ,  Jong Hyun Kim ,  Hye Won Kim

IPC: C12P13/06 ,  C12N15/77 ,  C12R1/15

Abstract: The present disclosure relates to a microorganism producing L-leucine and a method for producing L-leucine using the same, and more specifically, to a Corynebacterium glutamicum mutant which has resistance to L-leucine and a derivative thereof and improved L-leucine producing ability, and a method for producing L-leucine using the same.