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公开(公告)号：US11858879B2
公开(公告)日：2024-01-02
申请号：US16625511
申请日：2018-06-22
Applicant: City of Hope
Inventor： Xiaochun Yu , Shih-Hsun Chen , Yate-Ching Yuan , Hongzhi Li , David Horne
IPC: C07C251/86 , C07C311/17 , C07C311/29 , A61P35/00
CPC classification number: C07C251/86 , A61P35/00 , C07C311/17 , C07C311/29
Abstract: Provided herein are, inter alia, compounds inhibiting poly(ADP-ribose) Glycohydrolase (PARG) in a cancer cell and methods of treating cancer using compounds of the invention.
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公开(公告)号：US20200148645A1
公开(公告)日：2020-05-14
申请号：US16741559
申请日：2020-01-13
Applicant: City of Hope , California Institute of Technology
Inventor： Binghui Shen , Judith Campbell , Li Zheng , Hongzhi Li , David Horne , Jun Xie , Kenneth Karanja
IPC: C07D215/56 , A61K45/06 , A61K31/47
Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.
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公开(公告)号：US20180134664A1
公开(公告)日：2018-05-17
申请号：US15866268
申请日：2018-01-09
Applicant: City of Hope , California Institute of Technology
Inventor： Binghui Shen , Judith Campbell , Li Zheng , Hongzhi Li , David Horne , Jun Xie , Kenneth Karanja
IPC: C07D215/56 , A61K31/47 , A61K45/06
CPC classification number: C07D215/56 , A61K31/47 , A61K45/06
Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.
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公开(公告)号：US09932310B2
公开(公告)日：2018-04-03
申请号：US15428021
申请日：2017-02-08
Applicant: City of Hope , California Institute of Technology
Inventor： Binghui Shen , Judith Campbell , Li Zheng , Hongzhi Li , David Horne , Jun Xie , Kenneth Karanja
IPC: C07D215/00 , C07D215/56 , A61K45/06 , A61K31/47
CPC classification number: C07D215/56 , A61K31/47 , A61K45/06
Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.
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公开(公告)号：US11780815B2
公开(公告)日：2023-10-10
申请号：US17515252
申请日：2021-10-29
Applicant: City of Hope , California Institute of Technology
Inventor： Binghui Shen , Judith Campbell , Li Zheng , Hongzhi Li , David Horne , Jun Xie , Kenneth Karanja
IPC: C07D215/56 , A61K31/47 , A61K45/06
CPC classification number: C07D215/56 , A61K31/47 , A61K45/06
Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.
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Patent Agency Ranking
公开(公告)号：US20230127630A1
公开(公告)日：2023-04-27
申请号：US17794922
申请日：2021-01-27
Applicant: CITY OF HOPE
Inventor： Jianjun Chen , Hengyou Weng , Huilin Huang , David Horne , Yuelong Ma , Hongzhi Li , Xiaolan Deng
IPC: C07C243/38
Abstract: Described herein, inter alia, are IGF2BP2 inhibitor compounds and methods of using the same.
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公开(公告)号：US20220339155A1
公开(公告)日：2022-10-27
申请号：US17632963
申请日：2020-08-20
Applicant: City of Hope
Inventor： Jianjun Chen , Xiaolan Deng , Li Han , Hongzhi Li , Rui Su
IPC: A61K31/519
Abstract: The disclosure provides, inter alia, METTL16 inhibitors and methods of treating cancers that overexpress METTL16.
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公开(公告)号：US20230190717A1
公开(公告)日：2023-06-22
申请号：US16604151
申请日：2018-04-09
Applicant: City of Hope
Inventor： Xu Hannah Zhang , Steve Rosen , David Horne , Sangkil Nam , Hongzhi Li , Jun Xie
IPC: A61K31/437 , A61K45/06 , A61P35/00 , A61P7/00 , C07D471/04 , A61K31/167
CPC classification number: A61K31/437 , A61K45/06 , A61P35/00 , A61P7/00 , C07D471/04 , A61K31/167
Abstract: Provided herein, inter alia, are methods of treating cancer or cutaneous T-cell lymphoma (CTCL) using compounds of the invention.
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公开(公告)号：US20190092732A1
公开(公告)日：2019-03-28
申请号：US16206611
申请日：2018-11-30
Applicant: City of Hope , California Institute of Technology
Inventor： Binghui Shen , Judith Campbell , Li Zheng , Hongzhi Li , David Horne , Jun Xie , Kenneth Karanja
IPC: C07D215/56 , A61K45/06 , A61K31/47
CPC classification number: C07D215/56 , A61K31/47 , A61K45/06
Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.
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公开(公告)号：US20170226063A1
公开(公告)日：2017-08-10
申请号：US15428021
申请日：2017-02-08
Applicant: City of Hope , California Institute of Technology
Inventor： Binghui Shen , Judith Campbell , Li Zheng , Hongzhi Li , David Horne , Jun Xie , Kenneth Karanja
IPC: C07D215/56 , A61K31/47 , A61K45/06
CPC classification number: C07D215/56 , A61K31/47 , A61K45/06
Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.
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