公开(公告)号：US20160072472A1

公开(公告)日：2016-03-10

申请号：US14627801

申请日：2015-02-20

申请人： CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation

发明人： Gary K. Fedder ,  Congzhong Guo

IPC分类号： H03H9/02

CPC分类号： H03J1/00 ,  G01C19/5776 ,  G01L1/10 ,  G01N29/022 ,  G01N29/036 ,  G01N29/12 ,  G01N2291/02491 ,  G01N2291/0256

摘要： A bi-state bifurcation-based control system and method for nonlinear resonators, which utilizes a control loop to servo on the edge of the bifurcation jump, either at the maximum “on” point prior to the Duffing bifurcation jump or along the rising edge of the parametric bifurcation.

摘要翻译： 一种用于非线性谐振器的双态分岔控制系统和方法，其利用控制回路在分岔跳跃的边缘上进行伺服，或者在Duffing分岔跳跃之前的最大“开”点处，或沿着上升沿 参数分岔。

公开(公告)号：US10292656B2

公开(公告)日：2019-05-21

申请号：US14962016

申请日：2015-12-08

申请人： CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation

发明人： Gary K. Fedder ,  Burak Ozdoganlar ,  Peter J. Gilgunn

IPC分类号： A01B5/00 ,  H01L21/50 ,  A61B5/00 ,  A61B5/0478 ,  A61N1/05 ,  B29C41/04 ,  B29C35/02 ,  B29C35/08 ,  B29C41/20 ,  B29C41/42 ,  G03F7/00 ,  B29K1/00 ,  B29L31/00

摘要： Methods of fabricating ultra-miniature, ultra-compliant probe arrays through spin coating, wherein a dissolvable material in hydrogel form is dispensed onto an assembled mold with wires. Once the dissolvable material is dispensed onto the mold, centrifuging spin casts the material by evaporating the solvent, forming a dried dissolvable polymer. Finally, a device is used with water to remove excess dissolvable material to obtain a dissolvable needle with wires.

公开(公告)号：US10608614B2

公开(公告)日：2020-03-31

申请号：US14627801

申请日：2015-02-20

申请人： CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation

发明人： Gary K. Fedder ,  Congzhong Guo

IPC分类号： H01L23/473 ,  H02M1/14 ,  H02M1/34 ,  H03J1/00 ,  G01N29/12 ,  G01N29/036 ,  G01L1/10 ,  G01N29/02 ,  G01C19/5776

摘要： A bi-state bifurcation-based control system and method for nonlinear resonators, which utilizes a control loop to servo on the edge of the bifurcation jump, either at the maximum “on” point prior to the Duffing bifurcation jump or along the rising edge of the parametric bifurcation.

公开(公告)号：US20160128636A1

公开(公告)日：2016-05-12

申请号：US14962016

申请日：2015-12-08

申请人： CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation

发明人： Gary K. Fedder ,  Burak Ozdoganlar ,  Peter J. Gilgunn

IPC分类号： A61B5/00 ,  B29C41/04 ,  G03F7/00 ,  B29C41/42 ,  B29C35/08 ,  B29C35/02 ,  A61B5/0478 ,  B29C41/20

CPC分类号： A61B5/6848 ,  A61B5/0478 ,  A61B5/685 ,  A61B2562/028 ,  A61B2562/046 ,  A61B2562/125 ,  A61B2562/222 ,  A61N1/0534 ,  B29C35/02 ,  B29C35/0805 ,  B29C41/04 ,  B29C41/20 ,  B29C41/42 ,  B29C2035/0827 ,  B29K2001/08 ,  B29K2907/00 ,  B29K2995/006 ,  B29L2031/753 ,  G03F7/0035 ,  Y10T29/49826

摘要： Methods, systems and apparatuses of ultra-miniature, ultra-compliant probe arrays that allows for design flexibility to match the stiffness of the tissue it is being applied to, such as the brain tissue, in all three axes (x, y and z), with interconnect cross section smaller than cell dimensions. Stiffness matching requires specific geometric and fabrication approaches, commonly leading to ultra-thin probe wires. Sizing of the electrodes for specific cell dimensions reduces glial formation. Further reduction in stiffness is obtained by incorporating different geometric features to the electrode, such as meandering the electrode wires. The small thickness and geometric features of the wires commonly result in very high compliance. To enable effective insertion of the probes to the tissue, the present invention uses stiff biodisolvable and/or biodegradable polymers, including single use or combinations of carboxymethyl cellulose, polyvinylpyrrolidone, polyvinyl alcohol, maltose, other sugar molecules, polylactic acid and its co-polymers.