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公开(公告)号：US20130012800A1
公开(公告)日：2013-01-10
申请号：US13613419
申请日：2012-09-13
申请人： Brian P. Brockway , Perry A. Mills
发明人： Brian P. Brockway , Perry A. Mills
IPC分类号： A61B5/042
CPC分类号： A61B5/686 , A61B5/0031 , A61B5/042 , A61B5/0422 , A61B5/076 , A61B5/7232 , A61B2560/0219 , A61B2560/063 , A61B2560/066 , A61B2562/0209 , A61B2562/164 , A61B2562/18 , A61N1/0504 , A61N1/37229 , A61N1/375 , A61N1/3756 , A61N1/3787
摘要： An implantable monitoring device includes a flexible lead body that includes at least one sensing element. The device also includes a rigid main body connected to the flexible lead body at an attachment point. The rigid main body is generally centered about a longitudinal axis defined by the flexible lead body when the lead body is unflexed. The device further includes a measurement circuit, which is housed within the rigid main body and electrically coupled to the at least one sensing element of the flexible lead body and at least another sensing element on an outside surface of the rigid main body. The measurement circuit is configured to measure a potential difference between the at least one sensing element of the flexible lead body and the at least another sensing element of the main body.
摘要翻译： 可植入监测装置包括一个包括至少一个传感元件的柔性引线体。 该装置还包括在附接点处连接到柔性引线主体的刚性主体。 当铅体未折叠时，刚性主体通常由柔性引线体限定的纵向轴线对准。 该装置还包括测量电路，该测量电路容纳在刚性主体内并且电耦合到柔性引线本体的至少一个感测元件以及刚性主体的外表面上的至少另一个感测元件。 测量电路被配置为测量柔性引线体的至少一个感测元件与主体的至少另一感测元件之间的电位差。
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公开(公告)号：US4562841A
公开(公告)日：1986-01-07
申请号：US405711
申请日：1982-08-05
申请人： Brian P. Brockway , Robert D. Dreher , Daniel E. Huntwork , Brock S. Lindstedt , Douglas C. Morrison , Perry A. Mills
发明人： Brian P. Brockway , Robert D. Dreher , Daniel E. Huntwork , Brock S. Lindstedt , Douglas C. Morrison , Perry A. Mills
CPC分类号： A61N1/37252 , A61N1/3622 , A61N1/368 , A61N1/3688 , A61N1/37223
摘要： A programmable cardiac pacemaker that is selectively programmable via a radio frequency communications link into one of a plurality of a single and dual chamber pacing modes. Depending upon the mode selected, an associated plurality of pacing parameters may be programmed, each within a predetermined range of possible magnitudes.The pacemaker includes a rate smoothing function for preventing the rate interval from changing by more than a predetermined percentage on a cycle-to-cycle basis; and a graceful degradation function for causing the ventricular pacing rate to decay when the atrial rate exceeds a programmed upper rate limit for a predetermined length of time. A graceful degration onset time and rate of decay are also programmable. Additionally, the pacemaker contains a set of pre-programmed alternative pacing parameters for at least one mode and which can be independently reverted to.The pacemaker control circuitry is organized about a central bus into an I/O controller and a pacing controller. Pacing control is continuous and its I/O communications operate on a prioritized basis. I/O control permits the programming of any register and the interrogation of a variety of analog parameters associated therewith.
摘要翻译： 一种可编程的心脏起搏器，其可经由射频通信链路选择性地编程为多个单室起搏模式和双室起搏模式之一。 根据所选择的模式，相关联的多个起搏参数可以被编程，每个在可能的幅度的预定范围内。 起搏器包括速率平滑功能，用于在循环到循环的基础上防止速率间隔改变超过预定百分比; 以及当心房速率超过编程的上限速度达预定时间长度时，使心室起搏速率衰减的优雅降解功能。 优雅的降级开始时间和衰减速率也是可编程的。 此外，起搏器包含一组用于至少一种模式的预先编程的替代起搏参数，并且可以独立地还原。 将起搏器控制电路组织为一个中央总线到I / O控制器和起搏控制器中。 起搏控制是连续的，其I / O通信以优先级为基础进行操作。 I / O控制允许编程任何寄存器和询问与之相关的各种模拟参数。
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公开(公告)号：US20090118597A1
公开(公告)日：2009-05-07
申请号：US12265541
申请日：2008-11-05
IPC分类号： A61B5/04
CPC分类号： A61B5/0031 , A61B5/4035 , A61B2560/0209
摘要： A method of monitoring neural signal activity with an implantable monitoring device implanted in a living subject includes amplifying a neural signal having a signal bandwidth of at least 1000 Hz. The method also includes processing the amplified neural signal to produce a reduced-bandwidth derivative neural signal representative of gross activity of the neural signal, and wirelessly transmitting the derivative neural signal from the implantable monitoring device for receipt by a receiver external of the living subject.
摘要翻译： 使用植入生物体内的可植入监测装置监测神经信号活动的方法包括放大具有至少1000Hz的信号带宽的神经信号。 该方法还包括处理放大的神经信号以产生代表神经信号的总活动的减少带宽的导数神经信号，以及无线地从可植入监测装置传输导数神经信号，以便由生物体的外部的接收器接收。
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公开(公告)号：US06962580B2
公开(公告)日：2005-11-08
申请号：US10246324
申请日：2002-09-17
CPC分类号： A61M39/0208 , A61M5/158 , A61M5/16831 , A61M2039/0226 , A61M2039/0244
摘要： A vascular access port system including circuits for detecting and indicating the presence or absence of a needle. The detecting and indicating circuits may be carried in whole or in part by one of or both of the needle and/or the vascular access port. The detecting and indicating circuits may utilize a conductive needle, a mechanical switch, a magnetic switch, a Hall effect sensor, an electric field, a magnetic field, or an inductor, for example, for detection purposes. The vascular access port system permits the practitioner to confirm that the needle has been correctly inserted into the VAP, and notifies the patient and/or practitioner if the needle has been accidentally withdrawn.
摘要翻译： 一种血管通路系统，包括用于检测和指示针的存在或不存在的电路。 检测和指示电路可以全部或部分地由针和/或血管进入口中的一个或两者承载。 检测和指示电路可以使用导电针，机械开关，磁性开关，霍尔效应传感器，电场，磁场或电感器，例如用于检测目的。 血管通路系统允许从业者确认针已被正确地插入到VAP中，并且如果针被意外地取出，则通知患者和/或从业者。
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公开(公告)号：US20090192381A1
公开(公告)日：2009-07-30
申请号：US12362812
申请日：2009-01-30
申请人： Brian P. Brockway , Perry A. Mills
发明人： Brian P. Brockway , Perry A. Mills
IPC分类号： A61B5/04
CPC分类号： A61B5/686 , A61B5/0031 , A61B5/042 , A61B5/0422 , A61B5/076 , A61B5/7232 , A61B2560/0219 , A61B2560/063 , A61B2560/066 , A61B2562/0209 , A61B2562/164 , A61B2562/18 , A61N1/0504 , A61N1/37229 , A61N1/375 , A61N1/3756 , A61N1/3787
摘要： An implantable monitoring device includes a flexible lead body that includes at least one sensing element. The device also includes a rigid main body connected to the flexible lead body at an attachment point. The rigid main body is generally centered about a longitudinal axis defined by the flexible lead body when the lead body is unflexed. The device further includes a measurement circuit, which is housed within the rigid main body and electrically coupled to the at least one sensing element of the flexible lead body and at least another sensing element on an outside surface of the rigid main body. The measurement circuit is configured to measure a potential difference between the at least one sensing element of the flexible lead body and the at least another sensing element of the main body.
摘要翻译： 可植入监测装置包括一个包括至少一个传感元件的柔性引线体。 该装置还包括在附接点处连接到柔性引线主体的刚性主体。 当铅体未折叠时，刚性主体通常由柔性引线体限定的纵向轴线对准。 该装置还包括测量电路，该测量电路容纳在刚性主体内并且电耦合到柔性引线本体的至少一个感测元件以及刚性主体的外表面上的至少另一个感测元件。 测量电路被配置为测量柔性引线体的至少一个感测元件与主体的至少另一感测元件之间的电位差。
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公开(公告)号：US07347843B2
公开(公告)日：2008-03-25
申请号：US11190789
申请日：2005-07-26
IPC分类号： A61M31/00
CPC分类号： A61M39/0208 , A61M5/158 , A61M5/16831 , A61M2039/0226 , A61M2039/0244
摘要： A vascular access port system including means for detecting and indicating the presence or absence of a needle. The detecting and indicating means may be carried in whole or in part by one of or both of the needle and/or the vascular access port. The detecting and indicating means may utilize a conductive needle, a mechanical switch, a magnetic switch, a Hall effect sensor, an electric field, a magnetic field, or an inductor, for example, for detection purposes. The vascular access port system permits the practitioner to confirm that the needle has been correctly inserted into the VAP, and notifies the patient and/or practitioner if the needle has been accidentally withdrawn.
摘要翻译： 一种血管通路系统，包括用于检测和指示针的存在或不存在的装置。 检测和指示装置可以全部或部分地由针和/或血管进入口中的一个或两个承载。 检测和指示装置可以使用导电针，机械开关，磁开关，霍尔效应传感器，电场，磁场或电感器，例如用于检测目的。 血管通路系统允许从业者确认针已被正确地插入到VAP中，并且如果针被意外地取出，则通知患者和/或从业者。
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公开(公告)号：US06296615B1
公开(公告)日：2001-10-02
申请号：US09264147
申请日：1999-03-05
IPC分类号： A61B502
摘要： The disclosed embodiments present improved catheters with physiological sensors. In one embodiment, the catheter includes, generally, a pressure transducer/electronics assembly connected to a pressure transmission catheter. The pressure transmission catheter includes a hollow tube made from a low compliance material. The distal end of the hollow tube is filled with a gel-like material or plug which acts as a barrier between the catheter liquid and the target fluid. The hollow tube is partially filled with a low viscosity liquid and is in fluid communication with the gel-like material and the pressure transducer. The pressure of the target fluid is transmitted to the liquid in the hollow tube through the gel-like material and/or the wall of the distal tip and is fluidically transmitted to the pressure transducer. The pressure transmission catheter is capable of being inserted into a vessel lumen or inserted into a lumen of a therapeutic or diagnostic catheter for biomedical applications. This provides the ability to directly measure the pressure effects of the treatment catheter. In another embodiment, the distal end of the pressure transmission catheter may be electrically conductive so as to detect and transmit an electric signal. Thus, in this embodiment, the catheter can be used to detect a physiological signal.
摘要翻译： 所公开的实施例使用生理传感器呈现改进的导管。 在一个实施例中，导管通常包括连接到压力传递导管的压力传感器/电子组件。 压力传递导管包括由低顺应性材料制成的中空管。 中空管的远端填充有凝胶状材料或塞子，其作为导管液体和目标流体之间的屏障。 中空管部分地填充有低粘度液体并与凝胶状材料和压力传感器流体连通。 目标流体的压力通过凝胶状材料和/或远侧末端的壁传递到中空管中的液体，并且被流体传递到压力传感器。 压力传递导管能够插入血管内腔或插入用于生物医学应用的治疗或诊断导管的内腔中。 这提供了直接测量治疗导管的压力作用的能力。 在另一个实施例中，压力传输导管的远端可以是导电的，以便检测和传输电信号。 因此，在本实施例中，导管可用于检测生理信号。
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8.发明授权
公开(公告)号：US4796641A
公开(公告)日：1989-01-10
申请号：US69728
申请日：1987-07-06
申请人： Perry A. Mills , Brian P. Brockway
发明人： Perry A. Mills , Brian P. Brockway
IPC分类号： A61B5/0215 , A61B5/07 , A61B5/00
CPC分类号： A61B5/076 , A61B5/0215 , Y10S128/13 , Y10S128/903
摘要： A device capable of sensing pressure allows the sensor and amplifying electronics to be packaged in a very small size and implanted within the body. The sensor consists of a small catheter, the tip of which is placed at the point at which pressure is to be measured, attached to a solid-state pressure sensor. The catheter is filled with a fluid and is connected to an implantable infusion pump which dispenses through the lumen of the catheter, heparin or other drug which inhibits thrombogenisis.
摘要翻译： 能够感测压力的装置允许将传感器和放大电子装置以非常小的尺寸包装并植入体内。 传感器由一个小导管组成，其小尖端被放置在要测量的压力点上，连接到固态压力传感器。 导管填充有流体并且连接到可植入输液泵，其通过导管的内腔，肝素或其它抑制血栓形成的药物而分配。
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公开(公告)号：US08996124B2
公开(公告)日：2015-03-31
申请号：US12198681
申请日：2008-08-26
申请人： Reid Bornhoft , Brian P. Brockway , Matt Kunz , Gregg Lichtscheidl , Brock Lindstedt , Perry A. Mills
发明人： Reid Bornhoft , Brian P. Brockway , Matt Kunz , Gregg Lichtscheidl , Brock Lindstedt , Perry A. Mills
IPC分类号： H03K9/04 , H04L25/493 , G08C19/24 , H04B14/02 , H04L25/49
CPC分类号： H04L25/493 , A61B5/07 , G08C19/24 , H04B14/026 , H04L25/4902
摘要： A system and method involve transceiving successive first and second synchronization signals defining endpoints of a frame. A digital signal is transceived by a modulating time interval between portions of the first and second synchronization signals. A first data pulse is transceived during the frame. A relative position in the frame of the first data pulse represents a first analog signal.
摘要翻译： 系统和方法涉及收发定义帧的端点的连续的第一和第二同步信号。 数字信号通过第一和第二同步信号的部分之间的调制时间间隔收发。 在帧期间收发第一个数据脉冲。 第一数据脉冲的帧中的相对位置表示第一模拟信号。
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10.发明授权Method for implanting a minimally invasive physiologic parameter recorder and introducer system 有权植入微创生理参数记录仪和导引器系统的方法公开(公告)号：US08280499B2
公开(公告)日：2012-10-02
申请号：US13465314
申请日：2012-05-07
申请人： Brian P. Brockway , Perry A. Mills
发明人： Brian P. Brockway , Perry A. Mills
CPC分类号： A61B5/686 , A61B5/0031 , A61B5/042 , A61B5/0422 , A61B5/076 , A61B5/7232 , A61B2560/0219 , A61B2560/063 , A61B2560/066 , A61B2562/0209 , A61B2562/164 , A61B2562/18 , A61N1/0504 , A61N1/37229 , A61N1/375 , A61N1/3756 , A61N1/3787
摘要： An implantable monitoring device includes a flexible lead body that includes at least one sensing element. The device also includes a rigid main body connected to the flexible lead body at an attachment point. The rigid main body is generally centered about a longitudinal axis defined by the flexible lead body when the lead body is unflexed. The device further includes a measurement circuit, which is housed within the rigid main body and electrically coupled to the at least one sensing element of the flexible lead body and at least another sensing element on an outside surface of the rigid main body. The measurement circuit is configured to measure a potential difference between the at least one sensing element of the flexible lead body and the at least another sensing element of the main body.
摘要翻译： 可植入监测装置包括一个包括至少一个传感元件的柔性引线体。 该装置还包括在附接点处连接到柔性引线主体的刚性主体。 当铅体未折叠时，刚性主体通常由柔性引线体限定的纵向轴线对准。 该装置还包括测量电路，该测量电路容纳在刚性主体内并且电耦合到柔性引线本体的至少一个感测元件以及刚性主体的外表面上的至少另一个感测元件。 测量电路被配置为测量柔性引线体的至少一个感测元件与主体的至少另一感测元件之间的电位差。
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