公开(公告)号：US20210213039A1

公开(公告)日：2021-07-15

申请号：US17218814

申请日：2021-03-31

Applicant: Bitop AG

Inventor： Andreas Bilstein ,  Olaf Scherner ,  Georg Lentzen

IPC: A61K31/7032 ,  A61L26/00 ,  A61K31/505 ,  A61K45/06 ,  C07D239/06 ,  C07H15/04

Abstract: The invention relates to a composition containing as active agent ectoine, hydroxyectoine, glucosylglycerol and/or salts, esters or amides of these compounds for promoting the regeneration of injured body tissue. The invention has special significance for the treatment of chronic wounds or ulcers.

公开(公告)号：US20180353505A1

公开(公告)日：2018-12-13

申请号：US15780964

申请日：2016-12-02

Applicant: bitop AG

Inventor： Andreas Bilstein ,  Olaf Scherner

IPC: A61K31/505 ,  A61K8/49 ,  A61Q17/00 ,  A61P37/08 ,  A61P39/00 ,  A61Q19/00

CPC classification number: A61K31/505 ,  A61K8/4953 ,  A61P37/08 ,  A61P39/00 ,  A61Q11/00 ,  A61Q17/00 ,  A61Q19/007

Abstract: The invention relates to a compatible solute or a solute mixture as well as to a composition comprising at least one solute or one solute mixture for use in the prevention or treatment of barrier malfunctions of epithelial tissues associated with at least one biobased noxa, in particular of diseases comprising at least one barrier malfunction in at least one cell layer of at least one epithelial tissue, wherein at least one solute is selected from compounds of formula I, of formula II, physiologically compatible salts of formula I, formula II, stereoisomeric forms of the compounds of formula I, formula II, and physiologically compatible salts of the stereoisomeric forms, or a mixture of at least two of the afore-mentioned compounds. The at least one compatible solute, solute mixture and/or the compositions are provided in the form of a cosmetic, medical product, medicament, of an additive to one of the afore-mentioned products or as component of an in-vitro diagnostic product (IVD).

公开(公告)号：US20170189435A1

公开(公告)日：2017-07-06

申请号：US15469055

申请日：2017-03-24

Applicant: bitop AG

Inventor： Andreas Bilstein ,  Olaf Scherner ,  Georg Lentzen

IPC: A61K31/7032 ,  A61K45/06 ,  A61K31/505

Abstract: The invention relates to a composition containing as active agent ectoine, hydroxyectoine, glucosylglycerol and/or salts, esters or amides of these compounds for promoting the regeneration of injured body tissue. The invention has special significance for the treatment of chronic wounds or ulcers.