公开(公告)号：US10973934B2

公开(公告)日：2021-04-13

申请号：US16766619

申请日：2019-08-06

Applicant: BRACCO IMAGING S.P.A.

Inventor： Roberta Napolitano ,  Luciano Lattuada ,  Zsolt Baranyai ,  Nicole Guidolin ,  Giuseppe Marazzi

IPC: A61B5/055 ,  A61K49/10 ,  C07F5/00

Abstract: The present invention relates to the RRR/SSS pair of enantiomers of the of Gd(PCTA-tris-glutaric acid), the single enantiomers of the pair, the pharmaceutically acceptable salts thereof, their amide derivatives, and compositions comprising at least 50% of these compounds.

公开(公告)号：US12036289B2

公开(公告)日：2024-07-16

申请号：US17199122

申请日：2021-03-11

Applicant: BRACCO IMAGING S.P.A.

Inventor： Roberta Napolitano ,  Luciano Lattuada ,  Zsolt Baranyai ,  Nicole Guidolin ,  Giuseppe Marazzi

IPC: A61B5/055 ,  A61K49/10 ,  C07F5/00 ,  C07D471/08

CPC classification number: A61K49/106 ,  C07F5/003 ,  A61K49/108 ,  C07D471/08

Abstract: The present invention relates to the RRR/SSS pair of enantiomers of the of Gd(PCTA-tris-glutaric acid), the single enantiomers of the pair, the pharmaceutically acceptable salts thereof, their amide derivatives, and compositions comprising at least 50% of these compounds.