公开(公告)号：US20160327578A1

公开(公告)日：2016-11-10

申请号：US14706834

申请日：2015-05-07

Applicant: Boston Heart Diagnostics Corporation

Inventor： Bela F. Asztalos ,  Michael Riel-Mehan ,  Ernst J. Schaefer

IPC: G01N33/92

CPC classification number: G01N33/92 ,  G01N2405/00 ,  G01N2500/04 ,  G01N2800/32 ,  G01N2800/50 ,  G01N2800/52 ,  G16B20/00 ,  G16H50/20 ,  G16H50/30

Abstract: A method is provided for transforming one or more biomarkers into a cholesterol efflux capacity (CEC) level. Methods relate to determining SR-BI-mediated and ABCA1-mediated CEC. CEC may be used for compound screening and to determine risk of cardiovascular disease and to recommend or administer treatment regimens.

Abstract translation: 提供了将一种或多种生物标志物转化为胆固醇流出能力（CEC）水平的方法。 方法涉及确定SR-BI介导的和ABCA1介导的CEC。 CEC可用于化合物筛选和确定心血管疾病的风险，并推荐或施用治疗方案。

公开(公告)号：US20180211722A1

公开(公告)日：2018-07-26

申请号：US15877726

申请日：2018-01-23

Applicant: BOSTON HEART DIAGNOSTICS CORPORATION

Inventor： Michael Dansinger ,  Michael Riel-Mehan ,  Julia Maddalena

IPC: G16H20/17 ,  G06F19/26 ,  G16H50/50

CPC classification number: G16H20/17 ,  G16B45/00 ,  G16H20/10 ,  G16H50/30 ,  G16H50/50

Abstract: An insulin activity map is a tool for assessing a patient's metabolic risk, designing a treatment plan, disseminating the information in a useful way to the patient, and encouraging the patient to remain on a treatment course. The insulin activity map combines a variety of inputs such as insulin sensitivity and insulin production to generate a patient-specific diagnosis and treatment assessment. The insulin activity map fills an important gap in prior art testing methods, providing diagnostic insights that improve clinician and patient understanding of the progression of diabetes, allows at-risk patients to more easily avoid developing diabetes, and helps diabetic and prediabetic patients manage and control the disease.