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公开(公告)号：US12280371B2
公开(公告)日：2025-04-22
申请号：US17609816
申请日：2021-01-15
Inventor： Haochen Cui , Jing Li , Tao Hu , Lijiao Hu , Chungen Yuan , Xiaohe Shen
IPC: B01L3/00
Abstract: A detection chip and a detection system are provided. The detection chip includes a base substrate, a flow channel defining layer, and at least one driving electrode group. The at least one driving electrode group is on the base substrate, and the flow channel defining layer is on a side of the at least one driving electrode group away from the base substrate, the flow channel defining layer includes a flow channel structure, and the flow channel structure is configured to accommodate liquid; and each of the at least one driving electrode group includes a plurality of driving electrodes, and the plurality of driving electrodes are configured to contact the liquid and drive the liquid to move within the flow channel structure.
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公开(公告)号：US11103868B2
公开(公告)日：2021-08-31
申请号：US16338042
申请日：2018-10-11
Inventor： Fengchun Pang , Peizhi Cai , Yue Geng , Le Gu , Yingying Zhao , Haochen Cui , Nan Zhao , Yuelei Xiao , Hui Liao , Chuncheng Che
IPC: B01L3/00
Abstract: The present disclosure provides a microfluidic chip, a biological detection device and a method. The microfluidic chip includes: a first substrate and a second substrate that are oppositely disposed; a first electrode and a second electrode that are oppositely disposed between the first substrate and the second substrate, the first electrode including a plurality of spaced first electrode units, and the second electrode including a plurality of spaced second electrode units, wherein the first electrode units are disposed oppositely to the second electrode units in one-to-one correspondence; a first dielectric layer and a second dielectric layer between the first electrode and the second electrode; a first hydrophobic layer and a second hydrophobic layer between the first dielectric layer and the second dielectric layer, wherein a gap is between the first hydrophobic layer and the second hydrophobic layer.
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公开(公告)号：US11684916B2
公开(公告)日：2023-06-27
申请号：US16632934
申请日：2019-01-09
Inventor： Wenliang Yao , Nan Zhao , Haochen Cui , Peizhi Cai , Fengchun Pang , Yue Geng , Le Gu , Yuelei Xiao , Hui Liao , Yingying Zhao , Chuncheng Che
CPC classification number: B01L3/502715 , C12Q1/686 , B01L2300/0645 , B01L2300/1827
Abstract: A chip for polymerase chain reaction, a method of operating a chip for polymerase chain reaction, and a reaction device are provided. The chip includes: a sample adding region, a mixing region, a temperature cycling region in a sequential arrangement, and at least one driving unit group. The at least one driving unit group includes a plurality of driving units and is configured to drive a liquid drop to move and sequentially pass through the sample adding region, the mixing region, and the temperature cycling region.
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公开(公告)号：US20210331162A1
公开(公告)日：2021-10-28
申请号：US16626490
申请日：2019-07-26
Inventor： Nan Zhao , Peizhi Cai , Haochen Cui , Yuelei Xiao , Fengchun Pang , Le Gu , Yingying Zhao , Hui Liao , Yue Geng , Wenliang Yao
Abstract: A microfluidic apparatus is provided. The microfluidic apparatus includes an electrochromic layer including a plurality of individually independently addressable regions; a microfluidic layer defining a microfluidic channel for allowing a microfluid to pass therethrough; and a plurality of photodetectors configured to detect light transmit through the microfluid. The electrochromic layer is configured to be switched between a first state in which the plurality of individually independently addressable regions of the electrochromic layer are substantially transmissive, and a second state in which at least a first one of the plurality of individually independently addressable regions of the electrochromic layer in a region corresponding to a position of the microfluid is substantially transmissive, at least a second one of the plurality of individually independently addressable regions of the electrochromic layer outside the region corresponding to the position of the microfluid is substantially non-transmissive.
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公开(公告)号：US11986821B2
公开(公告)日：2024-05-21
申请号：US17041544
申请日：2019-11-13
Inventor： Xiaohe Shen , Chungen Yuan , Haochen Cui , Lijiao Hu , Tao Hu , Jing Li , Weiqiong Gan
IPC: B01L3/00
CPC classification number: B01L3/502753 , B01L2300/048 , B01L2300/0681 , B01L2300/0816 , B01L2300/0819 , B01L2300/087 , B01L2300/0877
Abstract: A detection chip is disclosed. The detection chip includes a sample injection structure, a filter structure, and a reaction structure which are sequentially connected. The filter structure includes a first main body, and a first inlet portion and a first outlet portion respectively on two sides of the first main body. A width of the first inlet portion gradually decreases in a direction away from the first main body, and a width of the first outlet portion gradually decreases in a direction away from the first main body.
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Patent Agency Ranking
公开(公告)号：US11691147B2
公开(公告)日：2023-07-04
申请号：US16641126
申请日：2019-07-26
Inventor： Mingyang Lv , Yue Li , Yanchen Li , Jinyu Li , Dawei Feng , Yu Zhao , Dong Wang , Wang Guo , Hailong Wang , Yue Geng , Peizhi Cai , Fengchun Pang , Le Gu , Chuncheng Che , Haochen Cui , Yingying Zhao , Nan Zhao , Yuelei Xiao , Hui Liao
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01L3/502792 , B01L2200/10 , B01L2300/0645 , B01L2300/165 , B01L2400/0427
Abstract: A digital microfluidic chip and a digital microfluidic system. The digital microfluidic chip comprises: an upper substrate and a lower substrate arranged opposite to each other; multiple driving circuits and multiple addressing circuits disposed between the lower substrate and the upper substrate; and a control circuit, electrically connected to the driving circuits and the addressing circuits. The control circuit is configured to apply, in a driving stage, a driving voltage to each driving circuit, such that a droplet is controlled to move inside a droplet accommodation space according to a set path, measure, in a detection stage, after a bias voltage is applied to each addressing circuit, a charge loss amount of each addressing circuit, and to determine the position of the droplet according to the charge loss amount. The charge loss amount of each addressing circuit is related to the intensity of received external light.
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公开(公告)号：US11498068B2
公开(公告)日：2022-11-15
申请号：US16632931
申请日：2019-01-02
Inventor： Wenliang Yao , Haochen Cui , Peizhi Cai , Yuelei Xiao , Fengchun Pang , Yue Geng , Le Gu , Nan Zhao , Hui Liao , Yingying Zhao , Chuncheng Che
IPC: B01L3/00
Abstract: A microfluidic device, a microfluidic detection assembly and a detection method for the microfluidic device. The microfluidic device includes a first substrate and a second substrate; the first substrate and the second substrate are oppositely arranged to define a channel between the first substrate and the second substrate, the channel is configured for liquid to flow, the first substrate includes a base substrate and a plurality of control assemblies which are arranged on the base substrate along an extending direction of the channel, each of the plurality of control assemblies includes: a first electrode, a second electrode and a plurality of coils, and the first electrode is configured to input currents into the plurality of coils, and the plurality of coils are connected in parallel to the second electrode.
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公开(公告)号：US11577246B2
公开(公告)日：2023-02-14
申请号：US16631780
申请日：2019-05-13
Inventor： Le Gu , Peizhi Cai , Fengchun Pang , Yue Geng , Yingying Zhao , Haochen Cui , Yuelei Xiao , Hui Liao , Wenliang Yao , Nan Zhao
Abstract: A microfluidic device and a detection method for the microfluidic device are provided. The microfluidic device includes a driving substrate configured to drive a movement of a droplet; and a position detector configured to detect a position of the droplet on the driving substrate.
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公开(公告)号：US11534758B2
公开(公告)日：2022-12-27
申请号：US16624016
申请日：2018-08-16
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Xue Dong , Yanling Han , Haisheng Wang , Chuncheng Che , Xiaoliang Ding , Yingming Liu , Yuzhen Guo , Wanxian Xu , Peizhi Cai , Haochen Cui , Fengchun Pang
Abstract: A micro-total analysis system and a method thereof are provided. The micro-total analysis system includes: a microfluidic device, configured to accommodate a liquid to be detected; an optical unit, configured to form a first light irradiated to the microfluidic device; and a detection unit, configured to detect the liquid to be detected and output a detection signal to obtain detection information.
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公开(公告)号：US11383238B2
公开(公告)日：2022-07-12
申请号：US16626490
申请日：2019-07-26
Inventor： Nan Zhao , Peizhi Cai , Haochen Cui , Yuelei Xiao , Fengchun Pang , Le Gu , Yingying Zhao , Hui Liao , Yue Geng , Wenliang Yao
Abstract: A microfluidic apparatus is provided. The microfluidic apparatus includes an electrochromic layer including a plurality of individually independently addressable regions; a microfluidic layer defining a microfluidic channel for allowing a microfluid to pass therethrough; and a plurality of photodetectors configured to detect light transmit through the microfluid. The electrochromic layer is configured to be switched between a first state in which the plurality of individually independently addressable regions of the electrochromic layer are substantially transmissive, and a second state in which at least a first one of the plurality of individually independently addressable regions of the electrochromic layer in a region corresponding to a position of the microfluid is substantially transmissive, at least a second one of the plurality of individually independently addressable regions of the electrochromic layer outside the region corresponding to the position of the microfluid is substantially non-transmissive.
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