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1.发明申请公开(公告)号：US20230101892A1
公开(公告)日：2023-03-30
申请号：US18074884
申请日：2022-12-05
Applicant: Biological E Limited
Inventor： Ramesh Venkat Matur , Rajan Sriraman , Deviprasanna Chakka , Satyam Naidu Sureddi , Rajendar Burki , Sreenivasa Rao Ganti , Narender Dev Mantena , Mahima Datla
Abstract: The present disclosure relates to multivalent pneumococcal vaccine compositions comprising capsular pneumococcal polysaccharide serotypes each individually conjugated to carrier proteins. When conjugated, the combination of the capsular pneumococcal polysaccharide serotype and the carrier protein is referred to herein as a polysaccharide-protein conjugate. The pneumococcal vaccine compositions may further comprise one or more of the following: a pharmaceutically acceptable carrier, a pharmaceutically acceptable diluent, a buffer, a preservative, a stabilizer, an adjuvant, and/or a lyophilization excipient. Methods of making and administering the pneumococcal vaccine compositions described herein are also provided.
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2.发明授权公开(公告)号：US11547752B2
公开(公告)日：2023-01-10
申请号：US16369933
申请日：2019-03-29
Applicant: BIOLOGICAL E LIMITED
Inventor： Ramesh Venkat Matur , Rajan Sriraman , Deviprasanna Chakka , Satyam Naidu Sureddi , Rajendar Burki , Sreenivasa Rao Ganti , Narender Dev Mantena , Mahima Datla
IPC: A61K39/09 , A61K39/39 , A61K39/385 , A61K9/00 , A61K39/00
Abstract: The present disclosure relates to multivalent pneumococcal vaccine compositions comprising capsular pneumococcal polysaccharide serotypes each individually conjugated to carrier proteins. When conjugated, the combination of the capsular pneumococcal polysaccharide serotype and the carrier protein is referred to herein as a polysaccharide-protein conjugate. The pneumococcal vaccine compositions may further comprise one or more of the following; a pharmaceutically acceptable carrier, a pharmaceutically acceptable diluent, a buffer, a preservative, a stabilizer, an adjuvant, and/or a lyophilization excipient. Methods of making and administering the pneumococcal vaccine compositions described herein are also provided.
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3.发明申请公开(公告)号：US20190224295A1
公开(公告)日：2019-07-25
申请号：US16369933
申请日：2019-03-29
Applicant: BIOLOGICAL E LIMITED
Inventor： Ramesh Venkat Matur , Rajan Sriraman , Deviprasanna Chakka , Satyam Naidu Sureddi , Rajendar Burki , Sreenivasa Rao Ganti , Narender Dev Mantena , Mahima Datla
Abstract: The present disclosure relates to multivalent pneumococcal vaccine compositions comprising capsular pneumococcal polysaccharide serotypes each individually conjugated to carrier proteins. When conjugated, the combination of the capsular pneumococcal polysaccharide serotype and the carrier protein is referred to herein as a polysaccharide-protein conjugate. The pneumococcal vaccine compositions may further comprise one or more of the following; a pharmaceutically acceptable carrier, a pharmaceutically acceptable diluent, a buffer, a preservative, a stabilizer, an adjuvant, and/or a lyophilization excipient. Methods of making and administering the pneumococcal vaccine compositions described herein are also provided.
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