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公开(公告)号:US09809577B2
公开(公告)日:2017-11-07
申请号:US15103749
申请日:2014-12-11
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , C07D417/14 , C07D495/04 , C07D409/14 , C07D401/14 , C07D513/04 , C07D413/14 , C07D417/12 , C07D487/04
CPC classification number: C07D403/12 , A61K31/506 , C07D239/30 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D513/04 , C07F5/027
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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公开(公告)号:US20160318935A1
公开(公告)日:2016-11-03
申请号:US15103756
申请日:2014-12-11
Applicant: BIOGEN MA INC. , SUNESIS PHARMACEUTICALS, INC.
Inventor: Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Gnanasambandam Kumaravel , Hua Miao , Andrea Bertolotti-Ciarlet , Kevin Otipoby
IPC: C07D487/04 , G01N33/573 , C07D513/04 , C07D473/00 , C07D519/00 , C07D471/04
CPC classification number: C07D487/04 , C07D471/04 , C07D473/00 , C07D513/04 , C07D519/00 , G01N33/573 , G01N2333/9121
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
Abstract translation: 本发明提供了可用作Bruton酪氨酸激酶抑制剂的化合物及其组合物,其表现出所需特性。
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公开(公告)号:US20160311802A1
公开(公告)日:2016-10-27
申请号:US15103749
申请日:2014-12-11
Applicant: Biogen MA Inc. , Sunesis Pharmaceuticals, Inc.
Inventor: Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , C07D495/04 , C07D409/14 , C07D487/04 , C07D513/04 , C07D413/14 , C07D417/12 , C07D417/14 , C07D401/14
CPC classification number: C07D403/12 , A61K31/506 , C07D239/30 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D513/04 , C07F5/027
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
Abstract translation: 本发明提供了可用作Bruton酪氨酸激酶抑制剂的化合物及其组合物,并且其表现出所需特性。
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公开(公告)号:US11572356B2
公开(公告)日:2023-02-07
申请号:US17004411
申请日:2020-08-27
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , C07D417/14 , C07D495/04 , C07D409/14 , C07D401/14 , C07D513/04 , C07D413/14 , A61K31/506 , C07D239/30 , C07F5/02 , C07D417/12 , C07D487/04
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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公开(公告)号:US20190218204A1
公开(公告)日:2019-07-18
申请号:US16108755
申请日:2018-08-22
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , C07F5/02 , C07D239/30 , A61K31/506 , C07D487/04 , C07D513/04 , C07D401/14 , C07D417/14 , C07D417/12 , C07D409/14 , C07D413/14 , C07D495/04
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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公开(公告)号:US10081619B2
公开(公告)日:2018-09-25
申请号:US15699857
申请日:2017-09-08
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , C07D487/04 , C07D401/14 , C07D413/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D495/04 , C07D513/04
CPC classification number: C07D403/12 , A61K31/506 , C07D239/30 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D513/04 , C07F5/027
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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公开(公告)号:US20180093973A1
公开(公告)日:2018-04-05
申请号:US15699857
申请日:2017-12-20
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , C07D487/04 , C07D401/14 , C07D413/14 , C07D409/14 , C07D417/14 , C07D495/04 , C07D513/04 , C07D417/12
CPC classification number: C07D403/12 , A61K31/506 , C07D239/30 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D513/04 , C07F5/027
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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公开(公告)号:US20220332705A1
公开(公告)日:2022-10-20
申请号:US17004411
申请日:2020-08-27
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , A61K31/506 , C07D239/30 , C07F5/02 , C07D401/14 , C07D413/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D495/04 , C07D513/04 , C07D487/04
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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公开(公告)号:US10759783B2
公开(公告)日:2020-09-01
申请号:US16108755
申请日:2018-08-22
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , C07D417/14 , C07D495/04 , C07D409/14 , C07D401/14 , C07D513/04 , C07D413/14 , A61K31/506 , C07D239/30 , C07F5/02 , C07D417/12 , C07D487/04
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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公开(公告)号:US10280169B2
公开(公告)日:2019-05-07
申请号:US15103756
申请日:2014-12-11
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Gnanasambandam Kumaravel , Hua Miao , Andrea Bertolotti-Ciarlet , Kevin Otipoby
IPC: C07D487/04 , C07D473/00 , A61K31/519 , A61K31/522 , C07D471/04 , C07D513/04 , C07D519/00 , G01N33/573
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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