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公开(公告)号：US3871964A
公开(公告)日：1975-03-18
申请号：US34545273
申请日：1973-03-27
申请人： BAYER AG
摘要： Polypeptide materials such as enzymes are rendered waterinsoluble by bonding to a cross-linked copolymer produced by copolymerizing of (A) about 0.1 to 30 wt. % of at least one Alpha , Beta -monoolefinically unsaturated dicarboxylic acid anhydride having about 4 to 9 carbon atoms; (B) about 35 to 90 wt % of at least one di-and/or poly(meth)acrylate of a dial and/or polyol; and (C) about 5 to 60 wt % of at least one hydrophilic monomer.
摘要翻译： 通过与（A）约0.1〜30重量％的共聚而制成的交联共聚物结合，使多肽材料如酶变得不溶于水。 ％的至少一种具有约4至9个碳原子的α，β-单烯属不饱和二羧酸酐; （B）约35至90重量％的至少一种表面和/或多元醇的二 - 和/或聚（甲基）丙烯酸酯; 和（C）约5至60重量％的至少一种亲水性单体。
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公开(公告)号：US3910825A
公开(公告)日：1975-10-07
申请号：US34579273
申请日：1973-03-28
申请人： BAYER AG
IPC分类号： C08F222/04 , C07D499/42 , C08F8/00 , C08F20/20 , C12N11/08 , C12B1/00 , C07G7/02 , C12D13/02
CPC分类号： C12N11/08 , C08F8/00 , C08F20/20 , Y10S530/816 , C08F20/02
摘要： Peptide materials such as enzymes and enzyme inhibitors are rendered water-insoluble by binding the peptide materials to a cross-linked copolymer formed by copolymerizing the following units: (A) about 0.1 to 50 weight percent of at least one Alpha , Beta -monoolefinically unsaturated dicarboxylic acid anhydride having about 4 to 9 carbon atoms and (B) about 99.9 to 50 weight percent of at least one di- and/or poly(meth) acrylate of a diol and/or a polyol.
摘要翻译： 肽材料如酶和酶抑制剂通过将肽材料与通过共聚以下单元形成的交联共聚物结合而变成水不溶性：（A）约0.1至50重量％的至少一种α，β-单烯属不饱和 具有约4至9个碳原子的二羧酸酐和（B）约99.9至50重量％的二醇和/或多元醇的至少一种二 - 和/或聚（甲基）丙烯酸酯。
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