公开(公告)号：US3778352A

公开(公告)日：1973-12-11

申请号：US3778352D

申请日：1973-02-25

Applicant: BAXTER LABORATORIES INC

Inventor： BISHOP R ,  FEKETE L ,  SHANBROM E

IPC: C12Q1/56 ,  G01N13/00 ,  G01N31/14 ,  G01N33/16

CPC classification number: C12Q1/56 ,  G01N2333/75 ,  G01N2333/968

Abstract: PLASMINOGEN IN BLOOD PLASMA IS QUANTITATIVELY DETERMINED BY MEASURING THE DIAMETER OF THE CLEAR RADIAL DIFFUSION ZONE PRODUCED BY THE REACTION OF THE BLOOD PLASMA WITH KNOWN AMOUNTS OF CLOTTED FIBRINOGEN AND PLASMINOGEN SUSPENDED IN A STABLE GEL MEDIUM.

公开(公告)号：US3847545A

公开(公告)日：1974-11-12

申请号：US25458472

申请日：1972-05-18

Applicant: BAXTER LABORATORIES INC

Inventor： SHANBROM E ,  LOUDERBACK A

IPC: G01N33/72 ,  G01N21/06 ,  G01N33/16

CPC classification number: G01N33/52 ,  G01N33/5091 ,  G01N33/721

Abstract: A microcapillary method for the diagnosis of sickle-cell disease in which a sample of unclotted blood is mixed with a reagent comprising phosphate buffer containing a non-ionic surfactant having high water solubility, a hemolyzing agent and a reducing agent, and the reaction results observed macroscopically for turbidity and then a microcapillary sample thereof observed macroscopically for color characteristics.

Abstract translation: 用于诊断镰状细胞病的微毛细管法，其中将未切开血液的样品与包含含有具有高水溶性的非离子表面活性剂的磷酸盐缓冲液，溶血剂和还原剂的试剂混合，并观察反应结果 在宏观上用于浊度，然后宏观地观察微毛细管样品的颜色特性。

公开(公告)号：US3772436A

公开(公告)日：1973-11-13

申请号：US3772436D

申请日：1971-03-01

Applicant: BAXTER LABORATORIES INC

Inventor： SHANBROM E

IPC: A61K51/08 ,  G01N33/00 ,  G01N33/497 ,  A61K27/04

CPC classification number: G01N33/0055 ,  A61K51/08 ,  A61K2123/00 ,  G01N33/497 ,  G01N2333/924

Abstract: A DIGNOSTIC TEST FOR THE DETERMINATION OF LACTASE DEFICIENCY WHICH CONSISTS OF ORAL ADMINISTRATION OF TWO DOSES OF LACTOSE, WHICH MAY BE RADIOLABELED, THE SECOND SAID DOSE INCLUDING A DOSE OF LCTASE ENZYME, AND MEASUREMENT OF THE BLOOD GLUCOSE LEVEL AND/OR THE RADIOLABELED CARBON DIOXIDE IN THE EXPIRED BREATH FOLLOWING EACH SAID ADMINSTRATION.

公开(公告)号：US3783103A

公开(公告)日：1974-01-01

申请号：US3783103D

申请日：1973-02-23

Applicant: BAXTER LABORATORIES INC

Inventor： BISHOP R ,  SHANBROM E

IPC: C12Q1/56 ,  G01N13/00 ,  G01N31/14 ,  G01N33/16

CPC classification number: C12Q1/56 ,  G01N2333/974

Abstract: THROMBIN ACTIVITY IN BLOOD PLASMA IS QUANTITATIVELY DETERMINED BY MEASURING THE DIAMETER OF THE OPAQUE RADIAL DIFFUSION ZONE PRODUCED BY THE REACTION OF THE BLOOD PLASMA WITH UNCLOTTED FIBRINOGEN SUSPENDED IN A STABLE GEL MEDIUM.

公开(公告)号：US3763135A

公开(公告)日：1973-10-02

申请号：US3763135D

申请日：1971-11-08

Applicant: BAXTER LABORATORIES INC

Inventor： SHANBROM E ,  HAINSKI M ,  PAYNE J

IPC: C07K16/06 ,  C07G7/00

CPC classification number: C07K16/065 ,  Y10S530/831

Abstract: THE METHOD OF PREPARING A GAMMA GLOBULIN CONCENTRATE IN HIGH YIELD AND PURITY AND SUITABLE FOR INTRAVENOUS ADMINISTRATION CONSISTING OF THE MULTIPLE FRACTIONATION OF COHN PLASMA FRACTION III WITH POLYETHYLENE GLYCOL 4,000 AT A SERIES OF PREDETERMINED INCREASING CONCENTRATION AND UNDER SELECTED PH CONDITIONS.