公开(公告)号：US10981883B2

公开(公告)日：2021-04-20

申请号：US16694296

申请日：2019-11-25

申请人： BASF Agro B.V.

发明人： Thomas Zierke ,  Joachim Gebhardt ,  Peter Schaefer ,  Uwe Josef Vogelbacher ,  Michael Rack ,  Jan Klaas Lohmann

IPC分类号： C07D301/02 ,  C07D249/08 ,  A01N43/653

摘要： The present invention relates to a process for the preparation of the compounds II from the respective oxo compounds. Furthermore, the invention relates to a process for the preparation of triazole compounds from oxiranes II.

公开(公告)号：US10053436B2

公开(公告)日：2018-08-21

申请号：US15324312

申请日：2015-06-26

申请人： BASF Agro B.V.

发明人： Joachim Gebhardt ,  Manfred Ehresmann ,  Tiziana Chiodo ,  Martin Viertelhaus ,  Roland Goetz

IPC分类号： C07D295/096 ,  C07D249/08 ,  C07D301/02 ,  C07D303/38

CPC分类号： C07D295/096 ,  C07D249/08 ,  C07D301/02 ,  C07D303/38

摘要： The present invention relates to a process for the preparation of oxirane compounds of formula II from keto compounds III using dimethyl sulfide (CH3)2S and dimethylsulfate (CH3)2SO4, forming the reagent IV, trimethylsulfonium methylsulfate [(CH3)3S+ CH3SO4−], in aqueous solution in the presence of potassium hydroxide (KOH).

公开(公告)号：US11072593B2

公开(公告)日：2021-07-27

申请号：US16309478

申请日：2017-06-01

申请人： BASF Agro B.V.

发明人： Joachim Gebhardt ,  Michael Rack ,  Bernd Wolf ,  Stefan Benson ,  Roland Goetz ,  Helmut Kraus

IPC分类号： C07D301/16 ,  C07D303/04 ,  C07D493/08 ,  B01J19/00

摘要： This invention relates to a process for the epoxidation of a tetrasubstituted alkene such as terpinolene to the corresponding epoxide such as terpinolene epoxide by reacting the tetrasubstituted alkene with performic acid prepared in situ from formic acid and hydrogen peroxide in the presence of at least one buffering agent. Further, the invention relates to the use of an oxidizing agent comprising hydrogen peroxide and formic acid for the in-situ epoxidation of a tetrasubstituted alkene.

公开(公告)号：US10882810B2

公开(公告)日：2021-01-05

申请号：US16621655

申请日：2018-06-12

申请人： BASF Agro B.V.

发明人： Joachim Gebhardt ,  Jan Klaas Lohmann ,  David Anderson ,  Michael Rack ,  Roland Goetz

IPC分类号： C07C41/26 ,  C07C43/295 ,  C07D249/08

摘要： The present invention relates to a process for the preparation of the compounds of formula II using a lanthanoid salt.

公开(公告)号：US10118882B2

公开(公告)日：2018-11-06

申请号：US15736974

申请日：2016-06-14

申请人： BASF Agro B.V.

发明人： Joachim Gebhardt ,  Daniel Saelinger ,  Manfred Ehresmann ,  Roland Goetz

IPC分类号： C07C45/00 ,  C07D249/08 ,  C07D301/00 ,  C07C45/64 ,  C07D301/02 ,  C07C49/80 ,  C07C49/84

摘要： The present invention relates to a process for providing substituted phenyl ketones. Furthermore, the invention relates to the use of substituted phenoxyphenyl ketones obtained by the inventive process for the preparation of triazoles.

公开(公告)号：US09981931B2

公开(公告)日：2018-05-29

申请号：US14759779

申请日：2013-12-18

申请人： BASF Agro B.V.

发明人： Thomas Zierke ,  Joachim Gebhardt ,  Peter Schaefer ,  Uwe Josef Vogelbacher ,  Michael Rack ,  Jan Klaas Lohmann

IPC分类号： C07D301/02 ,  C07D249/08 ,  A01N43/653

CPC分类号： C07D301/02 ,  A01N43/653 ,  C07B2200/13 ,  C07D249/08

摘要： The present invention relates to a process for the preparation of the compounds II from the respective oxo compounds. Furthermore, he invention relates to a process for the preparation of triazole compounds from oxiranes II.

公开(公告)号：US10519122B2

公开(公告)日：2019-12-31

申请号：US15805679

申请日：2017-11-07

申请人： BASF Agro B.V.

发明人： Thomas Zierke ,  Joachim Gebhardt ,  Peter Schaefer ,  Uwe Josef Vogelbacher ,  Michael Rack ,  Jan Klaas Lohmann

IPC分类号： C07D301/02 ,  A01N43/653 ,  C07D249/08

摘要： The present invention relates to a process for the preparation of the compounds II from the respective oxo compounds. Furthermore, he invention relates to a process for the preparation of triazole compounds from oxiranes II.

公开(公告)号：US11168060B2

公开(公告)日：2021-11-09

申请号：US16062828

申请日：2016-12-15

申请人： BASF Agro B.V.

发明人： Joachim Gebhardt ,  Daniel Saelinger ,  Manfred Ehresmann ,  Roland Goetz

IPC分类号： C07D249/08

摘要： The present invention relates to a method for producing 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol in high purity. Especially it relates to a method in which this compound is effectively separated from its 1,2,4-triazol-4-yl isomer.

公开(公告)号：US10710969B2

公开(公告)日：2020-07-14

申请号：US16334152

申请日：2017-09-07

申请人： BASF Agro B.V.

发明人： Stefan Benson ,  Michael Rack ,  Bernd Wolf ,  Roland Goetz ,  Joachim Gebhardt ,  Helmut Kraus

IPC分类号： C07D307/00

摘要： This invention relates to a process for preparing (±)-2-exo-(2-Methylbenzyloxy)-1-methyl-4-isopropyl-7-oxabicyclo[2.2.1]heptane of the formula (I) any of its individual enantiomers or any non-racemic mixture thereof, comprising the steps of (a) reacting (±)-2-exo-hydroxy-1-methyl-4-isopropyl-7-oxabicyclo[2.2.1]heptane of the formula (II) any of its individual enantiomers or any non-racemic mixture thereof with a 2-Methylbenzyl compound of the formula (III) wherein X is a leaving group in the presence of at least one base capable of forming water or a C1-C4 alkyl alcohol under the reaction conditions, and at least one inert organic solvent, and (b) simultaneously removing water, the C1-C4 alkyl alcohol or any mixture thereof from the reaction mixture.

公开(公告)号：US10093634B2

公开(公告)日：2018-10-09

申请号：US15105232

申请日：2014-12-08

申请人： BASF Agro B.V.

发明人： Uwe Josef Vogelbacher ,  Joachim Gebhardt ,  Michael Rack ,  Roland Goetz ,  Stefan Fuelster

IPC分类号： C07C45/00 ,  C07C45/64 ,  C07C49/80 ,  C07C249/08 ,  C07C25/13 ,  C07D249/08 ,  C07F3/02

摘要： The present invention relates to a process for the preparation of the ketone compounds (IA) and their use as intermediates for the preparation of triazole fungicides.