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    Space-Filling Intragastric Implants with Fluid Flow
    2.
    发明申请
    Space-Filling Intragastric Implants with Fluid Flow 有权
    具有流体流动的填充内脏植入物

    公开(公告)号：US20150209169A1

    公开(公告)日：2015-07-30

    申请号：US14679413

    申请日：2015-04-06

    申请人： Apollo Endosurgery, Inc.

    发明人： Mitchell H. Babkes ,  Zachary P. Dominguez ,  Justin Schwab

    IPC分类号： A61F5/00

    CPC分类号： A61F5/0036 ,  A61F5/0003 ,  A61F5/0013 ,  A61F5/003 ,  A61F5/0033 ,  A61F5/0073 ,  A61F5/0076 ,  A61F5/0079 ,  A61F5/0086 ,  A61F5/0089 ,  Y10T24/44342 ,  Y10T24/4453 ,  Y10T24/44564

    摘要： A variety of passive intragastric implant devices for obesity treatment are disclosed. Such passive devices do not autonomously change shape, but instead react within the stomach to induce satiety. The devices may take up volume within the stomach, thus reducing the intake capacity. Additionally, the devices may contact areas within the stomach, such as the cardia surrounding the esophageal sphincter, to stimulate satiety-inducing nerves. Also, certain devices slow gastric emptying by blocking or otherwise impeding flow through the pyloric sphincter. A number of devices combine two or more of these satiety-inducing features. Methods of implant are disclosed including compressing the devices within a delivery tube and transorally advancing the devices through the esophagus to be deployed within the stomach. Removal of the devices occurs in the reverse.

    摘要翻译： 公开了用于肥胖症治疗的各种被动胃内植入装置。 这种被动装置不会自主地改变形状，而是在胃内反应以引起饱腹感。 这些装置可能占据胃内的体积，从而降低进气能力。 此外，装置可以接触胃内的区域，例如围绕食管括约肌的贲门，以刺激饱腹引起的神经。 此外，某些装置通过阻塞或阻碍通过幽门括约肌的流动来缓慢胃排空。 许多装置组合了这些饱腹感特征中的两种或更多种。 公开了植入物的方法，包括压缩输送管内的装置并且经由食道经过胃内部署的装置经过前进。 相反的移除设备。

    Reactive intragastric implant devices
    3.
    发明授权
    Reactive intragastric implant devices 有权

    公开(公告)号：US09895246B2

    公开(公告)日：2018-02-20

    申请号：US14621094

    申请日：2015-02-12

    申请人： Apollo Endosurgery, Inc.

    发明人： Zachary Dominguez ,  Justin Schwab ,  Mitchell H. Babkes

    IPC分类号： A61F5/00

    CPC分类号： A61F5/0033 ,  A61F5/0036

    摘要： Transoral implantable devices includes an inflatable body made of a material that permits it to be compressed into a substantially linear transoral delivery configuration and that when implanted in the stomach is adapted to reduce obesity or weight by stimulating the stomach walls of the patient. The body has a plurality of popout features on its surface that reside generally flush with the inflatable body in relaxed, refracted states, and which respond to an increase in pressure within the inflatable body by projecting outward from the body in a stressed, deployed state. The popout features may convert between their retracted and deployed states by movement of rolling diaphragms formed in the inflatable body.

    Intragastric Implants with Collapsible Frames
    4.
    发明申请
    Intragastric Implants with Collapsible Frames 有权
    具有可折叠框架的内部植入物

    公开(公告)号：US20150094753A1

    公开(公告)日：2015-04-02

    申请号：US14519692

    申请日：2014-10-21

    申请人： Apollo Endosurgery, Inc.

    发明人： Zachary Dominguez ,  Mitchell H. Babkes ,  Justin Schwab ,  Christopher S. Mudd ,  Jason Metzner

    IPC分类号： A61F5/00

    CPC分类号： A61F5/0036 ,  A61F5/0003 ,  A61F5/0013 ,  A61F5/003 ,  A61F5/0033 ,  A61F5/0073 ,  A61F5/0076 ,  A61F5/0079 ,  A61F5/0086 ,  A61F5/0089 ,  Y10T24/44342 ,  Y10T24/4453 ,  Y10T24/44564

    摘要： Transoral obesity treatment devices and related methods for operation thereof are described which occupy space within a stomach and/or stimulate the stomach wall. The transoral obesity treatment devices and related methods are intended to assist a patient in maintaining a healthy body weight. Features of the devices include insertion transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The life span of these devices may be material-dependent upon long-term survivability within an acidic stomach, but is intended to last one year or longer. The devices have the capacity to vary in size and are desirably self-actuating in that they change shape and/or volume using internal motors or actuators. The changing character of the devices helps prevent the person's stomach from compensating for the implant, such as sometimes happens with static intragastric devices.

    摘要翻译： 描述了跨腹部肥胖症治疗装置及其相关操作方法，其占据胃内的空间和/或刺激胃壁。 经腹肥胖治疗装置和相关方法旨在帮助患者保持健康的体重。 器件的特征包括经皮插入和无侵入性手术，无相关患者的侵入性手术风险，无明显的患者不适。 这些装置的使用寿命可能依赖于酸性胃内的长期生存能力，但意图持续一年或更长时间。 这些装置具有在尺寸上变化的能力，并且希望是自动致动，因为它们使用内部电动机或致动器改变形状和/或体积。 设备的变化特征有助于防止人的胃部补偿植入物，例如有时会发生静态胃内装置。

    Endolumenal Esophageal Restriction Device
    8.
    发明申请
    Endolumenal Esophageal Restriction Device 有权
    腔内食管限制装置

    公开(公告)号：US20160022460A1

    公开(公告)日：2016-01-28

    申请号：US14874584

    申请日：2015-10-05

    申请人： Apollo Endosurgery, Inc.

    发明人： Justin Schwab ,  Zachary Dominguez ,  Jason Hoover

    IPC分类号： A61F5/00

    CPC分类号： A61F5/0076 ,  A61F5/003 ,  A61F5/005 ,  A61F5/0079 ,  A61F2220/0016 ,  A61F2220/0083

    摘要： Generally described herein are apparatus, systems and methods related to a novel esophageal device implantable in the patient's body and designed to replicate the restrictive and satiety mechanism associated with gastric banding systems known in the art. The device can be a compliant and tubular-shaped and fixated within the gastro-esophageal lumen using tissue anchors.

    摘要翻译： 本文通常描述的是与可植入患者体内的新型食管装置相关的设计，系统和方法，其被设计为复制与本领域已知的胃束带系统相关的限制性和饱腹感机制。 该装置可以是柔顺的和管状的并且使用组织锚定件固定在胃食管腔内。

    Reactive Intragastric Implant Devices
    9.
    发明申请
    Reactive Intragastric Implant Devices 有权
    反应性内植入装置

    公开(公告)号：US20150150700A1

    公开(公告)日：2015-06-04

    申请号：US14621094

    申请日：2015-02-12

    申请人： Apollo Endosurgery, Inc.

    发明人： Zachary Dominguez ,  Justin Schwab ,  Mitchell H. Babkes

    IPC分类号： A61F5/00

    CPC分类号： A61F5/0033 ,  A61F5/0036

    摘要： Transoral implantable devices includes an inflatable body made of a material that permits it to be compressed into a substantially linear transoral delivery configuration and that when implanted in the stomach is adapted to reduce obesity or weight by stimulating the stomach walls of the patient. The body has a plurality of popout features on its surface that reside generally flush with the inflatable body in relaxed, refracted states, and which respond to an increase in pressure within the inflatable body by projecting outward from the body in a stressed, deployed state. The popout features may convert between their retracted and deployed states by movement of rolling diaphragms formed in the inflatable body.

    摘要翻译： 经口植入式装置包括由材料制成的可膨胀体，其允许其被压缩成基本上线性的经腹输送构型，并且当植入在胃中时，可以通过刺激患者的胃壁来减少肥胖或体重。 主体在其表面上具有多个突出特征，其大体上以可松弛的折射状态与可膨胀的身体平齐，并且通过在受压的展开状态从身体向外突出而响应于可充气体内的压力的增加。 弹出功能可以通过形成在可充气体中的滚动隔膜的移动而在其缩回状态和展开状态之间转换。