Multi-functional Adaptive Optics Retinal Imaging
    2.
    发明申请
    Multi-functional Adaptive Optics Retinal Imaging 有权
    多功能自适应光学视网膜成像

    公开(公告)号:US20110234978A1

    公开(公告)日:2011-09-29

    申请号:US13011404

    申请日:2011-01-21

    IPC分类号: A61B3/12 A61B3/14 A61B3/18

    摘要: An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second optical module for the OCT mode includes a second source adapted to provide a second imaging beam for the OCT mode and a second detection device configured to receive a second signal associated with a second image of the retina. The first scanning device is configured to move the first imaging beam along the retina in the slow axis of the SLO mode to acquire the first image and (ii) to move the second imaging beam along the retina in the fast axis of the OCT mode to acquire the second image.

    摘要翻译: 光学装置包括能够以扫描激光检眼镜(SLO)模式和光学相干断层摄影(OCT)模式操作的光学部件的系统。 光学部件的系统包括用于SLO模式的第一光学模块,用于OCT模式的第二光学模块和第一扫描装置。 用于SLO模式的第一光学模块包括适于为SLO模式提供第一成像光束的第一光源和被配置为接收与眼睛的视网膜的第一图像相关联的第一信号的第一检测装置。 用于OCT模式的第二光学模块包括适于为OCT模式提供第二成像光束的第二光源和被配置为接收与视网膜的第二图像相关联的第二信号的第二检测装置。 第一扫描装置被配置成沿着SLO模式的慢轴沿着视网膜移动第一成像光束以获取第一图像,并且(ii)将第二成像光束沿着OCT模式的快轴中的视网膜移动到 获取第二个图像。

    Monitoring blood flow in the retina using a line-scanning laser ophthalmoscope
    3.
    发明授权
    Monitoring blood flow in the retina using a line-scanning laser ophthalmoscope 有权
    使用线扫描激光检眼镜监测视网膜中的血流

    公开(公告)号:US07404640B2

    公开(公告)日:2008-07-29

    申请号:US11043028

    申请日:2005-01-25

    IPC分类号: A61B3/10

    CPC分类号: A61B3/1025

    摘要: Real time, high-speed image stabilization with a retinal tracking scanning laser ophthalmoscope (TSLO) enables new approaches to established diagnostics. Large frequency range (DC to 19 kHz), wide-field (40-deg) stabilized Doppler flowmetry imaging is described for human subjects. The fundus imaging method is a quasi-confocal line-scanning laser ophthalmoscope (LSLO). The retinal tracking system uses a confocal reflectometer with a closed loop optical servo system to lock onto features in the ocular fundus and automatically re-lock after blinks. By performing a slow scan with the laser line imager, frequency-resolved retinal perfusion and vascular flow images can be obtained free of eye motion artifacts.

    摘要翻译: 使用视网膜跟踪扫描激光检眼镜(TSLO)进行实时高速图像稳定,可实现建立诊断的新方法。 对于人类受试者描述了大频率范围(DC至19kHz),宽场(40度)稳定的多普勒血流成像。 眼底成像方法是准共焦线扫描激光检眼镜(LSLO)。 视网膜跟踪系统使用具有闭环光学伺服系统的共焦反射计,以锁定眼底的特征并在眨眼之后自动重新锁定。 通过用激光线成像仪进行慢扫描,可以获得频率分辨的视网膜灌注和血管图像,而不会产生眼睛运动伪影。

    Servo tracking system utilizing phase-sensitive detection of reflectance
variations
    4.
    发明授权
    Servo tracking system utilizing phase-sensitive detection of reflectance variations 失效
    伺服跟踪系统利用反射率变化的相敏检测

    公开(公告)号:US5943115A

    公开(公告)日:1999-08-24

    申请号:US63519

    申请日:1998-04-21

    摘要: Apparatus and methods for tracking a feature on a target surface and continually providing analog corrections to tracking mirrors in real time by utilizing a low-power incoherent tracking beam to detect the movements of a reference feature on the target and confocal reflectometry to monitor the reflection from the tracking beam's current position are described. The apparatus includes a dithering device for dithering the tracking beam in a first and a second direction with an oscillatory motion, a tracking device for controlling the position of a therapeutic beam relative to a target and for controlling the position of the tracking beam relative to a reference feature, a reflectometer for providing an output signal with a phase corresponding to a phase of the reflected tracking beam, and a signal processor for comparing the phase of the reflectometer output signal to the phases of the oscillatory motion and for controlling the tracking device so that the therapeutic beam to tracks relative to the reference feature.

    摘要翻译: 用于跟踪目标表面上的特征的装置和方法,并且通过利用低功率非相干跟踪光束来实时地跟踪反射镜提供模拟校正,以检测目标上的参考特征的运动和共聚焦反射计来监测反射 描述了跟踪光束的当前位置。 该装置包括用于使第一和第二方向上的跟踪光束以振荡运动抖动的抖动装置,用于控制治疗光束相对于目标物的位置并用于控制跟踪光束相对于目标的位置的跟踪装置 参考特征,用于提供具有对应于反射跟踪光束的相位的相位的输出信号的反射计,以及用于将反射计输出信号的相位与振荡运动的相位进行比较并用于控制跟踪装置的信号处理器 治疗束相对于参考特征轨迹。

    Hybrid spectral domain optical coherence tomography line scanning laser ophthalmoscope
    9.
    发明授权
    Hybrid spectral domain optical coherence tomography line scanning laser ophthalmoscope 失效
    混合光谱光学相干断层扫描线扫描激光检眼镜

    公开(公告)号:US07648242B2

    公开(公告)日:2010-01-19

    申请号:US11799315

    申请日:2007-05-01

    IPC分类号: A61B3/10

    摘要: An apparatus for imaging an eye includes a housing and a system of optical components disposed in the housing. The apparatus is capable of operating in a line scanning laser ophthalmoscope (LSLO) mode and an optical coherence tomography (OCT) mode. The system of optical components can include a first source to provide a first beam of light for the OCT mode and a second source to provide a second beam of light for the LSLO mode. In the OCT mode, a first optic is used that (i) scans, using a first surface of the first optic, the first beam of light along a retina of an eye in a first dimension, and (ii) descans, using the first surface, a first light returning from the eye in the first dimension to a detection system in the OCT mode. In the LSLO mode, the first optic is used where the second beam of light passes through a second surface of the first optic.

    摘要翻译: 用于对眼睛进行成像的装置包括壳体和设置在壳体中的光学部件的系统。 该装置能够以线扫描激光检眼镜(LSLO)模式和光学相干断层扫描(OCT)模式进行操作。 光学部件的系统可以包括用于为OCT模式提供第一光束的第一光源和用于为LSLO模式提供第二光束的第二光源。 在OCT模式中,使用第一光学器件,其(i)使用第一光学元件的第一表面沿着第一维度的眼睛的视网膜扫描第一光束,以及(ii)使用第一光学元件 表面,在OCT模式下从第一维度从眼睛返回到检测系统的第一光。 在LSLO模式中,第一光学器件用于第二光束穿过第一光学器件的第二表面。

    Adaptive optics line scanning ophthalmoscope
    10.
    发明授权
    Adaptive optics line scanning ophthalmoscope 有权
    自适应光学线扫描检眼镜

    公开(公告)号:US08201943B2

    公开(公告)日:2012-06-19

    申请号:US12688217

    申请日:2010-01-15

    IPC分类号: A61B3/14 A61B3/00 A61B3/10

    CPC分类号: A61B3/1025

    摘要: A first optical module scans a portion of an eye with a line of light, descans reflected light from the scanned portion of the eye and confocally provides output light in a line focus configuration. A detection device detects the output light and images the portion of the eye. A second optical module detects an optical distortion and corrects the optical distortion in the line of light scanned on the portion of the eye.

    摘要翻译: 第一光学模块用一条光线扫描眼睛的一部分,从而扫描来自眼睛的扫描部分的反射光,并且以线对焦配置共同提供输出光。 检测装置检测输出光并对眼睛的部分进行成像。 第二光学模块检测光学失真并校正在眼睛部分上扫描的光线中的光学失真。