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公开(公告)号：US20190069541A1
公开(公告)日：2019-03-07
申请号：US15767107
申请日：2016-10-11
Applicant: Amsilk GmbH
Inventor： Jens Klein , Lin Romer , Thomas Scheibel , Ute Slotta
IPC: A01N25/34 , A01N63/02 , C07K14/435 , A61L27/22
Abstract: The present invention relates to the use of a biopolymer for reducing the formation of a biofilm, preferably on a substrate, whereby the biopolymer is preferably a polypeptide, such as recombinant spider silk polypeptide. The present invention further relates to methods for producing a substrate which reduces the formation of a biofilm on a surface of said substrate.
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2.发明申请NOVEL BIOPOLYMER HAVING EXCELLENT TENSILE STRENGTH, EXTENSIBILITY AND TOUGHNESS 有权具有优异的拉伸强度，可伸缩性和韧性的新型生物聚合物公开(公告)号：US20130225476A1
公开(公告)日：2013-08-29
申请号：US13742636
申请日：2013-01-16
Applicant: AMSilk GmbH
Inventor： Thomas Scheibel , Felix Bauer
IPC: C07K14/00
CPC classification number: C07K14/00 , A61K38/00 , C07K14/43563
Abstract: The present invention relates to a biopolymer having excellent tensile strength, extensibility and toughness. The present invention further relates to a nucleic acid molecule encoding the biopolymer of the invention, a vector comprising the nucleic acid molecule of the invention and a non-human host transformed with the vector of the invention. Furthermore, the present invention relates to methods for producing a biopolymer of the invention and to foams, films, gels, coatings, particles, capsules, springs or nonwoven mats as well as fibres comprising or consisting of the biopolymer of the invention. The present invention also relates to a method of producing fibres and the biopolymer of the invention for use in medicine, agriculture, cosmetics as well as surface, paper, leather and/or textile processing.
Abstract translation: 本发明涉及具有优异的拉伸强度，伸长性和韧性的生物聚合物。 本发明还涉及编码本发明的生物聚合物的核酸分子，包含本发明的核酸分子的载体和用本发明的载体转化的非人宿主。 此外，本发明涉及制备本发明的生物聚合物和泡沫，薄膜，凝胶，涂层，颗粒，胶囊，弹簧或非织造垫以及由本发明的生物聚合物组成或由其组成的纤维的方法。 本发明还涉及用于医药，农业，化妆品以及表面，纸，皮革和/或纺织品加工的本发明的纤维和生物聚合物的生产方法。
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公开(公告)号：US11827678B2
公开(公告)日：2023-11-28
申请号：US17383926
申请日：2021-07-23
Inventor： Lin Romer , Ute Slotta , Julia Engert , Gerhard Winter , Matthias Lucke , Thomas Scheibel
IPC: A61K39/00 , C07K14/435 , A61K39/385 , A61K47/64 , A61K47/65 , A61P35/00 , A61K47/42 , C12N15/62 , A61K38/00
CPC classification number: C07K14/43518 , A61K39/385 , A61K47/42 , A61K47/646 , A61K47/65 , A61P35/00 , C07K14/43586 , C12N15/62 , A61K38/00 , A61K2039/6031 , A61K2039/627 , C07K2319/40 , C07K2319/50
Abstract: The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
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公开(公告)号：US20190062557A1
公开(公告)日：2019-02-28
申请号：US16126254
申请日：2018-09-10
Applicant: Amsilk GmbH
Inventor： Thomas Scheibel , Axel Leimer , Lin Römer , Lukas Eisoldt , Aniela Heidebrecht , Martha Geffers
IPC: C08L89/00 , C08L89/04 , C08L77/06 , C08L75/04 , C08L67/04 , C08L67/00 , C08L33/08 , B29C47/00 , C08L5/02 , C08L1/02 , C07K14/435 , C08L23/12 , B29L31/00
Abstract: The present invention provides methods for producing a silk protein spinning dope solution suitable for producing high toughness fibres, the thus produced silk protein spinning dope solution, methods for producing fibres using said silk protein spinning dope solution.
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公开(公告)号：US08729238B2
公开(公告)日：2014-05-20
申请号：US13728762
申请日：2012-12-27
Applicant: Amsilk GmbH
Inventor： Thomas Scheibel , Daniel Huemmerich , Andreas Bausch , Kevin Hermanson
CPC classification number: A61K8/11 , A61K8/64 , A61K9/5052 , A61K9/5169 , A61K9/5192 , A61K47/42 , A61K2800/412 , A61K2800/413 , A61Q19/00 , C07K14/43563
Abstract: The present invention is directed to a method of producing nano- and microcapsules from spider silk proteins The invention is further directed to nano- or microcapsules obtainable by this method as well as pharmaceutical, cosmetical and food compositions containing same.
Abstract translation: 本发明涉及从蜘蛛丝蛋白制备纳米和微胶囊的方法。本发明还涉及可通过该方法获得的纳米或微胶囊以及含有它们的药物，化妆品和食品组合物。
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Patent Agency Ranking
公开(公告)号：US20210347832A1
公开(公告)日：2021-11-11
申请号：US17383926
申请日：2021-07-23
Inventor： Lin Romer , Ute Slotta , Julia Engert , Gerhard Winter , Matthias Lucke , Thomas Scheibel
IPC: C07K14/435 , A61K39/385 , A61K47/64 , A61K47/65 , A61P35/00 , A61K47/42 , C12N15/62
Abstract: The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
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公开(公告)号：US20190161522A1
公开(公告)日：2019-05-30
申请号：US16307622
申请日：2017-06-13
Inventor： Lin ROMER , Ute SLOTTA , Julia ENGERT , Gerhard Winter , Matthias Lucke , Thomas Scheibel
IPC: C07K14/435 , A61P35/00 , A61K47/64 , C12N15/62 , A61K39/385 , A61K47/42 , A61K47/65
Abstract: The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
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公开(公告)号：US10072152B2
公开(公告)日：2018-09-11
申请号：US14426316
申请日：2013-09-05
Applicant: Amsilk GmbH
Inventor： Thomas Scheibel , Axel Leimer , Lin Römer , Lukas Eisoldt , Aniela Heidebrecht , Martha Geffers
IPC: C08L89/00 , C07K14/435 , B29C47/00 , C08L1/02 , C08L5/02 , C08L23/12 , C08L33/08 , C08L67/00 , C08L67/04 , C08L75/04 , C08L77/06 , C08L89/04 , B29L31/00
CPC classification number: C08L89/00 , B29C48/022 , B29K2089/00 , B29L2031/731 , C07K14/43518 , C07K14/43586 , C08L1/02 , C08L5/02 , C08L23/12 , C08L33/08 , C08L67/00 , C08L67/04 , C08L75/04 , C08L77/06 , C08L89/04
Abstract: The present invention provides methods for producing a silk protein spinning dope solution suitable for producing high toughness fibers, the thus produced silk protein spinning dope solution, methods for producing fibers using said silk protein spinning dope solution.
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公开(公告)号：US20130136779A1
公开(公告)日：2013-05-30
申请号：US13728762
申请日：2012-12-27
Applicant: Amsilk GmbH
Inventor： Thomas Scheibel , Daniel Huemmerich , Andreas Bausch , Kevin Hermanson
CPC classification number: A61K8/11 , A61K8/64 , A61K9/5052 , A61K9/5169 , A61K9/5192 , A61K47/42 , A61K2800/412 , A61K2800/413 , A61Q19/00 , C07K14/43563
Abstract: The present invention is directed to a method of producing nano- and microcapsules from spider silk proteins The invention is further directed to nano- or microcapsules obtainable by this method as well as pharmaceutical, cosmetical and food compositions containing same.
Abstract translation: 本发明涉及从蜘蛛丝蛋白制备纳米和微胶囊的方法。本发明还涉及可通过该方法获得的纳米或微胶囊以及含有它们的药物，化妆品和食品组合物。
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公开(公告)号：US20240287146A1
公开(公告)日：2024-08-29
申请号：US18499938
申请日：2023-11-01
Inventor： Lin ROMER , Ute SLOTTA , Julia ENGERT , Gerhard Winter , Matthias Lucke , Thomas Scheibel
IPC: C07K14/435 , A61K38/00 , A61K39/00 , A61K39/385 , A61K47/42 , A61K47/64 , A61K47/65 , A61P35/00 , C12N15/62
CPC classification number: C07K14/43518 , A61K39/385 , A61K47/42 , A61K47/646 , A61K47/65 , A61P35/00 , C07K14/43586 , C12N15/62 , A61K38/00 , A61K2039/6031 , A61K2039/627 , C07K2319/40 , C07K2319/50
Abstract: The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
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