公开(公告)号：US20210062156A1

公开(公告)日：2021-03-04

申请号：US17051528

申请日：2019-04-30

Applicant: Amgen Inc.

Inventor： Christopher Kenyon CROWELL ,  Jian W U ,  Athena Denise NAGI ,  Neil KITCHEN ,  Alison Jean GILLESPIE ,  Simina Crina PETROVAN ,  Michael Charles BRANDENSTEIN

IPC: C12N5/071 ,  C07K16/28

Abstract: This invention relates to recombinantly-expressed denosumab molecules and methods for modulating glycan profiles of denosumab molecules.

公开(公告)号：US20240384238A1

公开(公告)日：2024-11-21

申请号：US18779687

申请日：2024-07-22

Applicant: Amgen Inc.

Inventor： Christopher Kenyon CROWELL ,  Jian WU ,  Neil KITCHEN ,  Alison Jean GILLESPIE ,  Simina Crina PETROVAN ,  Michael Charles BRANDENSTEIN ,  Athena Denise Nagi

IPC: C12N5/071 ,  C07K16/28

Abstract: This invention relates to recombinantly-expressed denosumab molecules and methods for modulating glycan profiles of denosumab molecules.