公开(公告)号：US20200221748A1

公开(公告)日：2020-07-16

申请号：US16534711

申请日：2019-08-07

申请人： Allergan Pharmaceuticals International Limited

发明人： Vincenza Pironti ,  Emanuela RONDA ,  Luigi BOLTRI

IPC分类号： A23L29/00 ,  C12N9/20 ,  A61K38/47 ,  A23L33/00 ,  A61K38/46 ,  A61K38/48

摘要： The present invention provides a process for the preparation of a stable and homogeneous liquid composition that is suitable for enteral administration comprising a digestive enzyme product and nutrients from a nutritional formula having specific amount of nutrients. The invention further provides a method for efficiently and effectively administering a therapeutically effective dose of the stable and homogeneous liquid composition by means of an enteral tube.

公开(公告)号：US10993996B2

公开(公告)日：2021-05-04

申请号：US14908642

申请日：2014-08-04

申请人： Allergan Pharmaceuticals International Limited

发明人： Devrim Eren ,  Ruth Thieroff-Ekerdt ,  Luigi Boltri ,  Vincenza Pironti ,  Letizia Ubliglia

IPC分类号： A61K38/54 ,  A61K38/46 ,  A61K9/00 ,  A23L33/195 ,  A23L33/17 ,  A23L33/00 ,  A23L27/60 ,  A61K9/16 ,  A61K9/50

摘要： The present invention is directed to a digestive enzyme composition comprising an enterically coated digestive enzyme product, administrable nutritional medium, and a pharmaceutically acceptable low viscosity oily ingredient. The process for the preparation of the digestive enzyme composition comprises adding an enterically coated digestive enzyme product to a administrable nutritional medium and pharmaceutically acceptable low viscosity oily ingredient. The invention further provides a method for treating a patient suffering from exocrine pancreatic insufficiency related condition comprising administering to the patient a therapeutically effective dose of the digestive enzyme composition by means of a feeding tube.