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公开(公告)号：US07265097B2
公开(公告)日：2007-09-04
申请号：US10224173
申请日：2002-08-20
Applicant: Agis Kydonieus , Clive Elson , Maya Thanou
Inventor： Agis Kydonieus , Clive Elson , Maya Thanou
CPC classification number: A61K31/727 , A61K45/06 , A61K47/24 , A61K47/36 , A61K48/00
Abstract: The present invention provides methods and compositions for delivering a therapeutic agent across a membrane that has limited permeability for the therapeutic agent. The method includes delivering the therapeutic agent to the membrane in a composition which includes a sulphated chitinous polymer as a primary carrier.
Abstract translation: 本发明提供了用于递送治疗剂的方法和组合物，所述方法和组合物跨越对治疗剂具有有限渗透性的膜。 该方法包括将治疗剂递送到包含硫酸化壳多糖聚合物作为主要载体的组合物中的膜上。
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公开(公告)号：US08017595B2
公开(公告)日：2011-09-13
申请号：US11899172
申请日：2007-09-04
Applicant: Agis Kydonieus , Clive Elson , Maya Thanou
Inventor： Agis Kydonieus , Clive Elson , Maya Thanou
CPC classification number: A61K31/727 , A61K45/06 , A61K47/24 , A61K47/36 , A61K48/00
Abstract: The present invention provides methods and compositions for delivering a therapeutic agent across a membrane that has limited permeability for the therapeutic agent. The method includes delivering the therapeutic agent to the membrane in a composition which includes a sulphated chitinous polymer as a primary carrier.
Abstract translation: 本发明提供了用于递送治疗剂的方法和组合物，所述方法和组合物跨越对治疗剂具有有限渗透性的膜。 该方法包括将治疗剂递送到包含硫酸化壳多糖聚合物作为主要载体的组合物中的膜上。
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公开(公告)号：US20080076704A1
公开(公告)日：2008-03-27
申请号：US11899172
申请日：2007-09-04
Applicant: Agis Kydonieus , Clive Elson , Maya Thanou
Inventor： Agis Kydonieus , Clive Elson , Maya Thanou
IPC: A61K38/02 , A61K31/7052 , A61K47/36 , A61K31/727
CPC classification number: A61K31/727 , A61K45/06 , A61K47/24 , A61K47/36 , A61K48/00
Abstract: The present invention provides methods and compositions for delivering a therapeutic agent across a membrane that has limited permeability for the therapeutic agent. The method includes delivering the therapeutic agent to the membrane in a composition which includes a sulphated chitinous polymer as a primary carrier.
Abstract translation: 本发明提供了用于递送治疗剂的方法和组合物，所述方法和组合物跨越对治疗剂具有有限渗透性的膜。 该方法包括将治疗剂递送到包含硫酸化壳多糖聚合物作为主要载体的组合物中的膜上。
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公开(公告)号：US20050214255A1
公开(公告)日：2005-09-29
申请号：US10810742
申请日：2004-03-25
Applicant: Clive Elson , Agis Kydonieus , Susan Henderson
Inventor： Clive Elson , Agis Kydonieus , Susan Henderson
IPC: A61K31/722 , A61K38/16 , A61K38/21 , C07K14/475 , C07K14/56 , C08B37/08
CPC classification number: C08B37/003 , A61K31/722 , A61K38/164 , A61K38/212
Abstract: The invention pertains to N-acetylated, N, O-carboxyalkylchitosans and methods for using the chitosans to treat disorders, such as cancer, nervous system disorders, urinary tract disorders, and reproductive tract disorders.
Abstract translation: 本发明涉及N-乙酰化的N，O-羧基烷基壳多糖和使用壳聚糖治疗诸如癌症，神经系统疾病，尿路疾病和生殖道障碍的疾病的方法。
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公开(公告)号：US07456267B2
公开(公告)日：2008-11-25
申请号：US10810742
申请日：2004-03-25
Applicant: Clive Elson , Agis Kydonieus , Susan Elizabeth Henderson
Inventor： Clive Elson , Agis Kydonieus , Susan Elizabeth Henderson
CPC classification number: C08B37/003 , A61K31/722 , A61K38/164 , A61K38/212
Abstract: The invention pertains to N-acetylated, N, O-carboxyalkylchitosans and methods for using the chitosans to treat disorders, such as cancer, nervous system disorders, urinary tract disorders, and reproductive tract disorders.
Abstract translation: 本发明涉及N-乙酰化的N，O-羧基烷基壳多糖和使用壳聚糖治疗诸如癌症，神经系统疾病，尿路疾病和生殖道障碍的疾病的方法。
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Patent Agency Ranking
公开(公告)号：US07691830B2
公开(公告)日：2010-04-06
申请号：US11059943
申请日：2005-02-17
Applicant: Clive Elson , Agis Kydonieus , Susan Elizabeth Henderson
Inventor： Clive Elson , Agis Kydonieus , Susan Elizabeth Henderson
IPC: A61K31/737
CPC classification number: A61K31/722
Abstract: Methods of treating a subject suffering from a disorder in a mucosal tissue, such as interstitial cystitis; cancer in a mucous membrane such as bladder or vaginal cancer; Crohn's disease; inflammatory bowel disease or colitis, by administering a medicament containing a sulfated chitinous polymer administered topically are described. Pharmaceutical compositions containing the sulfate chitinous polymer are also disclosed.
Abstract translation: 治疗患有粘膜组织中的病症例如间质性膀胱炎的受试者的方法; 膀胱癌或阴道癌等粘膜癌; 克罗恩病; 通过施用含有局部施用的硫酸化几丁质聚合物的药物来描述炎症性肠病或结肠炎。 还公开了含硫酸壳多糖聚合物的药物组合物。
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公开(公告)号：US20060183711A1
公开(公告)日：2006-08-17
申请号：US11059943
申请日：2005-02-17
Applicant: Agis Kydonieus , Clive Elson , Susan Henderson
Inventor： Agis Kydonieus , Clive Elson , Susan Henderson
IPC: A61K31/722
CPC classification number: A61K31/722
Abstract: Methods of treating a subject suffering from a disorder in a mucosal tissue, such as interstitial cystitis; cancer in a mucous membrane such as bladder or vaginal cancer; Crohn's disease; inflammatory bowel disease or colitis, by administering a medicament containing a sulfated chitinous polymer administered topically are described. Pharmaceutical compositions containing the sulfate chitinous polymer are also disclosed.
Abstract translation: 治疗患有粘膜组织中的病症例如间质性膀胱炎的受试者的方法; 膀胱癌或阴道癌等粘膜癌; 克罗恩病; 通过施用含有局部施用的硫酸化几丁质聚合物的药物来描述炎症性肠病或结肠炎。 还公开了含硫酸壳多糖聚合物的药物组合物。
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公开(公告)号：US20100190743A1
公开(公告)日：2010-07-29
申请号：US12754517
申请日：2010-04-05
Applicant: Agis Kydonieus , Clive Elson , Susan Elizabeth Henderson
Inventor： Agis Kydonieus , Clive Elson , Susan Elizabeth Henderson
IPC: A61K31/737 , A61P13/10
CPC classification number: A61K31/722
Abstract: Methods of treating a subject suffering from a disorder in a mucosal tissue, such as interstitial cystitis; cancer in a mucous membrane such as bladder or vaginal cancer; Crohn's disease; inflammatory bowel disease or colitis, by administering a medicament containing a sulfated chitinous polymer administered topically are described. Pharmaceutical compositions containing the sulfate chitinous polymer are also disclosed.
Abstract translation: 治疗患有粘膜组织中的病症例如间质性膀胱炎的受试者的方法; 膀胱癌或阴道癌等粘膜癌; 克罗恩病; 通过施用含有局部施用的硫酸化几丁质聚合物的药物来描述炎症性肠病或结肠炎。 还公开了含硫酸壳多糖聚合物的药物组合物。
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公开(公告)号：US20090203803A1
公开(公告)日：2009-08-13
申请号：US12313014
申请日：2008-11-14
Applicant: Clive Elson , Agis Kydonieus , Susan Elizabeth Henderson
Inventor： Clive Elson , Agis Kydonieus , Susan Elizabeth Henderson
CPC classification number: C08B37/003 , A61K31/722 , A61K38/164 , A61K38/212
Abstract: The invention pertains to N-acetylated, N, O-carboxyalkylchitosans and methods for using the chitosans to treat disorders, such as cancer, nervous system disorders, urinary tract disorders, and reproductive tract disorders.
Abstract translation: 本发明涉及N-乙酰化的N，O-羧基烷基壳多糖和使用壳聚糖治疗诸如癌症，神经系统疾病，尿路疾病和生殖道障碍的疾病的方法。
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公开(公告)号：US09198919B2
公开(公告)日：2015-12-01
申请号：US13123026
申请日：2009-10-07
Applicant: Thomas M. Rossi , Marie Foegh , Agis Kydonieus
Inventor： Thomas M. Rossi , Marie Foegh , Agis Kydonieus
IPC: A61K31/565 , A61K31/57 , A61K9/70 , A61K31/56 , A61K31/535 , A61K31/567
CPC classification number: A61K31/567 , A61K9/0014 , A61K9/7038 , A61K9/7061 , A61K9/7084 , A61K31/535 , A61K31/56 , A61K31/565 , A61K2300/00
Abstract: Dosing regimen for transdermal delivery of hormones comprising a variable treatment cycle and a variable rest interval.
Abstract translation: 用于经皮递送激素的给药方案，包括可变治疗周期和可变休息间隔。
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