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    Molecular analysis system and use thereof
    1.
    发明授权
    Molecular analysis system and use thereof 有权

    公开(公告)号：US11097278B2

    公开(公告)日：2021-08-24

    申请号：US16140101

    申请日：2018-09-24

    申请人： AKONNI BIOSYSTEMS, INC.

    发明人： Christopher G. Cooney ,  Peter Qiang Qu ,  Arial Bueno

    IPC分类号： B01L7/00

    摘要： A molecular testing device comprises a heating and cooling module having a thin-film thermoelectric heating and cooling device, and a removable test module having a combined amplification and hybridization reaction chamber. The reaction chamber comprises a thermo-conductive exterior surface and a microarray on an interior surface. The thin-film thermoelectric heating and cooling device has a heat transfer surface that is adapted to make contact with the thermo-conductive exterior surface of the reaction chamber. The molecular testing device may be used to perform a PCR in the reaction chamber.

    MOLECULAR ANALYSIS SYSTEM AND USE THEREOF
    2.
    发明申请
    MOLECULAR ANALYSIS SYSTEM AND USE THEREOF 审中-公开

    公开(公告)号：US20190022659A1

    公开(公告)日：2019-01-24

    申请号：US16140101

    申请日：2018-09-24

    申请人： AKONNI BIOSYSTEMS, INC.

    发明人： Christopher G. Cooney ,  Peter Qiang Qu ,  Arial Bueno

    IPC分类号： B01L7/00

    摘要： A molecular testing device comprises a heating and cooling module having a thin-film thermoelectric heating and cooling device, and a removable test module having a combined amplification and hybridization reaction chamber. The reaction chamber comprises a thermo-conductive exterior surface and a microarray on an interior surface. The thin-film thermoelectric heating and cooling device has a heat transfer surface that is adapted to make contact with the thermo-conductive exterior surface of the reaction chamber. The molecular testing device may be used to perform a PCR in the reaction chamber.

    Molecular analysis system and use thereof
    3.
    发明授权
    Molecular analysis system and use thereof 有权

    公开(公告)号：US10882046B2

    公开(公告)日：2021-01-05

    申请号：US16107468

    申请日：2018-08-21

    申请人： AKONNI BIOSYSTEMS, INC.

    发明人： Christopher G. Cooney ,  Peter Qiang Qu ,  Arial Bueno

    IPC分类号： B01L7/00

    摘要： A molecular testing device comprises a heating and cooling module having a thin-film thermoelectric heating and cooling device, and a removable test module having a combined amplification and hybridization reaction chamber. The reaction chamber comprises a thermo-conductive exterior surface and a microarray on an interior surface. The thin-film thermoelectric heating and cooling device has a heat transfer surface that is adapted to make contact with the thermo-conductive exterior surface of the reaction chamber. The molecular testing device may be used to perform a PCR in the reaction chamber.

    ROTATING SAMPLE POSITIONING APPARATUS
    4.
    发明申请
    ROTATING SAMPLE POSITIONING APPARATUS 审中-公开

    公开(公告)号：US20190178903A1

    公开(公告)日：2019-06-13

    申请号：US16273563

    申请日：2019-02-12

    申请人： AKONNI BIOSYSTEMS INC.

    发明人： Christopher COONEY ,  Alexander Perov ,  Arial Bueno ,  Charles Daitch

    IPC分类号： G01N35/02 ,  G01N35/00

    摘要： A positioning system for a sample analysis device is disclosed. The positioning system comprises (1) a carousel comprising a platform and a sample loading tray mounted on the platform, and (2) a stage comprising a positioning system for positioning the carousel under the optical path of an imaging system. The sample loading tray is configured for holding a cartridge comprising one or more lateral flow cells (LFCs).

    MOLECULAR ANALYSIS SYSTEM AND USE THEREOF
    8.
    发明申请
    MOLECULAR ANALYSIS SYSTEM AND USE THEREOF 审中-公开
    分子分析系统及其应用

    公开(公告)号：US20150367347A1

    公开(公告)日：2015-12-24

    申请号：US14743389

    申请日：2015-06-18

    申请人： AKONNI BIOSYSTEMS, INC.

    发明人： CHRISTOPHER G. COONEY ,  Peter Qiang Qu ,  Arial Bueno

    IPC分类号： B01L7/00 ,  C12Q1/68

    CPC分类号： B01L7/52 ,  B01L2200/12 ,  B01L2200/147 ,  B01L2300/0636 ,  B01L2300/0819 ,  B01L2300/1822

    摘要： A molecular testing device comprises a heating and cooling module having a thin-film thermoelectric heating and cooling device, and a removable test module having a combined amplification and hybridization reaction chamber. The reaction chamber comprises a thermo-conductive exterior surface and a microarray on an interior surface. The thin-film thermoelectric heating and cooling device has a heat transfer surface that is adapted to make contact with the thermo-conductive exterior surface of the reaction chamber. The molecular testing device may be used to perform a PCR in the reaction chamber.

    摘要翻译： 分子测试装置包括具有薄膜热电加热和冷却装置的加热和冷却模块，以及具有组合的扩增和杂交反应室的可移除测试模块。 反应室包括热导外表面和内表面上的微阵列。 薄膜热电加热和冷却装置具有适于与反应室的热导外表面接触的传热表面。 分子检测装置可用于在反应室中进行PCR。

    Sample analysis system
    9.
    发明授权
    Sample analysis system 有权

    公开(公告)号：US10532352B2

    公开(公告)日：2020-01-14

    申请号：US16374470

    申请日：2019-04-03

    申请人： AKONNI BIOSYSTEMS, INC.

    发明人： Christopher G. Cooney ,  Phillip Belgrader ,  Arial Bueno ,  Steve Garber ,  Nitu Harshendu Thakore ,  Peter Qiang Qu

    IPC分类号： B01L3/00 ,  B01L7/00

    摘要： An integrated sample analysis system is disclosed. The sample analysis system contains (1) a sample preparation/analysis module having sample purification device comprising a monolith that binds specifically to nucleic acids and a sample analysis device comprising a microarray enclosed in a reaction chamber having a hydrophilic interior surface; (2) a temperature control module comprising a thermocycler having a thermally conductive temperature-control bladder; and (3) an imaging device capable of capturing an image of the microarray in the reaction chamber.