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公开(公告)号:US12298210B2
公开(公告)日:2025-05-13
申请号:US18443049
申请日:2024-02-15
Applicant: Agilent Technologies, Inc.
Inventor: Kyle Schleifer , Kristin Briana Bernick , Adrienne Mccampbell , Nicholas M. Sampas , Victor Lim
Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.
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公开(公告)号:US10684199B2
公开(公告)日:2020-06-16
申请号:US15995755
申请日:2018-06-01
Applicant: Agilent Technologies, Inc.
Inventor: Kyle Schleifer , Kristin Briana Bernick , Adrienne Mccampbell , Nicholas M Sampas , Victor Lim
Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.
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公开(公告)号:US11940359B2
公开(公告)日:2024-03-26
申请号:US17564447
申请日:2021-12-29
Applicant: AGILENT TECHNOLOGIES, INC.
Inventor: Kyle Schleifer , Kristin Briana Bernick , Adrienne Mccampbell , Nicholas M. Sampas , Victor Lim
CPC classification number: G01N1/30 , G01N1/06 , G01N1/286 , G01N35/00594 , G06T7/0012 , G01N2001/068 , G01N2001/2873 , G06T2207/10064 , G06T2207/10152 , G06T2207/30024
Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.
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公开(公告)号:US10914658B2
公开(公告)日:2021-02-09
申请号:US16868715
申请日:2020-05-07
Applicant: Agilent Technologies, Inc.
Inventor: Kyle Schleifer , Kristin Briana Bernick , Adrienne Mccampbell , Nicholas M. Sampas , Victor Lim
Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.
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公开(公告)号:US20190099908A1
公开(公告)日:2019-04-04
申请号:US16151297
申请日:2018-10-03
Applicant: Agilent Technologies, Inc.
Inventor: Kyle Schleifer , Carol T Schembri , Young-Ping Hwung
Abstract: The present disclosure related to apparatus and methods for removing waste of debris from a microtome blade, a microtome blade holder, or both. The invention also relates to automated systems and methods for cleaning a microtome.
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公开(公告)号:US20240183763A1
公开(公告)日:2024-06-06
申请号:US18443049
申请日:2024-02-15
Applicant: Agilent Technologies, Inc.
Inventor: Kyle Schleifer , Kristin Briana Bernick , Adrienne Mccampbell , Nicholas M. Sampas , Victor Lim
CPC classification number: G01N1/30 , G01N1/06 , G01N1/286 , G01N35/00594 , G06T7/0012 , G01N2001/068 , G01N2001/2873 , G06T2207/10064 , G06T2207/10152 , G06T2207/30024
Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.
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公开(公告)号:US20220120646A1
公开(公告)日:2022-04-21
申请号:US17564447
申请日:2021-12-29
Applicant: AGILENT TECHNOLOGIES, INC.
Inventor: Kyle Schleifer , Kristin Briana Bernick , Adrienne Mccampbell , Nicholas M. Sampas , Victor Lim
Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.
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公开(公告)号:US20210108995A1
公开(公告)日:2021-04-15
申请号:US17129209
申请日:2020-12-21
Applicant: AGILENT TECHNOLOGIES, INC.
Inventor: Kyle Schleifer , Kristin Briana Bernick , Adrienne Mccampbell , Nicholas M. Sampas , Victor Lim
Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.
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公开(公告)号:US10946543B2
公开(公告)日:2021-03-16
申请号:US16151297
申请日:2018-10-03
Applicant: Agilent Technologies, Inc.
Inventor: Kyle Schleifer , Carol T Schembri , Young-Ping Hwung
Abstract: The present disclosure related to apparatus and methods for removing waste of debris from a microtome blade, a microtome blade holder, or both. The invention also relates to automated systems and methods for cleaning a microtome.
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公开(公告)号:US11243148B2
公开(公告)日:2022-02-08
申请号:US17129209
申请日:2020-12-21
Applicant: AGILENT TECHNOLOGIES, INC.
Inventor: Kyle Schleifer , Kristin Briana Bernick , Adrienne Mccampbell , Nicholas M. Sampas , Victor Lim
Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.
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