公开(公告)号：US20240216917A1

公开(公告)日：2024-07-04

申请号：US18563677

申请日：2022-06-09

申请人： ACOUSORT AB

发明人： Marcus Liljenberg ,  Mikael Evander

IPC分类号： B01L3/00 ,  B01D21/28 ,  G01N1/40

CPC分类号： B01L3/50273 ,  B01D21/283 ,  B01D21/286 ,  B01L3/502761 ,  G01N1/4077 ,  B01L2200/0647 ,  B01L2300/0663 ,  B01L2400/0436 ,  B01L2400/0457 ,  G01N2001/4094

摘要： A method of performing acoustically enhanced sedimentation in a sample of a suspension comprising particles and a fluid is provided. The method comprises the steps of: i. introducing a volume of the sample into an accumulation zone of a microfluidic cavity; ii performing the substeps of: a. during a first time period: subjecting the volume to an acoustic standing wave configured to cause the particles in the volume to accumulate in at least a first region of the volume; b. during a second time period: subjecting the volume to a gravitational field affecting the particles and the fluid so that the particles accumulated in the at least one first region sediment in a first direction in relation to the direction of the gravitational field, thereby removing particles from the volume; and iii. moving the volume in a second direction opposite the first direction by introducing a subsequent volume of the sample into the accumulation zone of the microfluidic cavity. An acoustofluidic system is also provided.