PROTEOGLYCAN-CONTAINING MATERIAL
    1.
    发明申请
    PROTEOGLYCAN-CONTAINING MATERIAL 审中-公开
    含PROTEOGLYCAN的材料

    公开(公告)号:US20120157391A1

    公开(公告)日:2012-06-21

    申请号:US13383987

    申请日:2010-07-16

    IPC分类号: A61K8/64 C07K14/00

    摘要: The present invention was made in view of an object to produce a novel proteoglycan-containing material, and find a novel use and/or a superior effect of the proteoglycan-containing material. The present invention provides a proteoglycan-containing material obtained from fish cartilage, wherein the proteoglycan-containing material comprises an acidic saccharide component having a molecular weight of not less than 2000 kDa. The proteoglycan-containing material provides advantageous effects for skin-moisturizing and skin anti-aging, including a superior skin fibroblast proliferation effect, an effect of enhancing and improving the skin barrier function, an effect of enhancing and improving the skin's capability to produce collagen, a dermis-thickening inhibition effect, and the like.

    摘要翻译: 考虑到产生含有蛋白多糖的新型材料的目的,本发明是鉴定出具有蛋白多糖的材料的新颖用途和/或优异的效果。 本发明提供从软骨获得的含有蛋白聚糖的材料,其中含蛋白多糖的材料包含分子量不小于2000kDa的酸性糖成分。 含有蛋白多糖的材料对皮肤保湿和皮肤抗衰老具有优异的效果,包括优异的皮肤成纤维细胞增殖作用,增强和改善皮肤屏障功能的效果,增强和改善皮肤生产胶原蛋白的能力的作用, 真皮增厚抑制作用等。