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    Sliding reconstitution device for a diluent container
    1.
    发明申请
    Sliding reconstitution device for a diluent container 审中-公开
    用于稀释剂容器的滑动重构装置

    公开(公告)号：US20050137566A1

    公开(公告)日：2005-06-23

    申请号：US10746238

    申请日：2003-12-23

    申请人： Thomas Fowles ,  Robert Weinberg ,  Yann-Per Lee ,  James Rose

    发明人： Thomas Fowles ,  Robert Weinberg ,  Yann-Per Lee ,  James Rose

    IPC分类号： A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61J1/14 ,  A61J1/20 ,  A61B19/00

    CPC分类号： A61J1/1406 ,  A61J1/10 ,  A61J1/1475 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2051 ,  A61J1/2055 ,  A61J1/2089 ,  A61J1/2096

    摘要： The present invention provides a connector device or reconstitution device (10) for placing a first container (12), such as a liquid container (e.g. flexible container or syringe), in fluid communication with a second container (14), such as a drug vial. The connector device (10) has a first sleeve (32) having a first end (36) and a second end (38). The first sleeve (32) has at the first end (36), a first attaching member (30) adapted to attach to the liquid container (12). The connector device (10) also has a second sleeve (34) having a first end (48) and a second end (50). A second attaching member (28) is attached on the second end (50) of the second sleeve (34) and is adapted to attach to the second container (14). The second attaching member (28) has a sealing member (84). A piercing member (76) projects within the sleeves (32,34) for providing a fluid flow path from the first container (12) to the second container (14). The connector device (10) is movable from the inactivated position to the activated position wherein the second sleeve (34) moves axially with respect to the first sleeve (32) and wherein the piercing member places the first container (12) and the second container (14) in fluid communication. The connector device (10) includes structure for preventing premature activation of the connector device (10).

    摘要翻译： 本发明提供了一种连接器装置或重构装置（10），用于将诸如液体容器（例如柔性容器或注射器）的第一容器（12）放置成与第二容器（14）例如药物流体连通 小瓶。 连接器装置（10）具有第一套筒（32），其具有第一端（36）和第二端（38）。 第一套筒（32）在第一端（36）处具有适于附接到液体容器（12）的第一附接构件（30）。 连接器装置（10）还具有具有第一端（48）和第二端（50）的第二套筒（34）。 第二附接构件（28）附接在第二套筒（34）的第二端（50）上并且适于附接到第二容器（14）。 第二安装构件（28）具有密封构件（84）。 刺穿构件（76）突出在套筒（32,34）内，用于提供从第一容器（12）到第二容器（14）的流体流动路径。 连接器装置（10）可从非活动位置移动到启动位置，其中第二套筒（34）相对于第一套筒（32）轴向移动，并且其中刺穿构件将第一容器（12）和第二容器 （14）流体连通。 连接器装置（10）包括用于防止连接器装置（10）过早启动的结构。

    Fluid transport webs exhibiting surface energy gradients
    5.
    发明授权
    Fluid transport webs exhibiting surface energy gradients 失效
    具有表面能量梯度的流体传输网

    公开(公告)号：US06231948B1

    公开(公告)日：2001-05-15

    申请号：US08832715

    申请日：1997-04-11

    申请人： William R. Ouellette ,  Yann-Per Lee ,  A. Renee Haney ,  Frederick M. Langdon ,  John B. Burchnall

    发明人： William R. Ouellette ,  Yann-Per Lee ,  A. Renee Haney ,  Frederick M. Langdon ,  John B. Burchnall

    IPC分类号： B32B310

    CPC分类号： A61F13/5121 ,  A61F13/15731 ,  A61F13/5122 ,  A61F13/5123 ,  A61F13/51311 ,  A61F2013/1543 ,  A61F2013/51061 ,  A61F2013/51066 ,  A61F2013/51147 ,  A61F2013/51165 ,  A61F2013/51173 ,  Y10T428/24273 ,  Y10T428/24322 ,  Y10T428/24331 ,  Y10T428/24802 ,  Y10T428/24942

    摘要： The present invention pertains, in a preferred embodiment, to a fluid-pervious web comprising a first or wearer-contacting surface and a second or garment-facing surface. The web is particularly well suited for use as a topsheet on a disposable absorbent article. The first and second surfaces are separated from one another by an intermediate portion. The first surface of the web provides a structure which exhibits a surface energy less than the surface energy of the intermediate portion. In a preferred embodiment, the web exhibits a plurality of regions of comparatively low surface energy which define surface energy gradients where they interface with higher surface energy web surfaces. More particularly, the present invention pertains to a fluid-pervious web having a plurality of small-scale surface energy gradients which are oriented and located so as to effectively transport fluid away from the first or wearer-contacting surface. The web essentially retains its visual, tactile, and physical properties of the substrate material while achieving the desired surface energy properties. Fluid transport webs according to the present invention preferably include discontinuous, spaced regions defining small scale surface energy gradients on the first surface to aid in small scale fluid movement toward apertures or capillary entrances for transport away from the first surface. Such webs also preferably include small scale surface energy gradients normal to the first surface within a capillary structure to aid in moving fluid away from the first surface and into the capillaries for capillary fluid transport. Web materials suitable for use in the present invention include apertured formed films, apertured and non-apertured nonwoven materials, composite structures, and the like.

    摘要翻译： 在优选实施例中，本发明涉及包含第一或穿用者接触表面和第二或面向衣服表面的透液网。 网特别适合用作一次性吸收制品上的顶片。 第一和第二表面通过中间部分彼此分离。 网的第一表面提供了表现出比中间部分的表面能更小的表面能的结构。 在优选实施例中，幅材呈现出具有相对较低表面能的多个区域，其限定了表面能量梯度，其中它们与较高表面能的幅材表面相接触。 更具体地说，本发明涉及一种具有多个小尺度表面能量梯度的流体可透过的纤维网，它们定向和定位成有效地将流体从第一或穿用者接触表面输送。 纸幅基本上保持其基材材料的视觉，触觉和物理特性，同时实现所需的表面能。 根据本发明的流体输送网优选地包括在第一表面上限定小规模表面能量梯度的不连续的间隔的区域，以帮助小规模的流体朝向孔或毛细管入口移动以便远离第一表面输送。 这样的纤维网还优选地包括垂直于毛细管结构内的第一表面的小规模表面能量梯度，以帮助将流体从第一表面移动并进入用于毛细管流体输送的毛细管中。 适用于本发明的网状材料包括多孔成形薄膜，有孔和无孔非织造材料，复合结构等。

    Fluid transport webs exhibiting surface energy gradients
    6.
    发明授权
    Fluid transport webs exhibiting surface energy gradients 失效
    具有表面能量梯度的流体传输网

    公开(公告)号：US6025049A

    公开(公告)日：2000-02-15

    申请号：US826508

    申请日：1997-04-11

    申请人： William R. Ouellette ,  Yann-Per Lee ,  A. Renee Haney ,  Frederick M. Langdon ,  John B. Burchnall

    发明人： William R. Ouellette ,  Yann-Per Lee ,  A. Renee Haney ,  Frederick M. Langdon ,  John B. Burchnall

    IPC分类号： A61F13/53 ,  A61F13/15 ,  A61F13/49 ,  A61F13/511 ,  B32B5/14 ,  B32B5/18 ,  D04H13/00 ,  B32B3/10

    CPC分类号： A61F13/5121 ,  A61F13/15731 ,  A61F13/5122 ,  A61F13/5123 ,  A61F13/51311 ,  A61F2013/1543 ,  A61F2013/51061 ,  A61F2013/51066 ,  A61F2013/51147 ,  A61F2013/51165 ,  A61F2013/51173 ,  Y10T428/24273 ,  Y10T428/24322 ,  Y10T428/24331 ,  Y10T428/24802 ,  Y10T428/24942

    摘要： The present invention pertains, in a preferred embodiment, to a fluid-pervious web comprising a first or wearer-contacting surface and a second or garment-facing surface. The web is particularly well suited for use as a topsheet on a disposable absorbent article. The first and second surfaces are separated from one another by an intermediate portion. The first surface of the web provides a structure which exhibits a surface energy less than the surface energy of the intermediate portion. In a preferred embodiment, the web exhibits a plurality of regions of comparatively low surface energy which define surface energy gradients where they interface with higher surface energy web surfaces. More particularly, the present invention pertains to a fluid-pervious web having a plurality of small-scale surface energy gradients which are oriented and located so as to effectively transport fluid away from the first or wearer-contacting surface. The web essentially retains its visual, tactile, and physical properties of the substrate material while achieving the desired surface energy properties. Fluid transport webs according to the present invention preferably include discontinuous, spaced regions defining small scale surface energy gradients on the first surface to aid in small scale fluid movement toward apertures or capillary entrances for transport away from the first surface. Such webs also preferably include small scale surface energy gradients normal to the first surface within a capillary structure to aid in moving fluid away from the first surface and into the capillaries for capillary fluid transport. Web materials suitable for use in the present invention include apertured formed films, apertured and non-apertured nonwoven materials, composite structures, and the like.

    摘要翻译： 在优选实施例中，本发明涉及包含第一或穿用者接触表面和第二或面向衣服表面的透液网。 网特别适合用作一次性吸收制品上的顶片。 第一和第二表面通过中间部分彼此分离。 网的第一表面提供了表现出比中间部分的表面能更小的表面能的结构。 在优选实施例中，幅材呈现出具有相对较低表面能的多个区域，其限定了表面能量梯度，其中它们与较高表面能的幅材表面相接触。 更具体地说，本发明涉及一种具有多个小尺度表面能量梯度的流体可透过的纤维网，它们定向和定位成有效地将流体从第一或穿用者接触表面输送。 纸幅基本上保持其基材材料的视觉，触觉和物理特性，同时实现所需的表面能。 根据本发明的流体输送网优选地包括在第一表面上限定小规模表面能量梯度的不连续的间隔的区域，以帮助小规模的流体朝向孔或毛细管入口移动以便远离第一表面输送。 这样的纤维网还优选地包括垂直于毛细管结构内的第一表面的小规模表面能量梯度，以帮助将流体从第一表面移动并进入用于毛细管流体输送的毛细管中。 适用于本发明的网状材料包括多孔成形薄膜，有孔和无孔非织造材料，复合结构等。

    Lubricious or/and wettable or/and anti-thrombin elastomeric gland materials in luer activated devices
    8.
    发明授权
    Lubricious or/and wettable or/and anti-thrombin elastomeric gland materials in luer activated devices 有权
    鲁尔激活装置中的润滑或/和可湿性或/和抗凝血酶弹性体腺体材料

    公开(公告)号：US07857285B2

    公开(公告)日：2010-12-28

    申请号：US11457163

    申请日：2006-07-13

    申请人： Yann-Per Lee ,  Vince Desecki

    发明人： Yann-Per Lee ,  Vince Desecki

    IPC分类号： F16K51/00

    CPC分类号： A61M39/26 ,  A61M2039/0036 ,  F16K1/12 ,  F16L37/28

    摘要： An elastomeric gland is provided for a luer activating device (LAD). and comprises a unique lubricant and/or wetting agent and/or anti-clotting agent incorporated into the elastomer gland during raw material formulation, calendar blending/molding/curing to deliver the surface lubricity and/or wettability and/or avoid slit plane re-knitting and/or gland induced valve stick down of such devices Functional additive chemistries are selected in terms of generated functional performance level, thermal stability against processing, molecular migratability, molecular weight and elastomer substrate of interest. These additives could include lubricants like chemically modified silicone oils and/or wetting agents like silicone-based surfactant. Elastomer gland with wetting agent would ease fluid path priming and minimize micro air bubble adherence to gland surface. Additives may also include anti-clotting agents intended to reduce potential for clot formation within the fluid path and interstitial space of the valve during blood sampling and infusion.

    摘要翻译： 为鲁尔激活装置（LAD）设置弹性体压盖。 并且包含在原料配制期间并入到弹性体压盖中的独特的润滑剂和/或润湿剂和/或抗凝固剂，日历共混/模塑/固化以递送表面润滑性和/或润湿性和/或避免狭缝平面重新 编织和/或腺体诱导阀门粘贴在这些装置上功能添加剂化学物质是根据生产的功能性能水平，热处理稳定性，分子迁移性，分子量和感兴趣的弹性体底物来选择的。 这些添加剂可以包括润滑剂如化学改性的硅油和/或湿润剂如硅氧烷基表面活性剂。 具有润湿剂的弹性体腺体将有助于流体路径引发，并使微气泡附着在腺体表面上最小化。 添加剂还可以包括抗凝血剂，其用于在血液取样和输注期间降低阀的流体路径和间隙空间内凝块形成的可能性。

    LUBRICIOUS OR/AND WETTABLE OR/AND ANTI-THROMBIN ELASTOMERIC GLAND MATERIALS IN LUER ACTIVATED DEVICES
    10.
    发明申请
    LUBRICIOUS OR/AND WETTABLE OR/AND ANTI-THROMBIN ELASTOMERIC GLAND MATERIALS IN LUER ACTIVATED DEVICES 有权
    润滑剂或/和可湿性或/和抗沙门氏菌弹性体材料

    公开(公告)号：US20070012893A1

    公开(公告)日：2007-01-18

    申请号：US11457163

    申请日：2006-07-13

    申请人： Yann-Per Lee ,  Vince Desecki

    发明人： Yann-Per Lee ,  Vince Desecki

    IPC分类号： F16L37/28

    CPC分类号： A61M39/26 ,  A61M2039/0036 ,  F16K1/12 ,  F16L37/28

    摘要： An elastomeric gland is provided for a luer activating device (LAD). and comprises a unique lubricant and/or wetting agent and/or anti-clotting agent incorporated into the elastomer gland during raw material formulation, calendar blending/molding/curing to deliver the surface lubricity and/or wettability and/or avoid slit plane re-knitting and/or gland induced valve stick down of such devices Functional additive chemistries are selected in terms of generated functional performance level, thermal stability against processing, molecular migratability, molecular weight and elastomer substrate of interest. These additives could include lubricants like chemically modified silicone oils and/or wetting agents like silicone-based surfactant. Elastomer gland with wetting agent would ease fluid path priming and minimize micro air bubble adherence to gland surface. Additives may also include anti-clotting agents intended to reduce potential for clot formation within the fluid path and interstitial space of the valve during blood sampling and infusion.

    摘要翻译： 为鲁尔激活装置（LAD）设置弹性体压盖。 并且包含在原料配制期间并入到弹性体压盖中的独特的润滑剂和/或润湿剂和/或抗凝固剂，日历共混/模塑/固化以递送表面润滑性和/或润湿性和/或避免狭缝平面重新 编织和/或腺体诱导阀门粘贴在这些装置上功能添加剂化学物质是根据生产的功能性能水平，热处理稳定性，分子迁移性，分子量和感兴趣的弹性体底物来选择的。 这些添加剂可以包括润滑剂如化学改性的硅油和/或湿润剂如硅氧烷基表面活性剂。 具有润湿剂的弹性体腺体将有助于流体路径引发，并使微气泡附着在腺体表面上最小化。 添加剂还可以包括抗凝血剂，其用于在血液取样和输注期间降低阀的流体路径和间隙空间内凝块形成的可能性。