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    MULTI-FOCUS ULTRASOUND SYSTEM AND METHOD
    1.
    发明申请
    MULTI-FOCUS ULTRASOUND SYSTEM AND METHOD 有权
    多重超声波系统和方法

    公开(公告)号：US20120053468A1

    公开(公告)日：2012-03-01

    申请号：US12873026

    申请日：2010-08-31

    Applicant: Weston Blaine Griffin ,  Douglas Glenn Wildes ,  David Martin Mills ,  Murtuza Lokhandwalla ,  Christopher Robert Hazard ,  Warren Lee ,  Reinhold Bruestle

    Inventor： Weston Blaine Griffin ,  Douglas Glenn Wildes ,  David Martin Mills ,  Murtuza Lokhandwalla ,  Christopher Robert Hazard ,  Warren Lee ,  Reinhold Bruestle

    IPC: A61B8/00

    CPC classification number: A61B8/12 ,  A61B8/4461 ,  A61N7/02 ,  A61N2007/0091

    Abstract: A multi-focus probe that includes a motor communicatively coupled with a lead screw and configured to turn the lead screw about a lengthwise axis of the lead screw, wherein the lead screw includes a length having threads. The probe also includes a lead-screw nut positioned about the lead screw such that the lead-screw nut engages the threads and such that the lead-screw nut and the lead screw can move relative to one another via the threads, a transducer configured to move vertically with the lead screw, and an enclosure surrounding the transducer, wherein the enclosure includes a probe face configured to hold fluid and engage a wave emission target such that waves from the transducer can enter the target. Further, the probe includes a capture feature capable of engaging the lead-screw nut such that the lead-screw nut is vertically fixed relative to the probe face and such that the lead screw moves away from the probe face when rotating within the lead-screw nut in a first direction and moves toward the probe face when rotating within the lead-screw nut in a second direction opposite to the first direction while the lead-screw nut is engaged by the capture feature.

    Abstract translation: 一种多焦点探针，其包括与导螺杆通信地联接并且构造成围绕导螺杆的纵向轴线转动导螺杆的电动机，其中所述导螺杆包括具有螺纹的长度。 该探头还包括一个围绕导螺杆定位的导螺杆螺母，使得导螺杆螺母与螺纹接合，使得导螺杆螺母和导螺杆可以经由螺纹相对于彼此移动，传感器配置成 使用导螺杆和围绕换能器的外壳垂直移动，其中外壳包括被配置为保持流体并接合波发射目标的探针面，使得来自换能器的波可以进入目标。 此外，探针包括捕获特征，其能够接合丝杠螺母，使得丝杠螺母相对于探针面垂直固定，并且当螺杆内的旋转时，导螺杆远离探针面移动 螺母沿第一方向旋转，并且当螺纹螺母与捕获特征接合时，在与第一方向相反的第二方向上在丝杠螺母内旋转时朝向探针面移动。

    Navigation and imaging system sychronized with respiratory and/or cardiac activity
    2.
    发明授权
    Navigation and imaging system sychronized with respiratory and/or cardiac activity 有权
    导航和成像系统与呼吸和/或心脏活动同步

    公开(公告)号：US08057397B2

    公开(公告)日：2011-11-15

    申请号：US11863656

    申请日：2007-09-28

    Applicant: Dun Alex Li ,  Christopher Allen Nafis ,  Douglas Glenn Wildes ,  Vernon Thomas Jensen ,  Weston Blaine Griffin

    Inventor： Dun Alex Li ,  Christopher Allen Nafis ,  Douglas Glenn Wildes ,  Vernon Thomas Jensen ,  Weston Blaine Griffin

    IPC: A61B8/14

    CPC classification number: A61B8/4461 ,  A61B5/062 ,  A61B8/12 ,  A61B8/4254 ,  A61B8/445 ,  A61B8/483

    Abstract: An imaging and navigation system is disclosed herein. The imaging and navigation system includes a computer and an ultrasonic imaging device disposed at least partially within an ultrasound catheter. The ultrasonic imaging device is connected to the computer and is adapted to obtain a generally real time three-dimensional image. The imaging and navigation system also includes a tracking system connected to the computer. The tracking system is adapted to estimate a position of a medical instrument. The imaging and navigation system also includes a display connected to the computer. The display is adapted to depict the generally real time three-dimensional image from the ultrasonic imaging device and to graphically convey the estimated position of the medical instrument.

    Abstract translation: 本文公开了一种成像和导航系统。 成像和导航系统包括计算机和至少部分地设置在超声波导管内的超声成像装置。 超声波成像装置连接到计算机并且适于获得大体上实时的三维图像。 成像和导航系统还包括连接到计算机的跟踪系统。 跟踪系统适于估计医疗器械的位置。 成像和导航系统还包括连接到计算机的显示器。 显示器适于描绘来自超声波成像装置的通常实时的三维图像，并以图形方式传送医疗器械的估计位置。

    Method and apparatus for Operating a Micromotor in a fluid
    3.
    发明申请
    Method and apparatus for Operating a Micromotor in a fluid 有权
    在流体中操作微电机的方法和装置

    公开(公告)号：US20100145310A1

    公开(公告)日：2010-06-10

    申请号：US12315747

    申请日：2008-12-05

    Applicant: Warren Lee ,  Douglas Glenn Wildes ,  Weston Blaine Griffin

    Inventor： Warren Lee ,  Douglas Glenn Wildes ,  Weston Blaine Griffin

    IPC: A61M25/01 ,  A61B8/14

    CPC classification number: A61M25/0082 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4461 ,  A61B2090/3784 ,  A61M25/01 ,  A61M25/0105 ,  A61M25/0116 ,  G01S15/894

    Abstract: A device and a method for sealing a micromotor with an optional associated gearbox are disclosed where, in one aspect of the present invention, a catheter tip comprises: a micromotor; an ultrasound imaging transducer; a gearbox mechanically coupled to the micromotor, the gearbox having a rotatable portion mechanically coupled to the ultrasound imaging transducer array; and a moisture barrier disposed so as to reduce or prevent acoustic coupling fluid from entering both the gearbox and the micromotor.

    Abstract translation: 公开了一种用于与可选的相关联的齿轮箱密封微电机的装置和方法，其中在本发明的一个方面，导管尖端包括：微电机; 超声成像传感器; 机械地联接到所述微型马达的齿轮箱，所述齿轮箱具有机械耦合到所述超声波成像换能器阵列的可旋转部分; 以及设置为减少或防止声耦合流体进入齿轮箱和微型马达的防潮屏障。

    FLUID-FILLABLE ULTRASOUND IMAGING CATHETER TIPS
    4.
    发明申请
    FLUID-FILLABLE ULTRASOUND IMAGING CATHETER TIPS 有权
    流体可充电超声波成像导管

    公开(公告)号：US20080287797A1

    公开(公告)日：2008-11-20

    申请号：US12104223

    申请日：2008-04-16

    Applicant: Warren Lee ,  Douglas Glenn Wildes ,  Weston Blaine Griffin ,  Reinhold Bruestle

    Inventor： Warren Lee ,  Douglas Glenn Wildes ,  Weston Blaine Griffin ,  Reinhold Bruestle

    IPC: A61B8/14 ,  A61B8/12

    CPC classification number: A61B8/4461 ,  A61B8/12 ,  A61B8/4281 ,  A61B8/445 ,  A61B8/483

    Abstract: An imaging catheter tip is presented. The imaging catheter tip includes a housing. Further, the imaging catheter tip includes a transducer assembly located within the housing in a distal portion of the imaging catheter tip. The transducer assembly includes a transducer. In addition, the imaging catheter tip includes a motor located within the housing in a proximal portion of the imaging catheter tip. The motor is configured to facilitate oscillation of the transducer assembly about a longitudinal axis of the imaging catheter tip. The imaging catheter tip also includes a fill tube disposed between the motor and the housing. The fill tube is configured to deliver acoustic coupling fluid to the distal portion of the imaging catheter tip.

    Abstract translation: 呈现成像导管尖端。 成像导管尖端包括壳体。 此外，成像导管尖端包括位于成像导管尖端的远端部分内的壳体内的换能器组件。 换能器组件包括换能器。 此外，成像导管尖端包括位于成像导管尖端的近端部分内的壳体内的马达。 电动机构造成便于换能器组件围绕成像导管尖端的纵向轴线的振荡。 成像导管尖端还包括设置在电动机和壳体之间的填充管。 填充管被配置为将声耦合流体输送到成像导管尖端的远端部分。

    High-throughput methods and systems for processing biological materials
    7.
    发明授权
    High-throughput methods and systems for processing biological materials 有权
    用于处理生物材料的高通量方法和系统

    公开(公告)号：US09034280B2

    公开(公告)日：2015-05-19

    申请号：US12639479

    申请日：2009-12-16

    Applicant: Weston Blaine Griffin ,  Jaydeep Roy ,  Phillip Alexander Shoemaker ,  William Patrick Waters

    Inventor： Weston Blaine Griffin ,  Jaydeep Roy ,  Phillip Alexander Shoemaker ,  William Patrick Waters

    IPC: B01L3/00 ,  A61M1/02 ,  B01D21/26 ,  B03D3/00

    CPC classification number: A61M1/0209 ,  A61M1/0218 ,  A61M1/34 ,  A61M2205/3306 ,  A61M2205/3334 ,  B01D21/26 ,  B03D3/00

    Abstract: A high-throughput system for processing biological material that comprises: a tray that supports a functionally-closed fluid path subsystem comprising, a vessel for containing and enabling the biological material to separate into two or more distinct submaterials; one or more receptacles to receive one or more of the submaterials from the vessel; a filtration device; a conduit through which one or more submaterials are transported between at least the vessel and the filtration device; and a first engagement structure; a processing unit comprising, a pumping device for moving one or more of the submaterials between at least the vessel and the filtration device via the conduit; a second engagement structure corresponding to the first engagement structure; a locking mechanism for at least temporarily holding the tray in a fixed position relative to the processing unit; a control device that automatically starts and stops the pumping device in response to one or more commands.

    Abstract translation: 一种用于处理生物材料的高通量系统，包括：托盘，其支撑功能封闭的流体路径子系统，包括：用于容纳和使所述生物材料分离成两个或更多个不同的子材料的容器; 从容器接收一个或多个子材料的一个或多个容器; 过滤装置; 导管，至少在所述容器和所述过滤装置之间运送一个或多个副材料; 和第一接合结构; 处理单元，包括：泵送装置，用于经由所述导管在至少所述容器和所述过滤装置之间移动所述副材料中的一种或多种; 对应于第一接合结构的第二接合结构; 用于至少临时将所述托盘相对于所述处理单元暂时保持在固定位置的锁定机构; 响应于一个或多个命令自动启动和停止泵送装置的控制装置。

    Methods and systems to prevent punch loss during automated sample processing
    8.
    发明授权
    Methods and systems to prevent punch loss during automated sample processing 有权
    自动化样品处理过程中防止冲孔损失的方法和系统

    公开(公告)号：US08689649B2

    公开(公告)日：2014-04-08

    申请号：US12630899

    申请日：2009-12-04

    Applicant: Philip Alexander Shoemaker ,  Weston Blaine Griffin ,  Erin Jean Finehout

    Inventor： Philip Alexander Shoemaker ,  Weston Blaine Griffin ,  Erin Jean Finehout

    IPC: G01N1/08

    CPC classification number: G01N1/286 ,  G01N2001/288 ,  G01N2035/042

    Abstract: Automated methods and systems for punching out pieces of a porous substrate for biological samples comprising: loading the porous substrate onto a support comprising a die and an opening; moving a receptacle support in at least a z-direction to position a receptacle relative to the support so that an opening in the receptacle is aligned and substantially flush with the opening in the support; actuating a punching head so that the punching head passes through the die, thereby punching a piece out of the porous substrate; and actuating an ejector pin to eject the punched piece from the porous substrate support and into the receptacle aligned with the opening in the support.

    Abstract translation: 用于冲切用于生物样品的多孔基材片的自动方法和系统，包括：将所述多孔基材装载到包括模头和开口的支撑件上; 在至少z方向上移动容器支撑件以相对于支撑件定位容器，使得容器中的开口对齐并且基本上与支撑件中的开口齐平; 致动冲压头，使冲头通过冲模，从而从多孔基材上冲出一块; 并且致动顶针以将冲压件从多孔基底支撑件推出并进入与支撑件中的开口对准的容器中。

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