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    Methods and systems for detecting the hydration of sensors
    4.
    发明授权
    Methods and systems for detecting the hydration of sensors 有权
    检测传感器水合的方法和系统

    公开(公告)号：US08602992B2

    公开(公告)日：2013-12-10

    申请号：US12887465

    申请日：2010-09-21

    申请人： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

    发明人： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

    IPC分类号： A61B5/05 ,  A61B5/00

    CPC分类号： G01N27/403 ,  A61B5/14532 ,  A61B5/1473 ,  A61B2560/0223 ,  A61B2562/02 ,  C12Q1/006 ,  G01N27/327 ,  G01N27/416

    摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

    摘要翻译： 传感器系统包括传感器和传感器电子设备。 传感器包括多个电极。 传感器电子设备包括连接检测装置，电源和延迟电路。 连接检测装置确定传感器电子设备是否连接到传感器并发送连接信号。 延迟电路接收连接信号，等待预设的水合时间，并且在经过预设水合时间之后将调节的电压从电源耦合到传感器中的电极。 或者，传感器电子设备可以包括电检测电路和微控制器。 电检测电路确定多个电极是否水合，并且如果电极是水合的则产生中断。 微控制器接收中断，并将代表电压的信号传送到多个电极的电极。

    REAL-TIME SELF-CALIBRATING SENSOR SYSTEM AND METHOD
    6.
    发明申请
    REAL-TIME SELF-CALIBRATING SENSOR SYSTEM AND METHOD 有权
    实时自校准传感器系统及方法

    公开(公告)号：US20120123690A1

    公开(公告)日：2012-05-17

    申请号：US13340562

    申请日：2011-12-29

    申请人： LU WANG ,  RAJIV SHAH ,  WAYNE A. MORGAN ,  BARRY KEENAN

    发明人： LU WANG ,  RAJIV SHAH ,  WAYNE A. MORGAN ,  BARRY KEENAN

    IPC分类号： G06F19/00 ,  G01N27/403

    CPC分类号： A61B5/1495 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/14865 ,  A61B2560/0223 ,  A61M2005/1726

    摘要： A system and method for calibrating a sensor of a characteristic monitoring system in real time utilizes a self-calibration module for periodic determination of, and compensation for, the IR drop across unwanted resistances in a cell. A current-interrupt switch is used to open the self-calibration module circuit and either measure the IR drop using a high-frequency (MHz) ADC module, or estimate it through linear regression of acquired samples of the voltage across the sensor's working and reference electrodes (Vmeasured) over time. The IR drop is then subtracted from the closed-circuit value of Vmeasured to calculate the overpotential that exists in the cell (Vimportant). Vimportant may be further optimized by subtracting the value of the open-circuit voltage (Voc) across the sensor's working and reference electrodes. The values of Vmeasured and Vimportant are then controlled by respective first and second control units to compensate for the IR drop.

    摘要翻译： 用于校准特征监测系统的传感器的系统和方法实时地利用自校准模块来周期性地确定和补偿细胞中不需要的电阻的IR降。 使用电流中断开关来打开自校准模块电路，并使用高频（MHz）ADC模块测量IR降压，或通过传感器工作和参考电压的采集样本的线性回归进行估计 电极（Vmeasured）随着时间的推移。 然后从Vmeasured的闭路电流值中减去IR降，以计算存在于电池（Vimportant）中的超电势。 可以通过减去传感器的工作参考电极和参考电极之间的开路电压（Voc）的值来进一步优化V重量。 然后由相应的第一和第二控制单元控制V测量和V重量的值以补偿IR下降。

    METHOD OF AND SYSTEM FOR STABILIZATION OF SENSORS
    7.
    发明申请
    METHOD OF AND SYSTEM FOR STABILIZATION OF SENSORS 有权
    传感器稳定方法和系统

    公开(公告)号：US20110125446A1

    公开(公告)日：2011-05-26

    申请号：US13004646

    申请日：2011-01-11

    申请人： RAJIV SHAH ,  Bahar Reghabi ,  James L. Henke ,  Wayne A. Morgan ,  Gopikrishnan Soundararajan ,  David Y. Choy ,  Peter Schultz ,  Udo Hoss

    发明人： RAJIV SHAH ,  Bahar Reghabi ,  James L. Henke ,  Wayne A. Morgan ,  Gopikrishnan Soundararajan ,  David Y. Choy ,  Peter Schultz ,  Udo Hoss

    IPC分类号： G06F19/00 ,  G01R35/00

    CPC分类号： A61B5/1495 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/4839 ,  A61B2560/0223 ,  A61M5/1723 ,  A61M2230/201 ,  G01N27/327 ,  G01N27/3274

    摘要： A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic—cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.

    摘要翻译： 血糖感测系统包括传感器和传感器电子设备。 传感器包括多个电极。 传感器电子设备包括稳定电路。 稳定电路使得第一电压被施加到第一时间帧中的一个电极，并且使得第二电压被施加到第二时间范围中的一个电极。 稳定电路重复施加第一电压和第二电压以继续阳极 - 阴极循环。 传感器电子设备可以包括电源，调节器和电压施加装置，其中电压施加装置从调节器接收调节电压，在第一时间帧向电极施加第一电压，并施加第二电压 第二时间段的电极。

    Implantable sensor electrodes and electronic circuitry
    9.
    发明授权
    Implantable sensor electrodes and electronic circuitry 有权
    可植入传感器电极和电子电路

    公开(公告)号：US07525298B2

    公开(公告)日：2009-04-28

    申请号：US10973525

    申请日：2004-10-25

    申请人： Wayne A. Morgan ,  David Yueh-Hua Choy ,  John Gord ,  Rajiv Shah

    发明人： Wayne A. Morgan ,  David Yueh-Hua Choy ,  John Gord ,  Rajiv Shah

    IPC分类号： G01N27/00 ,  G01N27/26 ,  G01R27/26 ,  A61B5/05

    CPC分类号： A61N1/05 ,  A61B5/042 ,  G01R27/14

    摘要： An electronic circuit for sensing an output of a sensor having at least one electrode pair and circuitry for obtaining and processing the sensor output. The electrode pair may be laid out such that one electrode is wrapped around the other electrode in a U-shaped fashion. The electronic circuitry may include, among other things, a line interface for interfacing with input/output lines, a rectifier in parallel with the line interface, a counter connected to the line interface and a data converter connected to the counter and the electrode pair. The data converter may be a current-to-frequency converter. In addition, the rectifier may derive power for the electronic circuit from communication pulses received on the input/output lines.

    摘要翻译： 一种用于感测具有至少一个电极对的传感器的输出和用于获得和处理传感器输出的电路的电子电路。 可以布置电极对，使得一个电极以U形方式缠绕在另一个电极周围。 电子电路可以包括用于与输入/输出线接口的线路接口，与线路接口并联的整流器，连接到线路接口的计数器和连接到计数器和电极对的数据转换器。 数据转换器可以是电流 - 频率转换器。 此外，整流器可以从输入/输出线上接收的通信脉冲导出电子电路的功率。