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公开(公告)号：US20100111954A1
公开(公告)日：2010-05-06
申请号：US12643166
申请日：2009-12-21
Applicant: Daniel J. Cua , Robert A. Kastelein , Van T. Tsai , Rachel Caspi , Phyllis Silver , Dror Luger
Inventor： Daniel J. Cua , Robert A. Kastelein , Van T. Tsai , Rachel Caspi , Phyllis Silver , Dror Luger
IPC: A61K39/395 , A61P37/06
CPC classification number: C07K16/244 , A61K39/3955 , A61K2039/505 , C07K2317/76
Abstract: Novel methods and drug products for treating autoimmune ocular inflammatory disease are disclosed, which involve administration of agents that antagonize one or both of IL-17 and IL-23 activity.
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Patent Agency Ranking
2.发明申请Use of IL-23 and IL-17 antagonists to treat autoimmune ocular inflammatory disease 审中-公开使用IL-23和IL-17拮抗剂治疗自身免疫性眼炎公开(公告)号：US20080199460A1
公开(公告)日：2008-08-21
申请号：US11512622
申请日：2006-08-30
Applicant: Daniel J. Cua , Robert A. Kastelein , Van T. Tsai , Rachel Caspi , Phyllis Silver , Dror Luger
Inventor： Daniel J. Cua , Robert A. Kastelein , Van T. Tsai , Rachel Caspi , Phyllis Silver , Dror Luger
IPC: A61K39/395 , A61P29/00
CPC classification number: C07K16/244 , A61K39/3955 , A61K2039/505 , C07K2317/76
Abstract: Novel methods and drug products for treating autoimmune ocular inflammatory disease are disclosed, which involve administration of agents that antagonize one or both of IL-17 and IL-23 activity.
Abstract translation: 公开了用于治疗自身免疫性眼部炎性疾病的新方法和药物产品，其包括施用拮抗IL-17和IL-23活性中的一种或两种的药剂。
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公开(公告)号：US06464976B1
公开(公告)日：2002-10-15
申请号：US09653474
申请日：2000-08-31
Applicant: Drake M. LaFace , Amena Rahman , Paul W. Shabram , Van T. Tsai
Inventor： Drake M. LaFace , Amena Rahman , Paul W. Shabram , Van T. Tsai
IPC: A61K3900
CPC classification number: C12N15/86 , A61K35/16 , A61K35/30 , A61K48/00 , A61M1/3486 , A61M1/3496 , C12N2710/10343 , Y10S514/885
Abstract: The present invention provides an apparatus and method to diminish the pre-existing immune response to the administration of a therapeutic virus by the selective elimination of antiviral antibodies from the serum. The present invention provides a chromatographic material for the elimination of such antibodies. The invention further provides plasmapheresis apparatus comprising this material. The invention further provides methods for the employment of such apparatus as part of therapeutic treatment regiments.
Abstract translation: 本发明提供了通过从血清中选择性消除抗病毒抗体来减少预先存在的对施用治疗性病毒的免疫应答的装置和方法。 本发明提供了用于消除这种抗体的色谱材料。 本发明进一步提供了包含该材料的血浆去除装置。 本发明还提供了使用这种装置作为治疗治疗团的一部分的方法。
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4.发明授权Use of IL-23 and IL-17 antagonists to treat autoimmune ocular inflammatory disease 失效使用IL-23和IL-17拮抗剂治疗自身免疫性眼炎公开(公告)号：US08524230B2
公开(公告)日：2013-09-03
申请号：US12643152
申请日：2009-12-21
Applicant: Daniel J. Cua , Robert A. Kastelein , Van T. Tsai , Rachel Caspi , Phyllis Silver
Inventor： Daniel J. Cua , Robert A. Kastelein , Van T. Tsai , Rachel Caspi , Phyllis Silver
IPC: C07K16/244 , A61P29/00 , C07K2316/96 , A61K39/395
CPC classification number: C07K16/244 , A61K39/3955 , A61K2039/505 , C07K2317/76
Abstract: Novel methods and drug products for treating autoimmune ocular inflammatory disease are disclosed, which involve administration of agents that antagonize one or both of IL-17 and IL-23 activity.
Abstract translation: 公开了用于治疗自身免疫性眼部炎性疾病的新方法和药物产品，其包括施用拮抗IL-17和IL-23活性中的一种或两种的药剂。
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5.发明申请USE OF IL-23 AND IL-17 ANTAGONISTS TO TREAT AUTOIMMUNE OCULAR INFLAMMATORY DISEASE 审中-公开使用IL-23和IL-17拮抗剂治疗自身免疫性眼炎性炎症公开(公告)号：US20110142831A1
公开(公告)日：2011-06-16
申请号：US13015900
申请日：2011-01-28
Applicant: Daniel J. Cua , Robert A. Kastelein , Van T. Tsai , Rachel Caspi , Phyllis Silver , Dror Luger
Inventor： Daniel J. Cua , Robert A. Kastelein , Van T. Tsai , Rachel Caspi , Phyllis Silver , Dror Luger
CPC classification number: C07K16/244 , A61K39/3955 , A61K2039/505 , C07K2317/76
Abstract: Novel methods and drug products for treating autoimmune ocular inflammatory disease are disclosed, which involve administration of agents that antagonize one or both of IL-17 and IL-23 activity.
Abstract translation: 公开了用于治疗自身免疫性眼部炎性疾病的新方法和药物产品，其包括施用拮抗IL-17和IL-23活性中的一种或两种的药剂。
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6.发明申请USE OF IL-23 AND IL-17 ANTAGONISTS TO TREAT AUTOIMMUNE OCULAR INFLAMMATORY DISEASE 失效使用IL-23和IL-17拮抗剂治疗自身免疫性眼炎性炎症公开(公告)号：US20100111950A1
公开(公告)日：2010-05-06
申请号：US12643152
申请日：2009-12-21
Applicant: Daniel J. Cua , Robert A. Kastelein , Van T. Tsai , Rachel Caspi , Phyllis Silver , Dror Luger
Inventor： Daniel J. Cua , Robert A. Kastelein , Van T. Tsai , Rachel Caspi , Phyllis Silver , Dror Luger
IPC: A61K39/395 , A61P29/00
CPC classification number: C07K16/244 , A61K39/3955 , A61K2039/505 , C07K2317/76
Abstract: Novel methods and drug products for treating autoimmune ocular inflammatory disease are disclosed, which involve administration of agents that antagonize one or both of IL-17 and IL-23 activity.
Abstract translation: 公开了用于治疗自身免疫性眼部炎性疾病的新方法和药物产品，其包括施用拮抗IL-17和IL-23活性中的一种或两种的药剂。
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