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64 条记录 (耗时 0.043 秒)

    PROCESS
    3.
    发明公开
    PROCESS 审中-公开

    公开(公告)号：US20240052249A1

    公开(公告)日：2024-02-15

    申请号：US18265829

    申请日：2020-12-17

    申请人： UNIVERSITETET I OSLO

    发明人： Unni OLSBYE ,  Jingxiu XIE

    IPC分类号： C10G49/08

    CPC分类号： C10G49/08 ,  C10G2300/4012 ,  C10G2300/4006 ,  C10G2400/20

    摘要： The invention provides a process for preparing olefins from a mixed gaseous feed stream, wherein said mixed gaseous feed stream comprises three or more components selected from the group consisting of carbon dioxide, carbon monoxide, hydrogen, methanol and dimethyl ether, said process comprising contacting the mixed gaseous feed stream with a catalyst of formula (I): M(II)χAl11-χPO4 (I), wherein M(II) is a divalent metal ion; and x=0.002 to 0.5

    Method of producing radionuclides and apparatus therefore
    5.
    发明授权
    Method of producing radionuclides and apparatus therefore 有权

    公开(公告)号：US11335473B2

    公开(公告)日：2022-05-17

    申请号：US16315268

    申请日：2017-07-10

    申请人： UNIVERSITETET I OSLO

    发明人： Gjermund Henriksen ,  Jan Chr. Müller ,  Sunniva Siem ,  Andreas Görgen ,  Bent Wilhelm Schoultz

    IPC分类号： G21G1/10 ,  G21G4/08 ,  G21K5/08 ,  A61K51/02 ,  G21G1/00 ,  H05H6/00

    摘要： The present disclosure provides a method and an apparatus for producing astatine-211 from alpha-particle bombardment of bismuth-209. The disclosure also relates to a method and apparatus of producing other radionuclides from target nuclides. The apparatus includes a plate having a recessed portion. The recessed portion has a generally inert surface of ceramic or metal, preferably aluminium oxide that does not react with molten bismuth. A bismuth target is placed in the recessed portion and held therein by a foil cover. The foil has a melting temperature greater than target nuclide (i.e., for bismuth, >271° C.). The foil and target nuclide are held in the recessed portion by a cover that is fastened over the foil. The cover has an aperture to allow a beam of radiation, such as alpha particles, from a cyclotron or other accelerator to pass through the cover to the foil and target nuclide.

    COMPOUNDS
    6.
    发明申请
    COMPOUNDS 有权

    公开(公告)号：US20210221791A1

    公开(公告)日：2021-07-22

    申请号：US17125474

    申请日：2020-12-17

    申请人： UNIVERSITETET I OSLO

    发明人： Pål RONGVED ,  Ove Alexander Høgmoen ÅSTRAND ,  Ørjan SAMUELSEN ,  Christian SCHNAARS ,  Geir KILDAHL-ANDERSEN

    IPC分类号： C07D401/14 ,  A61P31/04 ,  C07H15/26 ,  C07H19/056 ,  A61K31/44 ,  A61K31/4436 ,  A61K47/54 ,  A61K31/69 ,  A61K31/496 ,  A61K31/706 ,  A61K31/5377 ,  A61K47/61 ,  A61K31/407 ,  A61K31/444

    摘要： The invention provides compounds for use in a method of treating and/or preventing a bacterial infection in a human or non-human mammal, said method comprising administration of said compound in combination with (either simultaneously, separately, or sequentially) a β-lactam antibiotic, wherein said compound has the general formula I: QL-W]X  (I) (wherein: Q is a lipophilic, zinc chelating moiety which is selective for Zn2+ ions and which comprises at least one, preferably two or more (e.g 2, 3 or 4), optionally substituted, unsaturated heterocyclic rings, e.g. 5 or 6-membered heterocyclic rings (such rings preferably include at least one heteroatom selected from N, S and O, preferably N); wherein any optional substituents may be selected from C1-6 alkyl, C1-6 alkoxy, halogen, nitro, cyano, amine, and substituted amine; each L, which may be the same or different, is a covalent bond or a linker; each W, which may be the same or different, is a non-peptidic hydrophilic group which comprises one or more hydroxy groups; and x is an integer from 1 to 3) or a stereoisomer, pharmaceutically acceptable salt or prodrug thereof.

    NETWORK SECURITY
    9.
    发明申请
    NETWORK SECURITY 有权
    网络安全

    公开(公告)号：US20150281211A1

    公开(公告)日：2015-10-01

    申请号：US14431227

    申请日：2013-09-25

    申请人： UNIVERSITETET I OSLO

    发明人： Audun Jøsang ,  Henning Klevjer

    IPC分类号： H04L29/06

    CPC分类号： H04L63/083 ,  G06F21/35 ,  H04L63/10 ,  H04L67/42

    摘要： There is described a method for enabling a user of a client computer to securely access a remote server via a network, which is preferably the Internet, by authenticating the user. The method comprises providing a portable apparatus to the user which may communicate with the client computer. It further involves storing on the portable apparatus user credentials required to enable the user to be authenticated at the server and performing an authentication protocol between the client and the server. The authentication protocol includes the transmission to the server of a digest based at least partially on the user credentials; and the user credentials are stored on the portable apparatus in the form of a digest.

    摘要翻译： 描述了一种使客户计算机的用户能够通过认证用户通过网络（优选为因特网）来安全地访问远程服务器的方法。 该方法包括向用户提供可与客户端计算机通信的便携式设备。 它还涉及在便携式设备上存储使得用户能够在服务器认证并且在客户端和服务器之间执行认证协议所需的用户凭证。 认证协议包括至少部分地基于用户凭证向服务器传送摘要; 并且用户凭证以摘要的形式存储在便携式设备上。

    CYCLIC AMINO COMPOUNDS FOR USE IN THE TREATMENT OF CARDIAC DISORDERS
    10.
    发明申请
    CYCLIC AMINO COMPOUNDS FOR USE IN THE TREATMENT OF CARDIAC DISORDERS 有权
    用于治疗心脏病的CYCLIC AMINO化合物

    公开(公告)号：US20150141456A1

    公开(公告)日：2015-05-21

    申请号：US14549414

    申请日：2014-11-20

    申请人： Universitetet I Oslo

    发明人： Jo Klaveness ,  Kjetil Tasken

    IPC分类号： A61K31/472 ,  A61K31/4439 ,  A61K31/4035

    CPC分类号： A61K31/472 ,  A61K31/4035 ,  A61K31/4439

    摘要： The present invention relates to tertiary amines of formula (I) for use in therapy, particularly for use in treating cardiovascular disorders. The compounds have been found to regulate phospholamban phosphorylation by interfering with the A-kinase anchor protein 18delta (AKAP18δ) binding to the PKA substrate phospholamban. The compounds share a tri(alkylaryl/alkylheteroaryl) amine structure.

    摘要翻译： 本发明涉及用于治疗，特别是用于治疗心血管疾病的式（I）的叔胺。 已经发现这些化合物通过干扰与PKA底物磷胆碱结合的A激酶锚蛋白18delta（AKAP18δ）来调节磷胆碱磷酸化。 该化合物共享三（烷基芳基/烷基杂芳基）胺结构。