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    OCT using spectrally resolved bandwidth
    3.
    发明申请
    OCT using spectrally resolved bandwidth 有权
    OCT使用光谱解析带宽

    公开(公告)号：US20070015969A1

    公开(公告)日：2007-01-18

    申请号：US11446683

    申请日：2006-06-05

    申请人： Marc Feldman ,  Thomas Milner ,  Jung Oh ,  Eunha Kim ,  Karthik Kumar ,  Chris Condit ,  Robert Grant ,  Nate Kemp ,  Jeehyun Kim ,  Shaochen Chen ,  Li-Hsin Han

    发明人： Marc Feldman ,  Thomas Milner ,  Jung Oh ,  Eunha Kim ,  Karthik Kumar ,  Chris Condit ,  Robert Grant ,  Nate Kemp ,  Jeehyun Kim ,  Shaochen Chen ,  Li-Hsin Han

    IPC分类号： A61B1/06

    CPC分类号： A61B5/0073 ,  A61B1/00096 ,  A61B1/00167 ,  A61B1/00172 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/6852

    摘要： The present invention is related to a system for optical coherence tomographic imaging of turbid (i.e., scattering) materials utilizing multiple channels of information. The multiple channels of information may be comprised and encompass spatial, angle, spectral and polarization domains. More specifically, the present invention is related to methods and apparatus for utilizing optical sources, systems or receivers capable of providing (source), processing (system) or recording (receiver) a multiplicity of channels of spectral information for optical coherence tomographic imaging of turbid materials. In these methods and apparatus the multiplicity of channels of spectral information that can be provided by the source, processed by the system, or recorded by the receiver are used to convey simultaneously spatial, spectral or polarimetric information relating to the turbid material being imaged tomographically. The multichannel optical coherence tomographic methods can be incorporated into an endoscopic probe for imaging a patient. The endoscope comprises an optical fiber array and can comprise a plurality of optical fibers adapted to be disposed in the patient. The optical fiber array transmits the light from the light source into the patient, and transmits the light reflected by the patient out of the patient. The plurality of optical fibers in the array are in optical communication with the light source. The multichannel optical coherence tomography system comprises a detector for receiving the light from the array and analyzing the light. The methods and apparatus may be applied for imaging a vessel, biliary, GU and/or GI tract of a patient.

    摘要翻译： 本发明涉及一种利用多信道信息的浑浊（即散射）材料的光学相干断层成像系统。 可以包括多个信道信道并且包括空间，角度，频谱和极化域。 更具体地，本发明涉及用于利用光源，系统或接收机的方法和装置，所述光源，系统或接收机能够提供（源），处理（系统）或记录（接收）多个频谱信息的信道，用于混浊的光学相干断层成像 材料 在这些方法和装置中，可以由源提供的，由系统处理或由接收机记录的光谱信息的多个信道的多样性被用于同时传送与被层析成像的浑浊材料有关的空间，光谱或偏振信息。 多通道光学相干断层摄影方法可以并入用于成像患者的内窥镜探针中。 内窥镜包括光纤阵列，并且可以包括适于设置在患者体内的多根光纤。 光纤阵列将来自光源的光透射到患者体内，并将患者反射的光透射出患者。 阵列中的多根光纤与光源光通信。 多通道光学相干断层摄影系统包括用于从阵列接收光并分析光的检测器。 该方法和装置可以应用于对患者的血管，胆管，GU和/或胃肠道进行成像。

    System and method for interlacing differing coherence length sweeps to improve OCT image quality
    4.
    发明授权
    System and method for interlacing differing coherence length sweeps to improve OCT image quality 有权
    用于交织不同相干长度扫描的系统和方法，以改善OCT图像质量

    公开(公告)号：US09482511B2

    公开(公告)日：2016-11-01

    申请号：US13555108

    申请日：2012-07-21

    申请人： Michael Minneman ,  Jason Ensher ,  Michael Crawford ,  Thomas Milner

    发明人： Michael Minneman ,  Jason Ensher ,  Michael Crawford ,  Thomas Milner

    IPC分类号： G01B9/02

    CPC分类号： G01B9/02004 ,  G01B9/02009 ,  G01B9/02082 ,  G01B9/02087 ,  G01B9/02091

    摘要： A system and method for sweeping electromagnetic radiation over a first coherence length and a second length over a range of wavelengths to generate an image. Electromagnetic radiation having a first coherence length is generated and swept over a range of wavelengths. Electromagnetic radiation having a second coherence length is generated and swept over a range of wavelengths. The electromagnetic radiation is splitting through a reference path and a sample path; Electromagnetic radiation returned from the reference path and the sample path is detected, wherein the detector generates output signals corresponding to the received electromagnetic radiation. In one embodiment, the output signals are processed to generate an image. The image may be interleaved with data corresponding to the electromagnetic radiation having the first coherence length and the second coherence length.

    摘要翻译： 一种用于在波长范围上的第一相干长度和第二长度扫描电磁辐射以产生图像的系统和方法。 产生具有第一相干长度的电磁辐射并扫过波长范围。 产生具有第二相干长度的电磁辐射并扫过波长范围。 电磁辐射通过参考路径和采样路径分裂; 检测从参考路径返回的电磁辐射和采样路径，其中检测器产生对应于所接收的电磁辐射的输出信号。 在一个实施例中，输出信号被处理以产生图像。 图像可以与对应于具有第一相干长度和第二相干长度的电磁辐射的数据进行交织。

    System and method for optimization of coherence length of tunable laser sources
    5.
    发明授权
    System and method for optimization of coherence length of tunable laser sources 有权
    可调激光源相干长度优化的系统和方法

    公开(公告)号：US09008142B2

    公开(公告)日：2015-04-14

    申请号：US13555107

    申请日：2012-07-21

    申请人： Michael Minneman ,  Jason Ensher ,  Thomas Milner

    发明人： Michael Minneman ,  Jason Ensher ,  Thomas Milner

    IPC分类号： H01S5/00 ,  H01S5/065 ,  H01S5/0625 ,  H01S5/14 ,  H01S5/183

    CPC分类号： H01S5/0652 ,  H01S5/06256 ,  H01S5/141 ,  H01S5/183

    摘要： A system and method for adjusting the coherence length of a tunable laser to optimize measurements and reduce artifacts. A tuning element of the laser system modulates, adjusts, or controls parameters associate with the tunable laser, such that the output wavelength of the tunable laser is modulated or adjusted over a wavelength range within a time interval. Modulation of the parameter has the effect of increasing a linewidth of the tunable laser.

    摘要翻译： 用于调整可调谐激光器的相干长度以优化测量并减少伪影的系统和方法。 激光系统的调谐元件调制，调整或控制与可调激光器相关联的参数，使得可调谐激光器的输出波长在时间间隔内在波长范围内被调制或调节。 参数的调制具有增加可调激光器的线宽的作用。

    System and Method for Optimization of Coherence Length of Tunable Laser Sources
    6.
    发明申请
    System and Method for Optimization of Coherence Length of Tunable Laser Sources 有权
    可调谐激光源相干长度优化的系统和方法

    公开(公告)号：US20130044771A1

    公开(公告)日：2013-02-21

    申请号：US13555107

    申请日：2012-07-21

    申请人： Michael Minneman ,  Jason Ensher ,  Thomas Milner

    发明人： Michael Minneman ,  Jason Ensher ,  Thomas Milner

    IPC分类号： H01S3/10 ,  H01S5/06

    CPC分类号： H01S5/0652 ,  H01S5/06256 ,  H01S5/141 ,  H01S5/183

    摘要： A system and method for adjusting the coherence length of a tunable laser to optimize measurements and reduce artifacts. A tuning element of the laser system modulates, adjusts, or controls parameters associate with the tunable laser, such that the output wavelength of the tunable laser is modulated or adjusted over a wavelength range within a time interval. Modulation of the parameter has the effect of increasing a linewidth of the tunable laser.

    摘要翻译： 用于调整可调谐激光器的相干长度以优化测量并减少伪影的系统和方法。 激光系统的调谐元件调制，调整或控制与可调激光器相关联的参数，使得可调谐激光器的输出波长在时间间隔内在波长范围内被调制或调节。 参数的调制具有增加可调激光器的线宽的作用。

    Real-Time Ultrasound Monitoring of Heat-Induced Tissue Interactions
    7.
    发明申请
    Real-Time Ultrasound Monitoring of Heat-Induced Tissue Interactions 审中-公开
    热诱导组织相互作用的实时超声监测

    公开(公告)号：US20090105588A1

    公开(公告)日：2009-04-23

    申请号：US12238753

    申请日：2008-09-26

    申请人： Stanislav Emelianov ,  Thomas Milner ,  Jignesh Shah

    发明人： Stanislav Emelianov ,  Thomas Milner ,  Jignesh Shah

    IPC分类号： A61B18/04 ,  A61B8/00

    CPC分类号： A61B8/00 ,  A61B5/01 ,  A61B5/4869 ,  A61B8/5223 ,  A61B18/20 ,  A61B2017/00084 ,  A61B2017/00106 ,  A61B2090/378 ,  A61N5/0601 ,  A61N5/062

    摘要： The present invention includes an apparatus, method and system for monitoring and controlling radiation therapy, the system including a radiative source that emits energy that enters a tissue and is absorbed at or a near a target site in the tissue to heat the tissue; an ultrasound transmitter directed at the target site, wherein the ultrasound transmitter emits ultrasound signals to the tissue that has been heated by the radiative source; an ultrasound receiver directed at the target site, wherein the ultrasound receiver receives ultrasound signals emitted from the ultrasound transmitter and reflected from the tissue that has been heated by the radiative source; and a signal processor that processes the received ultrasound signal to calculate a tissue composition scan or tissue temperature scan.

    摘要翻译： 本发明包括用于监测和控制放射治疗的装置，方法和系统，所述系统包括放射源，所述辐射源发射进入组织并被组织中的靶位点附近吸收的能量以加热组织; 指向所述目标位置的超声波发射器，其中所述超声波发射器向已被所述辐射源加热的组织发射超声信号; 超声波接收器，其指向所述目标位置，其中所述超声波接收器接收从所述超声波发射器发射并从已被所述辐射源加热的组织反射的超声信号; 以及处理所接收的超声信号以计算组织成分扫描或组织温度扫描的信号处理器。

    ROTATING CATHETER PROBE USING A LIGHT-DRIVE APPARATUS
    10.
    发明申请
    ROTATING CATHETER PROBE USING A LIGHT-DRIVE APPARATUS 有权
    旋转导管探头使用光驱装置

    公开(公告)号：US20070239032A1

    公开(公告)日：2007-10-11

    申请号：US11567244

    申请日：2006-12-06

    申请人： Thomas Milner ,  Nathaniel Kemp

    发明人： Thomas Milner ,  Nathaniel Kemp

    IPC分类号： A61B6/00

    CPC分类号： A61B1/00163 ,  A61B1/0011 ,  A61B1/00172 ,  A61B5/0066 ,  A61B5/6852 ,  Y10T29/49826

    摘要： The invention is a rotating tip catheter-imaging probe where electromagnetic energy is delivered to the distal end of a catheter and converted to mechanical energy using a light drive apparatus. The mechanical energy is then used to rotate a mirror that redirects light in fixed pattern on a sample. The rotating element of the light drive apparatus contains vanes, which rotate about an axis and positioned with bearings to minimize friction. A chamber encompasses the rotating element and is set to a vacuum pressure. The rotational speed of the catheter tip can be controlled by varying the optical power delivered to the vanes, the vacuum pressure in the chamber, or by a braking mechanism applied to the rotating element. The vanes may be shaped in a particular geometry to increase forces on the vanes from thermally driven gas flow.

    摘要翻译： 本发明是旋转尖端导管成像探针，其中电磁能量被传送到导管的远端并且使用光驱动装置转换成机械能。 然后机械能用于旋转将固定模式的光重定向在样品上的反射镜。 光驱装置的旋转元件包含叶片，叶片绕轴线转动并且与轴承一起定位以使摩擦力最小化。 腔室包围旋转元件并被设定为真空压力。 可以通过改变输送到叶片的光功率，腔室中的真空压力，或通过施加到旋转元件的制动机构来控制导管尖端的旋转速度。 叶片可以成形为特定的几何形状以增加来自热驱动气流的叶片上的力。