公开(公告)号：US08597640B2

公开(公告)日：2013-12-03

申请号：US12080756

申请日：2008-04-04

Applicant: Thomas B. Shea ,  Amy Y. Chan-Daniels

Inventor： Thomas B. Shea ,  Amy Y. Chan-Daniels

IPC: A61K38/43 ,  A01N61/00

CPC classification number: A61K36/16 ,  A23L33/10 ,  A23L33/15 ,  A23L33/175 ,  A23V2002/00 ,  A61K31/198 ,  A61K31/205 ,  A61K31/355 ,  A61K31/525 ,  A61K31/7076 ,  A61K35/60 ,  A61K36/73 ,  A61K2300/00 ,  A23V2200/322 ,  A23V2250/712 ,  A23V2250/706 ,  A23V2250/7056 ,  A23V2250/0612 ,  A23V2250/0634 ,  A23V2250/312

Abstract: The present invention provides methods for improving cognitive function, improving mood, and decreasing aggression in a normal adult subject, and in a subject having symptoms characteristic of a neurological disorder, by administration of a nutriceutical formulation of the invention to the subject. The invention additionally features methods of treating neurological disorders, depression, and aggression using nutriceutical formulations. Nutriceutical compositions and formulations for use in the methods of the invention, and kits containing nutriceutical compositions and formulations, are also provided.

公开(公告)号：US08173618B2

公开(公告)日：2012-05-08

申请号：US10898393

申请日：2004-07-23

Applicant: Thomas B. Shea ,  Robert J. Nicolosi ,  Eugene Rogers

Inventor： Thomas B. Shea ,  Robert J. Nicolosi ,  Eugene Rogers

IPC: A61K31/70 ,  A61K31/52 ,  A61K31/195 ,  A61K31/50 ,  A61K31/495 ,  A61K31/22 ,  A61K31/355

CPC classification number: A61K31/525 ,  A23L33/15 ,  A23V2002/00 ,  A61K31/00 ,  A61K31/22 ,  A61K31/355 ,  A61K2300/00 ,  A23V2250/704 ,  A23V2250/712 ,  A23V2250/0612

Abstract: Nutriceutical and pharmaceutical formulations for treating neurodegenerative disorders such as Alzheimer's disease are provided. Nutriceutical formulations include two or more of folate, vitamin E, and acetyl-L-carnitine (ALCAR). Pharmaceutical formulations include two or more of 3-deaza-adenosine (DZA), N-acetyl-L-cysteine (NAC), and S-adenosylmethionine (SAM).

Abstract translation: 提供了用于治疗神经变性疾病如阿尔茨海默病的营养制剂和药物制剂。 营养制剂包括叶酸，维生素E和乙酰基左旋肉碱（ALCAR）中的两种或更多种。 药物制剂包括3-脱氮腺苷（DZA），N-乙酰基-L-半胱氨酸（NAC）和S-腺苷甲硫氨酸（SAM）中的两种或更多种。

公开(公告)号：US20090110745A1

公开(公告)日：2009-04-30

申请号：US12080756

申请日：2008-04-04

Applicant: Thomas B. Shea ,  Amy Y. Chan-Daniels

Inventor： Thomas B. Shea ,  Amy Y. Chan-Daniels

IPC: A61K31/7076 ,  A61P25/00 ,  A61K36/16 ,  A61K36/73 ,  A61K35/60

CPC classification number: A61K36/16 ,  A23L33/10 ,  A23L33/15 ,  A23L33/175 ,  A23V2002/00 ,  A61K31/198 ,  A61K31/205 ,  A61K31/355 ,  A61K31/525 ,  A61K31/7076 ,  A61K35/60 ,  A61K36/73 ,  A61K2300/00 ,  A23V2200/322 ,  A23V2250/712 ,  A23V2250/706 ,  A23V2250/7056 ,  A23V2250/0612 ,  A23V2250/0634 ,  A23V2250/312

Abstract: The present invention provides methods for improving cognitive function, improving mood, and decreasing aggression in a normal adult subject, and in a subject having symptoms characteristic of a neurological disorder, by administration of a nutriceutical formulation of the invention to the subject. The invention additionally features methods of treating neurological disorders, depression, and aggression using nutriceutical formulations. Nutriceutical compositions and formulations for use in the methods of the invention, and kits containing nutriceutical compositions and formulations, are also provided.

Abstract translation: 本发明提供了通过向受试者施用本发明的营养制剂而改善认知功能，改善情绪并减少正常成年受试者和具有神经障碍特征的症状的受试者的侵袭的方法。 本发明另外具有使用营养制剂治疗神经障碍，抑郁和侵略的方法。 还提供了用于本发明方法的营养组合物和制剂，以及含有营养组合物和制剂的试剂盒。

公开(公告)号：US20120252750A1

公开(公告)日：2012-10-04

申请号：US13437487

申请日：2012-04-02

Applicant: Thomas B. SHEA ,  Robert J. NICOLOSI ,  Eugene ROGERS

Inventor： Thomas B. SHEA ,  Robert J. NICOLOSI ,  Eugene ROGERS

IPC: A61K31/7076 ,  A61P25/16 ,  A61P25/28

CPC classification number: A61K31/525 ,  A23L33/15 ,  A23V2002/00 ,  A61K31/00 ,  A61K31/22 ,  A61K31/355 ,  A61K2300/00 ,  A23V2250/704 ,  A23V2250/712 ,  A23V2250/0612

Abstract: Nutriceutical and pharmaceutical formulations for treating neurodegenerative disorders such as Alzheimer's disease are provided. Nutriceutical formulations include two or more of folate, vitamin E, and acetyl-L-carnitine (ALCAR). Pharmaceutical formulations include two or more of 3-deaza-adenosine (DZA), N-acetyl-L-cysteine (NAC), and S-adenosylmethionine (SAM).

Abstract translation: 提供了用于治疗神经变性疾病如阿尔茨海默病的营养制剂和药物制剂。 营养制剂包括叶酸，维生素E和乙酰基左旋肉碱（ALCAR）中的两种或更多种。 药物制剂包括3-脱氮腺苷（DZA），N-乙酰基-L-半胱氨酸（NAC）和S-腺苷甲硫氨酸（SAM）中的两种或更多种。