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公开(公告)号:US20100166733A1
公开(公告)日:2010-07-01
申请号:US12305953
申请日:2006-06-21
申请人: Zurit Levin , Amir Toporik , Michal Ayalon-Soffer , Iris Hecht , Merav Beiman , Dani Eshel , Tali Handelsman
发明人: Zurit Levin , Amir Toporik , Michal Ayalon-Soffer , Iris Hecht , Merav Beiman , Dani Eshel , Tali Handelsman
IPC分类号: A61K39/395 , C07H21/00 , C07K16/00 , C12N15/74 , C12N5/10 , C12P21/00 , A61K31/7088 , A61K45/00 , A61P3/10 , A61P11/06 , A61P11/08 , A61P9/10 , A61P21/00 , A61P37/02
CPC分类号: C07K14/523 , A61K38/00
摘要: Novel MCP-1 splice variant polypeptides and polynucleotides encoding same are provided. Also provided are pharmaceutical compositions comprising the splice variant polypeptides and polynucleotides, vectors and host cells comprising same. The compositions of the present invention are useful to treat various MCP-1 related disorders as well as for diagnosing, determining predisposition and/or prognosis of various disorders.
摘要翻译: 提供了新的MCP-1剪接变体多肽和编码它们的多核苷酸。 还提供了包含剪接变体多肽和多核苷酸,载体和包含其的宿主细胞的药物组合物。 本发明的组合物可用于治疗各种MCP-1相关疾病以及用于诊断,确定各种疾病的倾向和/或预后。
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公开(公告)号:US07601692B2
公开(公告)日:2009-10-13
申请号:US11471652
申请日:2006-06-21
申请人: Zurit Levine , Amir Toporik , Michal Ayalon-Soffer , Iris Hecht , Merav Beiman , Dani Eshel , Tali Handelsman , Sarah Pollock
发明人: Zurit Levine , Amir Toporik , Michal Ayalon-Soffer , Iris Hecht , Merav Beiman , Dani Eshel , Tali Handelsman , Sarah Pollock
CPC分类号: C12Q1/6883 , A61K38/00 , A61K48/00 , C07K14/523 , C12Q2600/156 , C12Q2600/158
摘要: Novel MCP-1 splice variant polypeptides and polynucleotides encoding same are provided. Also provided are pharmaceutical compositions comprising the splice variant polypeptides and polynucleotides, vectors and host cells comprising same. The compositions of the present invention are useful to treat various MCP-1 related disorders as well as for diagnosing, determining predisposition and/or prognosis of various disorders.
摘要翻译: 提供了新的MCP-1剪接变体多肽和编码它们的多核苷酸。 还提供了包含剪接变体多肽和多核苷酸,载体和包含其的宿主细胞的药物组合物。 本发明的组合物可用于治疗各种MCP-1相关疾病以及用于诊断,确定各种疾病的倾向和/或预后。
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公开(公告)号:US20070092484A1
公开(公告)日:2007-04-26
申请号:US11471652
申请日:2006-06-21
申请人: Zurit Levine , Amir Toporik , Michal Ayalon-Soffer , Iris Hecht , Merav Beiman , Dani Eshel , Tali Handelsman , Sarah Pollock
发明人: Zurit Levine , Amir Toporik , Michal Ayalon-Soffer , Iris Hecht , Merav Beiman , Dani Eshel , Tali Handelsman , Sarah Pollock
CPC分类号: C12Q1/6883 , A61K38/00 , A61K48/00 , C07K14/523 , C12Q2600/156 , C12Q2600/158
摘要: Novel MCP-1 splice variant polypeptides and polynucleotides encoding same are provided. Also provided are pharmaceutical compositions comprising the splice variant polypeptides and polynucleotides, vectors and host cells comprising same. The compositions of the present invention are useful to treat various MCP-1 related disorders as well as for diagnosing, determining predisposition and/or prognosis of various disorders.
摘要翻译: 提供了新的MCP-1剪接变体多肽和编码它们的多核苷酸。 还提供了包含剪接变体多肽和多核苷酸的药物组合物,载体和包含其的宿主细胞。 本发明的组合物可用于治疗各种MCP-1相关疾病以及用于诊断,确定各种疾病的倾向和/或预后。
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