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    POLYMER FOR A GLASS IONOMER CEMENT
    2.
    发明申请
    POLYMER FOR A GLASS IONOMER CEMENT 审中-公开
    玻璃离子水泥聚合物

    公开(公告)号：US20130289216A1

    公开(公告)日：2013-10-31

    申请号：US13988049

    申请日：2011-12-20

    申请人： Joachim E. Klee ,  Helmut Ritter ,  Maximilliam Maier ,  Julia Gansel ,  Andreas Facher ,  Oliver Eelsner ,  Sven Pohle

    发明人： Joachim E. Klee ,  Helmut Ritter ,  Maximilliam Maier ,  Julia Gansel ,  Andreas Facher ,  Oliver Eelsner ,  Sven Pohle

    IPC分类号： A61K6/083

    CPC分类号： A61K6/0835 ,  C08F8/00 ,  C08F8/12 ,  C08F8/46 ,  C08F220/06 ,  C08F220/18 ,  C08F220/12 ,  C08L33/08 ,  C08L33/10 ,  C08L33/26

    摘要： A process for producing a water-soluble, hydrolysis-stable, polymerizable polymer, comprising a) a step of copolymerizing a mixture comprising (i) a first copolymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and (ii) a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary amino groups and a second polymerizable organic moiety, for obtaining an amino group containing copolymer; b) a step of coupling to the amino group containing copolymer a compound having a polymerizable moiety and a functional group reactive with an amino group of repeating units derived from the second copolymerizable monomer in the amino group containing copolymer obtained in the first step wherein the optionally protected amino group is deprotected, so that polymerizable pendant groups are linked to the backbone by hydrolysis-stable linking groups, and, optionally, a step of deprotecting the protected carboxylic acid group after step (a) or step (b), for obtaining a polymerizable polymer.

    摘要翻译： 一种制备水溶性，水解稳定的可聚合聚合物的方法，包括：a）使包含（i）包含至少一个任选保护的羧酸基团的第一可共聚单体和第一可聚合有机部分的混合物共聚的步骤，以及 （ii）包含一个或多个任选保护的伯和/或仲氨基和第二可聚合有机部分的第二可共聚单体，用于获得含氨基的共聚物; b）在第一步骤中获得的含氨基的共聚物中偶联到具有可聚合部分的化合物和与衍生自第二可共聚单体的重复单元的氨基反应的官能团的步骤，其中任选地 保护的氨基被脱保护，使得可聚合侧基通过水解稳定的连接基团连接到骨架上，并且任选地在步骤（a）或步骤（b）之后将保护的羧酸基脱保护的步骤，以获得 可聚合聚合物。

    PROCESS FOR THE PREPARATION OF A COMPOSITION COMPRISING HYPERBRANCHED COMPOUNDS
    3.
    发明申请
    PROCESS FOR THE PREPARATION OF A COMPOSITION COMPRISING HYPERBRANCHED COMPOUNDS 审中-公开
    制备包含高分子化合物的组合物的方法

    公开(公告)号：US20120259034A1

    公开(公告)日：2012-10-11

    申请号：US13382784

    申请日：2010-07-06

    申请人： Joachim E. Klee ,  Oliver Elsner ,  Helmet Ritter ,  Sven Pohle ,  Ella Bezdushna

    发明人： Joachim E. Klee ,  Oliver Elsner ,  Helmet Ritter ,  Sven Pohle ,  Ella Bezdushna

    IPC分类号： A61K6/087 ,  C08L77/12 ,  C08L33/02 ,  C08G69/42

    CPC分类号： A61L24/12 ,  A61K6/083 ,  C08G83/005 ,  C08L101/005 ,  C08L33/00

    摘要： A process for the preparation of a composition comprising hyperbranched polymeric compounds, which comprises a step of reacting a mixture comprising one or more compounds of the following formula (I): AR(B)n wherein A and B are functional groups, R is an (n+1)-valent organic group containing one or more thioether groups and n is an integer of at least 2 characterized in that A is an amino group or a hydroxyl group, and B is a carboxylic acid group or an ester or anhydride thereof, under reaction conditions wherein A reacts with B and forms a linking amide group, while A does not react with A and B does not react with B.

    摘要翻译： 一种制备包含超支化聚合物的组合物的方法，其包括使包含一种或多种下式（I）的化合物：AR（B）n的混合物与其中A和B为官能团的混合物反应的步骤，R为 （n + 1）价有机基团，n为至少2的整数，其特征在于A为氨基或羟基，B为羧酸基或其酯或酸酐 在其中A与B反应并形成连接酰胺基的反应条件下，而A不与A反应，B不与B反应。

    Dental composition
    4.
    发明授权
    Dental composition 有权

    公开(公告)号：US09682019B2

    公开(公告)日：2017-06-20

    申请号：US13504949

    申请日：2010-11-02

    申请人： Joachim E. Klee ,  Oliver Elsner ,  Sven Pohle ,  Helmut Ritter ,  Dominika Bernert

    发明人： Joachim E. Klee ,  Oliver Elsner ,  Sven Pohle ,  Helmut Ritter ,  Dominika Bernert

    IPC分类号： A61K6/083 ,  A61K6/00

    CPC分类号： A61K6/0835 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0038 ,  C08L33/00

    摘要： An aqueous dental glass ionomer composition comprising (a) a reactive particulate glass, (b) a linear or branched polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the linear or branched polymer comprising acidic groups has a polymer backbone and optionally pendant groups, (c) optionally dispersed nanoparticles comprising grafted linear or branched polymer chains comprising acidic groups, and having a polymer backbone characterized in that a polymer backbone of the linear or branched polymer of component (b) and/or, if present, the grafted Sinear or branched polymer chains of component (c) are obtainable a process comprising (i) cyclopolymerizing or cyclocopolymerizing one or more compounds of the following formula (I).

    DENTAL COMPOSITION
    5.
    发明申请
    DENTAL COMPOSITION 审中-公开
    牙科成分

    公开(公告)号：US20120149801A1

    公开(公告)日：2012-06-14

    申请号：US13388393

    申请日：2010-03-09

    申请人： Joachim E. Klee ,  Stefan Brugger ,  Helmut Ritter ,  Christoph Weber ,  Oliver Elsner ,  Mareike Bardts ,  Andreas Facher ,  Sven Pohle

    发明人： Joachim E. Klee ,  Stefan Brugger ,  Helmut Ritter ,  Christoph Weber ,  Oliver Elsner ,  Mareike Bardts ,  Andreas Facher ,  Sven Pohle

    IPC分类号： A61K6/083 ,  B82Y5/00

    CPC分类号： A61K6/0835 ,  A61K6/0023 ,  A61K6/0038 ,  C08L33/00

    摘要： An aqueous dental glass ionomer composition comprising (a) a reactive particulate glass, and (b) a linear or branched polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the linear or branched polymer comprising acidic groups has a polymer backbone and optionally pendant side chains, (c) optionally dispersed nanoparticles, and (d) optionally a low molecular compound, characterized in that the glass ionomer composition comprises —SxH groups, wherein x is an integer of from 1 to 6, which crosslink the particulate glass and/or the linear polycarboxylic acid and/or the optional dispersed nanoparticles and/or the optional low molecular compound.

    摘要翻译： 一种水性牙科玻璃离聚物组合物，其包含（a）反应性颗粒玻璃，和（b）包含酸性基团的直链或支链聚合物，其在水泥反应中与颗粒状玻璃反应，由此包含酸性基团的直链或支链聚合物具有 聚合物主链和任选的侧链，（c）任选分散的纳米颗粒，和（d）任选的低分子化合物，其特征在于玻璃离聚物组合物包含-SxH基团，其中x是1至6的整数，其中 交联颗粒状玻璃和/或线性多元羧酸和/或任选的分散纳米颗粒和/或任选的低分子化合物。

    DENTAL COMPOSITION
    8.
    发明申请
    DENTAL COMPOSITION 审中-公开
    牙科成分

    公开(公告)号：US20120238662A1

    公开(公告)日：2012-09-20

    申请号：US13512769

    申请日：2010-12-07

    申请人： Joachim E. Klee ,  Helmut Ritter ,  Sven Pohle ,  Oliver Elsner ,  Mareike Bardts

    发明人： Joachim E. Klee ,  Helmut Ritter ,  Sven Pohle ,  Oliver Elsner ,  Mareike Bardts

    IPC分类号： C08G63/91 ,  A61K6/00

    CPC分类号： A61K6/0835 ,  A61K6/0038 ,  A61K6/083 ,  C08F218/06 ,  C08F265/02 ,  C08F267/04 ,  C08L33/00

    摘要： Dental cement composition comprising a polymerizable polyacidic polymer having repeating units in the polymer backbone, which are represented by the following formula (I)1 (II), and/or (III): wherein X represents O, S, or NR′, whereby R′ represents a hydrogen atom or a straight or branched C1-C6 alkyl group, C3-C6 cycloalkyl group, or C4-C8 cycloalkylalkyl group, Y a group of the following formula (IV), wherein each of L1, L2, L3 and L4, which are independent from each other represents a single bond, a straight or branched C1-C6 alkylene group, a straight or branched C1-C6 alkenylene, or a straight or branched C1-C20 alkylene group which includes 1 to 8 atoms selected from oxygen and sulfur atoms, X′ represents O, S, or NR″, whereby R″ represents a hydrogen atom or a straight or branched C1-C6 alkyl group, C3-C6 cycloalkyl group, or C4-C8 cycloalkylalkyl group, m is 0 to 3, and n is 1 to 3.

    摘要翻译： 含有聚合物主链中具有重复单元的聚合性聚酸聚合物的牙科水泥组合物，其由下式（I）1（II）和/或（III）表示：其中X表示O，S或NR'，由此 R'表示氢原子或直链或支链C1-C6烷基，C3-C6环烷基或C4-C8环烷基烷基，Y为下式（Ⅳ）的基团，其中L1，L2，L3和 L4彼此独立地表示单键，直链或支链C1-C6亚烷基，直链或支链C1-C6亚烯基或包含1至8个选自以下的1至8个原子的直链或支链C 1 -C 20亚烷基 氧原子和硫原子，X'表示O，S或NR“，其中R”表示氢原子或直链或支链C 1 -C 6烷基，C 3 -C 6环烷基或C 4 -C 8环烷基烷基，m为0 至3，n为1至3。

    DENTAL COMPOSITION
    10.
    发明申请
    DENTAL COMPOSITION 有权
    牙科成分

    公开(公告)号：US20120214900A1

    公开(公告)日：2012-08-23

    申请号：US13504949

    申请日：2010-11-02

    申请人： Joachim E. Klee ,  Oliver Elsner ,  Sven Pohle ,  Helmut Ritter ,  Dominika Bernert

    发明人： Joachim E. Klee ,  Oliver Elsner ,  Sven Pohle ,  Helmut Ritter ,  Dominika Bernert

    IPC分类号： A61K6/083 ,  C08F267/04 ,  C08F8/34 ,  C08F265/04 ,  C08F20/12 ,  C08F22/06

    CPC分类号： A61K6/0835 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0038 ,  C08L33/00

    摘要： An aqueous dental glass ionomer composition comprising (a) a reactive particulate glass, (b) a linear or branched polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the linear or branched polymer comprising acidic groups has a polymer backbone and optionally pendant groups, (c) optionally dispersed nanoparticles comprising grafted linear or branched polymer chains comprising acidic groups, and having a polymer backbone characterized in that a polymer backbone of the linear or branched polymer of component (b) and/or, if present, the grafted Sinear or branched polymer chains of component (c) are obtainable a process comprising (i) cyclopolymerizing or cyclocopolymerizing one or more compounds of the following formula (I).

    摘要翻译： 一种水性牙科玻璃离聚物组合物，其包含（a）反应性颗粒玻璃，（b）包含酸性基团的直链或支链聚合物，其在水泥反应中与颗粒状玻璃反应，由此包含酸性基团的直链或支链聚合物具有 聚合物主链和任选的侧基，（c）任选分散的纳米颗粒，其包含含有酸性基团的接枝的直链或支链聚合物链，并且具有聚合物主链，其特征在于组分（b）和/ 如果存在，组分（c）的接枝的正弦或支链聚合物链可以通过以下方法获得：（i）使一种或多种下式（I）的化合物环聚或环化聚合。