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公开(公告)号：US09676850B2
公开(公告)日：2017-06-13
申请号：US14380665
申请日：2013-02-22
Applicant: STEM CENTRX, INC.
Inventor： Laura Saunders , Scott J. Dylla , Orit Foord , Robert A. Stull , Michael Torgov , Hui Shao , David Liu
CPC classification number: C07K16/28 , A61K47/6849 , A61K2039/505 , C07K2317/24 , C07K2317/33 , C07K2317/565 , C07K2317/76 , C07K2317/77
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
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公开(公告)号：US08986972B2
公开(公告)日：2015-03-24
申请号：US14466939
申请日：2014-08-22
Applicant: Stem CentRx, Inc.
Inventor： Robert A. Stull , Laura Saunders , Scott J. Dylla , Orit Foord , David Liu , Michael Torgov , Hui Shao
CPC classification number: A61K47/6803 , A61K31/551 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/48384 , A61K47/48407 , A61K47/48469 , A61K47/48538 , A61K47/48561 , A61K47/48592 , A61K47/48638 , A61K47/48715 , A61K47/48723 , A61K47/6809 , A61K47/6811 , A61K47/6813 , A61K47/6825 , A61K47/6829 , A61K47/6843 , A61K47/6849 , A61K47/6851 , A61K47/6855 , A61K47/6857 , A61K47/6859 , A61K47/6861 , A61K47/6867 , A61K47/6869 , A61K47/6889 , A61K47/6891 , A61K51/1096 , A61K2039/505 , A61K2039/572 , C07D487/04 , C07D487/16 , C07K16/18 , C07K16/28 , C07K16/2809 , C07K16/30 , C07K16/3023 , C07K16/3069 , C07K2317/20 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/70 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , G01N33/57423 , G01N33/57492 , G01N2333/70596
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Abstract translation: 提供了新型调节剂，包括抗体及其衍生物，以及使用这些调节剂治疗增殖性疾病的方法。
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公开(公告)号：US20150030636A1
公开(公告)日：2015-01-29
申请号：US14454107
申请日：2014-08-07
Applicant: STEM CENTRX, INC.
Inventor： SCOTT J. DYLLA , MARIANNE SANTAGUIDA , WADE C. ANDERSON , BOB Y. LIU , SAMUEL A. WILLIAMS
IPC: G01N33/574 , A61K39/00
CPC classification number: G01N33/57492 , A61K39/0011 , C12N5/0693
Abstract: Markers useful for the identification, characterization and, optionally, the enrichment or isolation of tumorigenic cells or cell subpopulations are disclosed.
Abstract translation: 公开了用于鉴定，表征和任选地富集或分离致瘤细胞或细胞亚群的标记物。
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公开(公告)号：US09381205B2
公开(公告)日：2016-07-05
申请号：US14525442
申请日：2014-10-28
Applicant: Pfizer, Inc. , Stem CentRx, Inc.
Inventor： Marc Isaac Damelin , Kiran Manohar Khandke , Puja Sapra , Alexander John Bankovich , Scott J. Dylla
IPC: A61K39/395 , A61K31/704 , A61K47/48 , C07K16/30
CPC classification number: A61K47/6849 , A61K31/704 , A61K47/6807 , A61K47/6851 , C07K16/30 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/77
Abstract: The present invention provides for anti-EFNA4 antibody-drug conjugates and methods for preparing and using the same.
Abstract translation: 本发明提供抗EFNA4抗体 - 药物偶联物及其制备和使用方法。
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公开(公告)号：US09089617B2
公开(公告)日：2015-07-28
申请号：US14466951
申请日：2014-08-22
Applicant: STEM CENTRX, INC.
Inventor： Robert A. Stull , Laura Saunders , Scott J. Dylla , Orit Foord , David Liu , Michael Torgov , Hui Shao
IPC: A61K39/395 , C07K16/18 , C12P21/08 , A61K47/48 , C07K16/28 , C07K16/30 , A61K31/5517 , G01N33/574 , A61K39/00
CPC classification number: A61K47/6803 , A61K31/551 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/48384 , A61K47/48407 , A61K47/48469 , A61K47/48538 , A61K47/48561 , A61K47/48592 , A61K47/48638 , A61K47/48715 , A61K47/48723 , A61K47/6809 , A61K47/6811 , A61K47/6813 , A61K47/6825 , A61K47/6829 , A61K47/6843 , A61K47/6849 , A61K47/6851 , A61K47/6855 , A61K47/6857 , A61K47/6859 , A61K47/6861 , A61K47/6867 , A61K47/6869 , A61K47/6889 , A61K47/6891 , A61K51/1096 , A61K2039/505 , A61K2039/572 , C07D487/04 , C07D487/16 , C07K16/18 , C07K16/28 , C07K16/2809 , C07K16/30 , C07K16/3023 , C07K16/3069 , C07K2317/20 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/70 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , G01N33/57423 , G01N33/57492 , G01N2333/70596
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Abstract translation: 提供了新型调节剂，包括抗体及其衍生物，以及使用这些调节剂治疗增殖性疾病的方法。
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Patent Agency Ranking
公开(公告)号：US09089615B2
公开(公告)日：2015-07-28
申请号：US14466842
申请日：2014-08-22
Applicant: STEM CENTRX, INC.
Inventor： Robert A. Stull , Laura Saunders , Scott J. Dylla , Orit Foord , David Liu , Michael Torgov , Hui Shao
IPC: A61K39/395 , C07K16/18 , C12P21/08 , A61K47/48 , C07K16/28 , C07K16/30 , A61K31/5517 , G01N33/574 , A61K39/00
CPC classification number: A61K47/6803 , A61K31/551 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/48384 , A61K47/48407 , A61K47/48469 , A61K47/48538 , A61K47/48561 , A61K47/48592 , A61K47/48638 , A61K47/48715 , A61K47/48723 , A61K47/6809 , A61K47/6811 , A61K47/6813 , A61K47/6825 , A61K47/6829 , A61K47/6843 , A61K47/6849 , A61K47/6851 , A61K47/6855 , A61K47/6857 , A61K47/6859 , A61K47/6861 , A61K47/6867 , A61K47/6869 , A61K47/6889 , A61K47/6891 , A61K51/1096 , A61K2039/505 , A61K2039/572 , C07D487/04 , C07D487/16 , C07K16/18 , C07K16/28 , C07K16/2809 , C07K16/30 , C07K16/3023 , C07K16/3069 , C07K2317/20 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/70 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , G01N33/57423 , G01N33/57492 , G01N2333/70596
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Abstract translation: 提供了新型调节剂，包括抗体及其衍生物，以及使用这些调节剂治疗增殖性疾病的方法。
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公开(公告)号：US20150337048A1
公开(公告)日：2015-11-26
申请号：US14377343
申请日：2013-02-08
Applicant: STEM CENTRX, INC.
Inventor： Robert A. STULL , Monette AUJAY , Orit FOORD , Alex BANKOVICH , Johannes HAMPL , Scott J. DYLLA , David LIU
CPC classification number: C07K16/2896 , A61K47/6849 , A61K47/6879 , A61K47/6897 , A61K2039/505 , C07K16/2803 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Abstract translation: 提供了新型调节剂，包括抗体及其衍生物，以及使用这些调节剂治疗增殖性疾病的方法。
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8.发明授权公开(公告)号：US09090683B2
公开(公告)日：2015-07-28
申请号：US14466948
申请日：2014-08-22
Applicant: STEM CENTRX, INC.
Inventor： Robert A. Stull , Laura Saunders , Scott J. Dylla , Orit Foord , David Liu , Michael Torgov , Hui Shao
IPC: G01N33/53 , G01N33/563 , G01N33/577 , A61K39/395 , C07K16/18 , C07K16/28 , C07K16/30 , A61K47/48 , A61K31/5517 , G01N33/574 , A61K39/00
CPC classification number: A61K47/6803 , A61K31/551 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/48384 , A61K47/48407 , A61K47/48469 , A61K47/48538 , A61K47/48561 , A61K47/48592 , A61K47/48638 , A61K47/48715 , A61K47/48723 , A61K47/6809 , A61K47/6811 , A61K47/6813 , A61K47/6825 , A61K47/6829 , A61K47/6843 , A61K47/6849 , A61K47/6851 , A61K47/6855 , A61K47/6857 , A61K47/6859 , A61K47/6861 , A61K47/6867 , A61K47/6869 , A61K47/6889 , A61K47/6891 , A61K51/1096 , A61K2039/505 , A61K2039/572 , C07D487/04 , C07D487/16 , C07K16/18 , C07K16/28 , C07K16/2809 , C07K16/30 , C07K16/3023 , C07K16/3069 , C07K2317/20 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/70 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , G01N33/57423 , G01N33/57492 , G01N2333/70596
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Abstract translation: 提供了新型调节剂，包括抗体及其衍生物，以及使用这些调节剂治疗增殖性疾病的方法。
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公开(公告)号：US09089616B2
公开(公告)日：2015-07-28
申请号：US14466945
申请日：2014-08-22
Applicant: STEM CENTRX, INC.
Inventor： Robert A Stull , Laura Saunders , Scott J. Dylla , Orit Foord , David Liu , Michael Torgov , Hui Shao
IPC: A61K39/395 , C07K16/00 , C07K16/28 , A61K47/48 , C07K16/30 , A61K31/5517 , G01N33/574 , C07K16/18 , A61K39/00
CPC classification number: A61K47/6803 , A61K31/551 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/48384 , A61K47/48407 , A61K47/48469 , A61K47/48538 , A61K47/48561 , A61K47/48592 , A61K47/48638 , A61K47/48715 , A61K47/48723 , A61K47/6809 , A61K47/6811 , A61K47/6813 , A61K47/6825 , A61K47/6829 , A61K47/6843 , A61K47/6849 , A61K47/6851 , A61K47/6855 , A61K47/6857 , A61K47/6859 , A61K47/6861 , A61K47/6867 , A61K47/6869 , A61K47/6889 , A61K47/6891 , A61K51/1096 , A61K2039/505 , A61K2039/572 , C07D487/04 , C07D487/16 , C07K16/18 , C07K16/28 , C07K16/2809 , C07K16/30 , C07K16/3023 , C07K16/3069 , C07K2317/20 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/70 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , G01N33/57423 , G01N33/57492 , G01N2333/70596
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Abstract translation: 提供了新型调节剂，包括抗体及其衍生物，以及使用这些调节剂治疗增殖性疾病的方法。
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公开(公告)号：US20140370037A1
公开(公告)日：2014-12-18
申请号：US14466941
申请日：2014-08-22
Applicant: STEM CENTRX, INC.
Inventor： ROBERT A. STULL , LAURA SAUNDERS , SCOTT J. DYLLA , ORIT FOORD , DAVID LIU , MICHAEL TORGOV , HUI SHAO
CPC classification number: A61K47/6803 , A61K31/551 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/48384 , A61K47/48407 , A61K47/48469 , A61K47/48538 , A61K47/48561 , A61K47/48592 , A61K47/48638 , A61K47/48715 , A61K47/48723 , A61K47/6809 , A61K47/6811 , A61K47/6813 , A61K47/6825 , A61K47/6829 , A61K47/6843 , A61K47/6849 , A61K47/6851 , A61K47/6855 , A61K47/6857 , A61K47/6859 , A61K47/6861 , A61K47/6867 , A61K47/6869 , A61K47/6889 , A61K47/6891 , A61K51/1096 , A61K2039/505 , A61K2039/572 , C07D487/04 , C07D487/16 , C07K16/18 , C07K16/28 , C07K16/2809 , C07K16/30 , C07K16/3023 , C07K16/3069 , C07K2317/20 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/70 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , G01N33/57423 , G01N33/57492 , G01N2333/70596
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
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