Stable liquid compositions for treating stomatitis comprising epidermal growth factor
    1.
    发明授权
    Stable liquid compositions for treating stomatitis comprising epidermal growth factor 有权
    用于治疗包含表皮生长因子的口腔炎的稳定液体组合物

    公开(公告)号:US09155697B2

    公开(公告)日:2015-10-13

    申请号:US12444961

    申请日:2007-10-09

    CPC classification number: A61K9/006 A61K38/1808 A61K47/10 C07K14/485

    Abstract: Provided is a liquid composition for treating stomatitis, the liquid composition including: an epidermal growth factor; an adhesive polymer; and at least one stabilizer selected from the group consisting of ethylenediaminetetraacetic acid (EDTA) and salts thereof, histidine, lysine and inorganic acid salts thereof, arginin and inorganic acid salts thereof, and dextran. The liquid composition includes a stabilizer selected from EDTA (or salts thereof) and a certain amino acid (or inorganic acid salts thereof) and thus, physicochemical and biological stability of the epidermal growth factor can be substantially increased. Thus, the liquid composition can be stored and distributed for a long period of time. The stabilized composition includes an adhesive polymer, and thus, when ejected in a spray form in the mouth of a user, the liquid composition can be quickly attached to an inflammation site and exhibits effectiveness for a long period of time.

    Abstract translation: 本发明提供一种用于治疗口腔炎的液体组合物,该液体组合物包括:表皮生长因子; 粘合剂聚合物; 和选自乙二胺四乙酸(EDTA)及其盐,组氨酸,赖氨酸及其无机酸盐,精氨酸及其无机酸盐和右旋糖酐的至少一种稳定剂。 液体组合物包括选自EDTA(或其盐)和某些氨基酸(或其无机酸盐)的稳定剂,因此可以显着增加表皮生长因子的物理化学和生物学稳定性。 因此,液体组合物可以长期储存和分配。 稳定化的组合物包括粘合剂聚合物,因此当以使用者口中喷雾形式喷射时,液体组合物可以快速地附着于炎症部位并且长时间显示出有效性。

    Methods of generating three-dimensional process window qualification
    3.
    发明授权
    Methods of generating three-dimensional process window qualification 有权
    生成三维过程窗口资格的方法

    公开(公告)号:US08703405B2

    公开(公告)日:2014-04-22

    申请号:US13462250

    申请日:2012-05-02

    CPC classification number: G03F7/70616 G03F7/705

    Abstract: In a method of generating a three-dimensional process window qualification, a photoresist layer is coated on a substrate including an underlying structure. A plurality of circular-shaped regions of the substrate are distinguished into 1 to n regions to partition the substrate into a center portion and an edge portion, n being a natural number greater than 2. 1 to n exposing ranges are set, including a common exposing condition for the 1 to n regions. A photoresist pattern is fox led by exposing each shot portion in the 1 to n regions using a split exposing condition in the 1 to n exposing ranges. The photoresist pattern is detected, and a normal photoresist pattern with respect to each of the 1 to n regions is selected to generate the three-dimensional process window qualification.

    Abstract translation: 在产生三维工艺窗口鉴定的方法中,光致抗蚀剂层被涂覆在包括下面的结构的衬底上。 衬底的多个圆形区域被区分为1到n个区域,以将衬底分成中心部分和边缘部分,n是大于2的自然数,1至n个曝光范围被设置,包括公共 暴露1〜n个区域的状况。 光致抗蚀剂图案是通过在1至n个曝光范围内使用分割曝光条件曝光1至n个区域中的每个拍摄部分来引导的狐狸。 检测光致抗蚀剂图案,并且选择相对于1至n个区域中的每一个的常规光致抗蚀剂图案以产生三维工艺窗口鉴定。

    Nanoliposome using esterified lecithin and method for preparing the same, and composition for preventing or treating skin diseases comprising the same
    4.
    发明授权
    Nanoliposome using esterified lecithin and method for preparing the same, and composition for preventing or treating skin diseases comprising the same 有权
    使用酯化卵磷脂的纳米脂质体及其制备方法,以及用于预防或治疗包含其的皮肤病的组合物

    公开(公告)号:US08685440B2

    公开(公告)日:2014-04-01

    申请号:US12375739

    申请日:2007-08-01

    Abstract: The present invention relates to a nanoliposome comprising a liposome membrane containing esterified lecithin, and one or more physiologically active ingredients included in inner space of the liposome membrane; a method for preparing the same; and a composition for preventing or treating skin diseases, comprising the same. The nanoliposome according to the present invention has long-term stability and uniformity, and so can be used to prepare a composition for skin having excellent moisturizing and penetrating properties, such as cosmetics, medicament for treating skin diseases, or the like. In particular, the present composition for preventing or treating skin diseases comprises epidermal growth factor included in the nanoliposome, thereby showing an excellent effect of stimulating skin-penetration and good pharmaceutical stability. Also, the esterified lecithin used in preparing liposome can provide effects of softening skin and stimulating skin-penetration, thereby enhancing the penetration of epidermal growth factor and natural extract into skin, as well as additional moisturizing effect which is advantageous in treating skin diseases. Further, since the present composition comprises nanoliposome prepared by containing esterified lecithin in liposome membrane, the conventional problems of heating and dispersing active ingredients at high temperature (70° C. or more), low stability and uniformity, or the like can be solved.

    Abstract translation: 本发明涉及包含含有酯化卵磷脂的脂质体膜和包含在脂质体膜的内部空间中的一种或多种生理活性成分的纳米脂质体, 其制备方法; 以及用于预防或治疗皮肤病的组合物。 根据本发明的纳米脂质体具有长期的稳定性和均匀性,因此可以用于制备具有优异的保湿和渗透性的皮肤组合物,例如化妆品,用于治疗皮肤病的药物等。 特别地,本发明的皮肤病预防或治疗组合物包括纳米脂质体中所含的表皮生长因子,因此显示刺激皮肤渗透和良好药物稳定性的优异效果。 此外,用于制备脂质体的酯化卵磷脂可以提供软化皮肤和刺激皮肤渗透的作用,从而增强表皮生长因子和天然提取物对皮肤的渗透性,以及有利于治疗皮肤疾病的额外的保湿效果。 此外,由于本发明的组合物包含通过在脂质体膜中含有酯化的卵磷脂而制备的纳米脂质体,因此可以解决在高温(70℃以上)下加热分散有效成分的常规问题,稳定性和均匀性低等。

    INFLATABLE FABRICS AND AN AIR-BAG
    5.
    发明申请
    INFLATABLE FABRICS AND AN AIR-BAG 审中-公开
    充气织物和空气袋

    公开(公告)号:US20100253047A1

    公开(公告)日:2010-10-07

    申请号:US12740088

    申请日:2008-12-26

    Abstract: Disclosed is a inflatable double-layered fabric. The fabric includes an inflating part having gas inflatability, a non-inflating part supporting the inflating part, and a co-woven part constituting a boundary between the inflating part and the non-inflating part, wherein the inflating part is composed of two separated fabric layers, and the weave of the co-woven part is set up at a nk+1 pixel from the width or length end of the double-layered fabric (where, k is 2 or 3, and n is 0 or a positive number) when dividing the double-layered fabric into a plurality of pixels, an airbag including the same, and a method of preparing the airbag.

    Abstract translation: 公开了一种可膨胀的双层织物。 织物包括具有气体充气性的充气部,支撑充气部的非充气部,以及构成充气部与非充气部之间的边界的共纺织部,其中,充气部由两个分离的织物 层叠,并且从双层织物的宽度或长度端(其中,k为2或3,n为0或正数),将织造部分的织物设置在nk + 1像素处, 当将双层织物分成多个像素时,包括该气囊的气囊和制造气囊的方法。

    Integrated control system for vehicles
    7.
    发明申请
    Integrated control system for vehicles 审中-公开
    车辆综合控制系统

    公开(公告)号:US20090093933A1

    公开(公告)日:2009-04-09

    申请号:US12287444

    申请日:2008-10-08

    CPC classification number: B60W50/00 B60W10/00 B60W10/184 B60W10/20 B60W10/22

    Abstract: The present invention relates to an integrated safety control system for vehicles. In particular, the present invention includes a sensor unit, an actuating unit, an actuating control unit, and an integrated control unit. The sensor unit includes a plurality of sensors for outputting sensed signals required for chassis control and Advanced Safety Vehicle (ASV) control of the vehicle. The actuating unit includes a plurality of actuating subunits for performing the chassis control and the ASV control. The actuating control unit includes a plurality of actuating control subunits provided for the respective actuating subunits, and configured to operate the respective actuating subunits. The integrated control unit compares and analyzes the sensed signals and selectively controls the respective actuating subunits so as to perform chassis control and ASV control in an integrated control manner.

    Abstract translation: 本发明涉及一种用于车辆的综合安全控制系统。 特别地,本发明包括传感器单元,致动单元,致动控制单元和集成控制单元。 传感器单元包括用于输出车辆控制和车辆的高级安全车辆(ASV)控制所需的感测信号的多个传感器。 致动单元包括用于执行底盘控制和ASV控制的多个致动子单元。 致动控制单元包括为相应的致动子单元提供的多个致动控制子单元,并被配置为操作相应的致动子单元。 集成控制单元比较和分析所感测的信号,并且选择性地控制相应的致动子单元,以便以集成的控制方式执行底盘控制和ASV控制。

    Portable storage apparatus and method for freely changing data bus width
    8.
    发明授权
    Portable storage apparatus and method for freely changing data bus width 有权
    便携式存储装置和方法可自由更改数据总线宽度

    公开(公告)号:US07234031B2

    公开(公告)日:2007-06-19

    申请号:US10866602

    申请日:2004-06-12

    CPC classification number: G06F3/0659 G06F3/0605 G06F3/0679

    Abstract: A portable storage apparatus capable of freely changing a data bus width and a method of setting the data bus width of the apparatus are provided, where the portable storage apparatus has at least one command line and a plurality of data lines, and includes a non-volatile memory, a command packet decoder, and a control unit, such that the non-volatile memory stores data, the command packet decoder receives command packets through a command line and outputs command information by decoding the received command packets, the command packet decoder receives a data transmit command packet or a data request command packet and outputs a write command or a read command, address information, and data bus width information, the control unit performs a control operation in response to the command information and selects all or some of the plurality of data lines in response to the data bus width information and receives or transmits the data through the selected data line, and controls data writing or reading of the non-volatile memory in response to the write command or the read command and the address information, thereby not requiring the data bus width to be set in advance and enabling free adjustment of the data bus width, if necessary.

    Abstract translation: 提供一种能够自由地改变数据总线宽度的便携式存储装置和设置数据总线宽度的方法,其中便携式存储装置具有至少一条命令行和多条数据线, 易失性存储器,命令包解码器和控制单元,使得非易失性存储器存储数据,命令包解码器通过命令行接收命令包,并通过解码接收到的命令包来输出命令信息,命令包解码器接收 数据发送命令包或数据请求命令包,并且输出写入命令或读取命令,地址信息和数据总线宽度信息,所述控制单元响应于命令信息执行控制操作,并选择所有或某些 响应于数据总线宽度信息的多条数据线,并通过选择的数据线接收或发送数据,并控制数据写入 g或响应于写入命令或读取命令和地址信息读取非易失性存储器,从而不需要预先设置数据总线宽度,并且如果需要可以自由调整数据总线宽度。

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